Glucose News and Research

RSS

MiR-34a plays a key role in obesity

Scientists have identified a key molecular player in a chain of events in the body that can lead to fatty liver disease, Type II diabetes and other metabolic abnormalities associated with obesity. By blocking this molecule, the researchers were able to reverse some of the pathology it caused in obese mice.

21 Sep 2012

Tight glycemic control does not reduce infection rate after pediatric cardiac surgery

Implementing tight glycemic control after surgery with cardiopulmonary bypass does not reduce the rate of healthcare-associated infections among pediatric patients, compared with standard care in the intensive care unit, show US study results.

20 Sep 2012

Obese adults with excess visceral fat, biomarkers of insulin resistance more likely to develop diabetes

Obese adults with excess visceral fat (fat located inside the abdominal cavity, around the body's internal organs) and biomarkers of insulin resistance had an associated increased risk for the development of type 2 diabetes mellitus, while obese individuals with higher amounts of total body fat and subcutaneous fat (underneath the skin) did not have this increased risk, according to a study in the September 19 issue of JAMA, and theme issue on obesity.

20 Sep 2012

High fructose corn syrup consumption alone not responsible for obesity epidemic

A new article published today in International Journal of Obesity found there is no evidence to suggest the current obesity epidemic in the United States can be specifically blamed on consumption of high fructose corn syrup (HFCS).

19 Sep 2012

Adolescent menstrual disorders linked to hyperandrogenemia

Menstrual disorders in adolescence are associated with an increased risk for hyperandrogenemia, research shows.

19 Sep 2012

Children can largely benefit from 40 minutes of daily, vigorous physical activity

Twenty minutes of daily, vigorous physical activity over just three months can reduce a child's risk of diabetes as well as his total body fat - including dangerous, deep abdominal fat - but 40 minutes works even better, researchers report.

19 Sep 2012

Obese individuals with excess visceral fat more likely to develop type 2 diabetes

Obese individuals with excess visceral fat (abdominal fat that surrounds the body-s internal organs) have an increased risk for the development of Type 2 diabetes, according to a new study by researchers at UT Southwestern Medical Center. By contrast, persons with excess abdominal subcutaneous fat (fat underneath the skin) were not at higher risk for the onset of diabetes.

19 Sep 2012

Diet, lack of AgRP-neurons can lead to obesity and diabetes

The absence of a specific type of neuron in the brain can lead to obesity and diabetes in mice report researchers in The EMBO Journal. The outcome, however, depends on the type of diet that the animals are fed.

19 Sep 2012

Modifying fat intake during pregnancy benefits children regardless of mother's size

If you are overweight and pregnant, your baby isn't destined to a life of obesity after all, according to a new research report published online in The FASEB Journal. In the report, a team of U.S. scientists show that modifying fat intake during pregnancy to a moderate level is enough to benefit the child regardless of the mother's size.

17 Sep 2012

Risks of antidiabetic drug substantially overrated for patients with reduced kidney function

The antidiabetic drug metformin is not prescribed for patients with reduced kidney function because the risk of adverse effects has been regarded as unacceptably high. A study at Sahlgrenska Academy, University of Gothenburg, Sweden, has found that the risks have been substantially overrated. As a result, many more patients with diabetes may be able to enjoy the benefits of the medication.

17 Sep 2012

MIT engineers use ultrasound waves to enhance permeability of skin to drugs

Using ultrasound waves, MIT engineers have found a way to enhance the permeability of skin to drugs, making transdermal drug delivery more efficient. This technology could pave the way for noninvasive drug delivery or needle-free vaccinations, according to the researchers.

15 Sep 2012

Pancreatic B-cell dedifferentiation leads to decline in insulin production in type 2 diabetes

Scientists generally think that reduced insulin production by the pancreas, a hallmark of type 2 diabetes, is due to the death of the organ's beta cells. However, a new study by Columbia University Medical Center (CUMC) researchers shows that beta cells do not die but instead revert to a more fundamental, undifferentiated cell type.

15 Sep 2012

Lilly, Boehringer Ingelheim announce availability of My Well Planner for adults with type 2 diabetes

Boehringer Ingelheim Pharmaceuticals, Inc. and Eli Lilly and Company today announce the availability of a new online program offering customized educational content to help adults with type 2 diabetes make simple lifestyle changes to improve their health.

14 Sep 2012

Dual role of ghrelin in anxiety behavior is context-dependent

Ghrelin is a hormone released by the lining of the stomach that promotes feeding behavior. Decreasing ghrelin levels could potentially help combat obesity -- in fact, a vaccine that lowers ghrelin levels in order to reduce appetite is being studied as a treatment for obesity.

14 Sep 2012

Hyperuricemia associated with more severe hepatic ATP depletion in response to fructose intake

Obese patients with type 2 diabetes who consume higher amounts of fructose display reduced levels of liver adenosine triphosphate (ATP)—a compound involved in the energy transfer between cells.

14 Sep 2012

Biodel initiates BIOD-123 Phase 2 trial in Type 1 diabetes

Biodel Inc. today announced the initiation of a Phase 2 clinical trial of its proprietary recombinant insulin (RHI)-based ultra-rapid-acting mealtime insulin candidate, BIOD-123.

13 Sep 2012

Angiopoietin-like protein 2 level linked to incident diabetes

Elevated angiopoietin-like protein 2 levels are associated with the development of Type 2 diabetes, show findings from a Japanese study.

12 Sep 2012

Exercise and health: An interview with Professor Karim Khan

I’ll quote from the ‘7 investments’ document (see below) as I don’t believe we need to reinvent the wheel to argue for the benefits of exercise. I am very keen to move to the issue of ‘how can we help people exercise’. But for the record:

12 Sep 2012

Electronic jewelry for health

Bracelets and amulets are in the works at Dartmouth's Institute for Security, Technology, and Society (ISTS). Rather than items of mere adornment, the scientists and engineers are constructing personal mobile health (mHealth) devices-highly functional jewelry, as it were.

12 Sep 2012

Latinos more likely to store fat in the pancreas and develop type 2 diabetes

Latinos are more likely to store fat in the pancreas and are less able to compensate by excreting additional insulin, a Cedars-Sinai study shows.

12 Sep 2012

Glucose News and Research

MiR-34a plays a key role in obesity

Tight glycemic control does not reduce infection rate after pediatric cardiac surgery

Obese adults with excess visceral fat, biomarkers of insulin resistance more likely to develop diabetes

High fructose corn syrup consumption alone not responsible for obesity epidemic

Adolescent menstrual disorders linked to hyperandrogenemia

Children can largely benefit from 40 minutes of daily, vigorous physical activity

Obese individuals with excess visceral fat more likely to develop type 2 diabetes

Diet, lack of AgRP-neurons can lead to obesity and diabetes

Modifying fat intake during pregnancy benefits children regardless of mother's size

Risks of antidiabetic drug substantially overrated for patients with reduced kidney function

MIT engineers use ultrasound waves to enhance permeability of skin to drugs

Pancreatic B-cell dedifferentiation leads to decline in insulin production in type 2 diabetes

Lilly, Boehringer Ingelheim announce availability of My Well Planner for adults with type 2 diabetes

Dual role of ghrelin in anxiety behavior is context-dependent

Hyperuricemia associated with more severe hepatic ATP depletion in response to fructose intake

Biodel initiates BIOD-123 Phase 2 trial in Type 1 diabetes

Angiopoietin-like protein 2 level linked to incident diabetes

Exercise and health: An interview with Professor Karim Khan

Electronic jewelry for health

Latinos more likely to store fat in the pancreas and develop type 2 diabetes

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

Latest News