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New study shows how the immune system regulates gut fungal population

Immune cells that process food and bacterial antigens in the intestines control the intestinal population of fungi, according to a new study from Weill Cornell Medicine scientists.

11 Jan 2018

Company-sponsored CRISPR clinical studies to begin in 2018

This year could be a defining one for CRISPR, the gene editing technique, which has been hailed as an important breakthrough in laboratory research.

10 Jan 2018

Stress accelerates development of pancreatic cancer, study shows

A new study shows that stress accelerates the development of pancreatic cancer by triggering the release of "fight-or-flight" hormones. Beta-blockers--commonly used medications that inhibit these hormones--were found to increase survival in a mouse model of the disease.

10 Jan 2018

UC scientists identify protein that acts as mediator of HER2-driven breast cancer

Researchers at the University of Cincinnati College of Medicine have identified for the first time that the estrogen receptor-binding protein MED1 is a critical mediator of HER2-driven breast cancer, identifying it as a potential therapeutic target.

9 Jan 2018

Researchers discover mutations in a gene related to obesity

Researchers have discovered mutations in a gene related to obesity, offering new treatment possibilities in the fight against the global epidemic.

8 Jan 2018

Study finds a cellular mechanism that protects plant genes from impacts of mutation

According to a new study conducted at the University of Oxford, a cellular mechanism termed DNA mismatch repair (MMR), preferentially protects plant genes from the damaging impacts of mutation.

8 Jan 2018

Sangamo and Pfizer partner for development of new zinc finger protein gene therapy to treat ALS

Sangamo Therapeutics, Inc. and Pfizer Inc. today announced a collaboration for the development of a potential gene therapy using zinc finger protein transcription factors (ZFP-TFs) to treat amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD) linked to mutations of the C9ORF72 gene.

8 Jan 2018

Cellular mechanism protects genes from damaging effects of mutation

Researchers at the University of Oxford have discovered that a cellular mechanism preferentially protects plant genes from the damaging effects of mutation.

5 Jan 2018

MGH study points toward potential strategy for treating X-linked disorders

A study from a team of Massachusetts General Hospital (MGH) investigators points toward a potential strategy for treating X-linked disorders - those caused by mutations in the X chromosome - in females.

4 Jan 2018

Discovery of potential biomarker for Huntington's disease may help postpone disease onset

A new discovery of a potential biomarker for Huntington's disease (HD) could mean a more effective way of evaluating the effectiveness of treatments for this neurological disease.

2 Jan 2018

UAB study shows missense mutations as key risk factor for severe symptoms of neurofibromatosis type 1

Research led by Ludwine Messiaen, Ph.D., professor of genetics at the University of Alabama at Birmingham, shows that missense mutations in a cluster of just five codons in the NF1 gene are an important risk factor for severe symptoms of the genetic disease neurofibromatosis type 1.

28 Dec 2017

Research clarifies role of zinc transport mechanism in onset of obstructive pulmonary diseases

Obstructive pulmonary disease is a collective term for refractory respiratory diseases with chronic airway inflammation and excessive mucus retention that are accompanied by airway obstruction.

28 Dec 2017

$Study uncovers genomic targets in refractory neuroblastoma$

Mutation News and Research

New study shows how the immune system regulates gut fungal population

Company-sponsored CRISPR clinical studies to begin in 2018

Stress accelerates development of pancreatic cancer, study shows

UC scientists identify protein that acts as mediator of HER2-driven breast cancer

Researchers discover mutations in a gene related to obesity

Study finds a cellular mechanism that protects plant genes from impacts of mutation

Sangamo and Pfizer partner for development of new zinc finger protein gene therapy to treat ALS

Cellular mechanism protects genes from damaging effects of mutation

MGH study points toward potential strategy for treating X-linked disorders

Discovery of potential biomarker for Huntington's disease may help postpone disease onset

UAB study shows missense mutations as key risk factor for severe symptoms of neurofibromatosis type 1

Research clarifies role of zinc transport mechanism in onset of obstructive pulmonary diseases

Study uncovers genomic targets in refractory neuroblastoma

Novartis announces FDA approval of its first and only CML therapy with TFR data in product label

Scientists elucidate why exercise slows progression of Parkinson's disease

Study suggests new target to treat prostate cancer

Researchers use a gene-editing complex to preserve hearing in animal model of progressive deafness

Genome editing approach prevents progressive hearing loss in animals

Gene editing shows promise to help people at risk of hearing loss

Japanese researchers use pluripotent stem cells to reproduce higher-order kidney structures

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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