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Study links nanoplastics to Parkinson's disease and dementia

Nanoplastics interact with a particular protein that is naturally found in the brain, creating changes linked to Parkinson's disease and some types of dementia.

17 Nov 2023

RIT scientist earns NIH award to support research on building the next generation of drugs

Rochester Institute of Technology's Emiliano Brini, assistant professor in the School of Chemistry and Materials Science, has received an award from the National Institutes of Health (NIH) to support his research on building the next generation of drugs.

17 Nov 2023

Researchers develop new method to detect protein aggregates in neurodegenerative diseases

Proteins misfolding and clumping together, a process known as aggregation, is a key feature seen in several neurological conditions, including Alzheimer's and Parkinson's diseases.

17 Nov 2023

Novel tool can help with analysis of single cell data

CITE-seq (cellular indexing of transcriptomes and epitopes) is an RNA sequencing-based method that simultaneously quantifies cell surface protein and transcriptomic data within a single cell readout.

17 Nov 2023

New insights into sporadic early-onset Alzheimer's disease

Alzheimer's disease (AD), the most prevalent neurodegenerative disease globally, poses a significant threat to human health.

17 Nov 2023

AGA guideline recommends biomarkers for Crohn's disease management

The American Gastroenterological Association (AGA) released a new evidence-based guideline recommending the use of blood and stool-based biomarkers to help manage Crohn's disease, a type of inflammatory bowel disease (IBD).

17 Nov 2023

Ketogenic diets and diabetes: A promising match or a questionable pair?

A recent research article in "Diabetes Therapy" examines the effectiveness of ketogenic diets in managing Type 1, Type 2, and gestational diabetes. Despite potential benefits like weight loss and improved glycemic control, the study highlights unresolved issues and the need for more extensive research before incorporating ketogenic diets into clinical guidelines for diabetes management.

16 Nov 2023

Coffee and COVID: Study finds coffee inhibits SARS-CoV-2, offers new dietary defense strategy

Study discovers that coffee, especially its bioactive compounds like chlorogenic acids, can inhibit SARS-CoV-2 entry and reduce ACE2 and TMPRSS2 levels, indicating that coffee intake might be a potential dietary strategy for COVID-19 prevention.

16 Nov 2023

Gene splicing determines CD20 levels and response to monoclonal antibody therapy

Immunotherapies that target the CD20 antigen have revolutionized how patients with a variety of blood cancers and hematologic disorders have been treated.

16 Nov 2023

Molecular trap offers hope for ALS treatment

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that affects neurons in the brain and spinal cord causing loss of muscle control.

16 Nov 2023

Emerging tick-borne viral threats in eastern europe and the black sea basin

Tick samples from countries in Eastern Europe and the Black Sea region.

16 Nov 2023

Rare APOE3-R136S mutation offers protection against Alzheimer's disease pathologies in new study

The R136S genetic mutation protected against apolipoprotein E4 (APOE4)-induced late-onset Alzheimer’s disease (LOAD).

16 Nov 2023

One in five patients on Nirmatrelvir–Ritonavir experience virologic rebound, new observational study reveals

The frequency of viral rebound (VR) among acute coronavirus disease 2019 patients.

16 Nov 2023

Curcumin boosts brain delivery of HIV drug, curbing inflammation and oxidative stress

Study shows curcumin enhances antiretroviral delivery and reduces inflammation and oxidative stress in HIV, offering potential improvements in treating HIV-associated neurocognitive disorders.

16 Nov 2023

New study highlights urgent need for specific biomarkers in vascular cognitive impairment and dementia diagnosis

A review in Nature Reviews Neurology discusses the pathophysiological processes in vascular cognitive impairment and dementia (VCID), emphasizing the need for specific biomarkers to differentiate VCID from Alzheimer's disease and to improve diagnosis and treatment strategies, moving beyond reliance on neuroimaging and patient histories.

15 Nov 2023

Fecal microbiota transplantation boosts survival in metastatic colorectal cancer treatment

A recent study in eClinicalMedicine found that fecal microbiota transplantation, combined with fruquintinib and tislelizumab, significantly improved survival rates in patients with microsatellite stable metastatic colorectal cancer, showing manageable safety and notable increases in progression-free and overall survival.

15 Nov 2023

PanKind grants critical funding to develop the first early detection blood test for pancreatic cancer

Research that could lead to the first early detection blood test for pancreatic cancer has received critical funding from PanKind, The Australian Pancreatic Cancer Foundation.

15 Nov 2023

Shrinkage in the brain's hippocampus area associated with cognitive decline

With the rise of new drugs that can target the amyloid-beta plaques in the brain that are an early sign of Alzheimer's disease, new ways are needed to determine whether memory loss and thinking problems are due to Alzheimer's disease or another neurodegenerative disorder.

15 Nov 2023

Experts question Pfizer's failure to inform pregnant women of safety signal in GSK RSV vaccine trial

A debate has broken out over whether Pfizer should have told pregnant women taking part in its maternal respiratory syncytial virus (RSV) vaccine trial that a trial of a similar GSK vaccine was stopped over a safety signal around preterm birth, an investigation by The BMJ can reveal.

15 Nov 2023

Senolytics show promise in combating brain aging and COVID-19 neuropathology

Study reveals that senolytics can reduce aging in human brain organoids and mitigate COVID-19 neuropathology, suggesting their potential as a therapeutic strategy against brain aging and coronavirus-related neurological complications.

15 Nov 2023

Protein C News and Research

Study links nanoplastics to Parkinson's disease and dementia

RIT scientist earns NIH award to support research on building the next generation of drugs

Researchers develop new method to detect protein aggregates in neurodegenerative diseases

Novel tool can help with analysis of single cell data

New insights into sporadic early-onset Alzheimer's disease

AGA guideline recommends biomarkers for Crohn's disease management

Ketogenic diets and diabetes: A promising match or a questionable pair?

Coffee and COVID: Study finds coffee inhibits SARS-CoV-2, offers new dietary defense strategy

Gene splicing determines CD20 levels and response to monoclonal antibody therapy

Molecular trap offers hope for ALS treatment

Emerging tick-borne viral threats in eastern europe and the black sea basin

Rare APOE3-R136S mutation offers protection against Alzheimer's disease pathologies in new study

One in five patients on Nirmatrelvir–Ritonavir experience virologic rebound, new observational study reveals

Curcumin boosts brain delivery of HIV drug, curbing inflammation and oxidative stress

New study highlights urgent need for specific biomarkers in vascular cognitive impairment and dementia diagnosis

Fecal microbiota transplantation boosts survival in metastatic colorectal cancer treatment

PanKind grants critical funding to develop the first early detection blood test for pancreatic cancer

Shrinkage in the brain's hippocampus area associated with cognitive decline

Experts question Pfizer's failure to inform pregnant women of safety signal in GSK RSV vaccine trial

Senolytics show promise in combating brain aging and COVID-19 neuropathology

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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