Efficacy News and Research

RSS

What is currently known about immune responses to COVID-19 vaccines and cellular immune responses against SARS-CoV-2?

Researchers summarized existing data on the immunogenicity of COVID-19 vaccines and the humoral and cellular immune responses against SARS-CoV-2.

2 Sep 2022

What is the risk of BA.5 infection among persons with documented infection with past variants?

A recent correspondence discussed a study in which researchers assessed the infection risk for the SARS-CoV-2 Omicron BA.5 subvariant in vaccinated people exposed to previous SARS-CoV-2 variants.

2 Sep 2022

A rapid and efficient method of identifying neutralizing nanobodies directed against SARS-CoV-2

A recent PLoS ONE study detected neutralizing nanobodies against SARS-CoV-2 from nanobody phage display libraries and via in vitro and ex vivo high-throughput screenings.

2 Sep 2022

Intranasally delivered neutralizing antibody protects against SARS-CoV-2 Omicron and Delta variants

The current study focused on the ability of this nmAb to neutralize Delta, Omicron, and other VOCs, as well as its efficacy when given by the intranasal route in an animal model.

1 Sep 2022

Less is more: early short-course rapamycin effective in sustained anti-aging effects

A new study shows that a brief treatment period could have the same anti-aging efficacy and duration of effect but without the potentially serious adverse effects of chronic administration.

1 Sep 2022

Molecular fate-mapping of antibodies shows effects of antigenic imprinting

In a new study, researchers developed a molecular fate-mapping method for differential detection of antibodies derived from specific B cell clones.

1 Sep 2022

Can SARS-CoV-2 transmission occur from an infected dead body?

In new research, researchers determined whether severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) could be transmitted from a dead body.

1 Sep 2022

Scientists develop a novel solution to evaluate airborne transmission of SARS-CoV-2

Scientists from Germany have developed a novel mathematical model to study the airborne transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

31 Aug 2022

What lessons can we learn from the COVID-19 pandemic for HIV?

A new study discussed how experiences from the coronavirus disease 2019 (COVID-19) pandemic could be leveraged for human immunodeficiency virus (HIV).

31 Aug 2022

How effective was the Shanghai lockdown policy compared with that of other countries?

A recent study aimed to fill this gap in research by evaluating the impact of strict lockdown measures on SARS-CoV-2 Omicron transmission in Shanghai between March and April 2022.

31 Aug 2022

Study explores differences in the efficiency of COVID-19 vaccine boosters

In a new study, researchers predicted the efficacy of coronavirus disease 2019 (COVID-19) vaccine boosters.

30 Aug 2022

Research reveals administration of ineffective COVID-19 treatments after FDA deauthorization

Monoclonal antibodies are laboratory-designed treatments tailor-made to fight specific infections. In early 2021, the U.S. Food & Drug Administration issued emergency use authorization for two monoclonal antibodies (bamlanivimab/etesevimab and casirivimab/imdevimab) for the treatment of mild to moderate COVID-19 in high-risk, non-hospitalized patients.

30 Aug 2022

3 shots in 1: How microparticles could be used to deliver self-boosting vaccines

In this interview, we speak to Morteza Sarmadi from MIT about his labs latest research that developed microparticles able to deliver self-boosting vaccines.

30 Aug 2022

Researchers report the exceptional binding and neutralizing potency of an ACE2 decoy against SARS-CoV-2 variants

Researchers explored the activity of an ACE2 decoy against SARS-CoV-2 Omicron variant.

30 Aug 2022

Study reveals a novel therapeutic strategy to overcome tumor-induced immunosuppression

A study led by LSU Health New Orleans cancer researchers describes a novel therapeutic strategy to overcome tumor-induced immunosuppression.

29 Aug 2022

Viruses modify host cellular machinery to produce high amounts of viral progeny

The study, published in Nature Communications, shows a new mechanism whereby viruses modify cellular machinery so that it can better read the instructions in the genome of the invading virus.

29 Aug 2022

EPFL scientists uncover key mechanisms underlying the formation of protein tangles in the brain

Neurodegenerative disorders such as Alzheimer's and Parkinson's disease are associated with atypical proteins that form tangles in the brain, killing neurons.

29 Aug 2022

The clinical and virological outcomes associated with molnupiravir or nirmatrelvir–ritonavir use in hospitalized patients with mild-to-moderate COVID-19

Researchers investigated whether early treatment with oral antivirals prevented all-cause mortality in hospitalized patients infected with SARS-CoV-2 new variant of concern Omicron BA.2 subvariant.

29 Aug 2022

The effectiveness of nirmatrelvir in preventing severe COVID-19 outcomes during the Omicron surge

Researchers assessed the clinical efficacy of nirmatrelvir in preventing severe COVID-19 in Israel during the Omicron wave.

29 Aug 2022

New risk assessment tool predicts mortality for atrial fibrillation patients after completion of TAVR

A large-scale international study led by Mount Sinai has yielded the first risk score that can help predict mortality for patients with atrial fibrillation (AFib) who have undergone a successful transcatheter aortic valve replacement (TAVR) and discharged home.

29 Aug 2022

Efficacy News and Research

What is currently known about immune responses to COVID-19 vaccines and cellular immune responses against SARS-CoV-2?

What is the risk of BA.5 infection among persons with documented infection with past variants?

A rapid and efficient method of identifying neutralizing nanobodies directed against SARS-CoV-2

Intranasally delivered neutralizing antibody protects against SARS-CoV-2 Omicron and Delta variants

Less is more: early short-course rapamycin effective in sustained anti-aging effects

Molecular fate-mapping of antibodies shows effects of antigenic imprinting

Can SARS-CoV-2 transmission occur from an infected dead body?

Scientists develop a novel solution to evaluate airborne transmission of SARS-CoV-2

What lessons can we learn from the COVID-19 pandemic for HIV?

How effective was the Shanghai lockdown policy compared with that of other countries?

Study explores differences in the efficiency of COVID-19 vaccine boosters

Research reveals administration of ineffective COVID-19 treatments after FDA deauthorization

3 shots in 1: How microparticles could be used to deliver self-boosting vaccines

Researchers report the exceptional binding and neutralizing potency of an ACE2 decoy against SARS-CoV-2 variants

Study reveals a novel therapeutic strategy to overcome tumor-induced immunosuppression

Viruses modify host cellular machinery to produce high amounts of viral progeny

EPFL scientists uncover key mechanisms underlying the formation of protein tangles in the brain

The clinical and virological outcomes associated with molnupiravir or nirmatrelvir–ritonavir use in hospitalized patients with mild-to-moderate COVID-19

The effectiveness of nirmatrelvir in preventing severe COVID-19 outcomes during the Omicron surge

New risk assessment tool predicts mortality for atrial fibrillation patients after completion of TAVR

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Latest News