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Study sheds new light on key cellular processes involved in Parkinson's disease progression

In a study published in Nature Communications, investigators at Beth Israel Deaconess Medical Center (BIDMC) shed new light on key cellular processes involved in the progression of Parkinson's disease (PD).

15 Nov 2023

$3.9 million NIH grant supports research on the Effects of integrated palliative care on Parkinson’s, related dementia

A five-year, $3.9 million grant to study the effects of integrated palliative care on health service outcomes and disparities in Parkinson's disease and Parkinson's disease dementia has been awarded to UTHealth Houston and other institutions by the National Institute of Neurological Disorders and Stroke, part of the National Institutes of Health.

15 Nov 2023

Study sheds light on specific variants responsible for rare and serious disorder

Many disorders are caused by genetic variants; to make matters worse, the genetic origin of most disorders remains unknown.

15 Nov 2023

Stand Up To Cancer unveils new gastroesophageal cancer research teams and awards

Stand Up To Cancer (SU2C) today announced three Research Teams focused on bringing new therapies to clinical trials for the treatment of gastroesophageal cancer (GEC).

15 Nov 2023

CVD-21: A novel instrument for predicting and monitoring cardiovascular disease

Researchers at Uppsala University have developed an instrument that makes it possible to measure 21 biomarkers for cardiovascular disease simultaneously with great precision by means of a simple blood test.

15 Nov 2023

Immune response that protects against infections also drives HIV latency

An immune response that likely evolved to help fight infections appears to be the mechanism that drives human immunodeficiency virus (HIV) into a latent state, lurking in cells only to erupt anew, researchers at Duke Health report.

15 Nov 2023

Investigating the link between gut inflammation, aging, and Alzheimer's disease

A recent study in discusses how gut inflammation is associated with age and Alzheimer's disease.

15 Nov 2023

Breakthrough study: inhibiting USP30 gene offers hope in treating Parkinson’s disease

Whether USP30 inhibition can serve as a disease-modifying therapy for Parkinson's disease (PD).

15 Nov 2023

Cannabis shows promise in easing endometriosis pain, new research suggests

The Journal of Clinical Medicine review explores cannabis as a self-management strategy for endometriosis pain, revealing its potential to reduce gut inflammation and improve gut permeability, thereby alleviating bloating and suppressing pain through interactions with the endocannabinoid system and gut microbiota.

14 Nov 2023

Review sheds light on the complex challenge of diagnosing and managing cow's milk allergy in children

The Nutrients journal review highlights the challenges in diagnosing and managing Cow's Milk Allergy (CMA) in children, emphasizing the discrepancy between clinical guidelines and actual practice, and the need for improved strategies in prevention and management.

14 Nov 2023

Microglia found to play crucial role in early human brain development

An international team of scientists has uncovered the vital role of microglia, the immune cells in the brain that acts as its dedicated defense team, in early human brain development.

14 Nov 2023

Novel cancer immunotherapy compound degrades an enzyme found in cancer cells and T cells

Researchers in Purdue University's College of Pharmacy are leveraging the dual roles played by an enzyme found in both cancer cells and T cells to create a novel cancer immunotherapy compound.

14 Nov 2023

Placental inflammation's role in adult depression and heart disease

An expression signature related to inflammation expressed in Hofbauer cells in the placenta, calculating polygenic risk scores to predict its expression.

14 Nov 2023

Study reveals no neuroinflammation in long COVID patients with neuropsychiatric symptoms

In a JAMA Network Open study, researchers found no evidence of neuroinflammation or blood-brain barrier dysfunction in cerebrospinal fluid markers of individuals with post-COVID-19 condition and neuropsychiatric symptoms compared to controls. The study, which assessed cytokines, chemokines, and neuroinflammation markers, suggests that persistent central nervous system immune activation may not be the primary driver of neurological long COVID symptoms.

13 Nov 2023

"Christchurch mutation" can block detrimental effects of Alzheimer’s risk factor

Researchers at Gladstone Institutes have discovered that a rare genetic variant known as the "Christchurch mutation" can block detrimental effects of apolipoprotein E4, the best-established risk factor for the most common form of Alzheimer's disease.

13 Nov 2023

Recaticimab injection every 1-3 months may safely lower bad cholesterol

A new PCSK9 inhibitor (recaticimab) injected every one to three months may work safely and provide more flexible dosing to lower cholesterol, according to late-breaking science presented today at the American Heart Association's Scientific Sessions 2023.

13 Nov 2023

Researchers encourage flexible approach to blood transfusion decisions for heart attack patients with anemia

A National Institutes of Health-supported study found that the type of transfusion approach used to support adults who developed anemia after a heart attack did not make a significant difference in their likelihood of having another heart attack or dying within 30 days.

13 Nov 2023

CRISPR-based gene-editing therapy could offer hope for people with inherited high LDL cholesterol

A single infusion of a CRISPR-based gene-editing therapy significantly reduced low-density lipoprotein cholesterol (LDL, the "bad cholesterol") in people who carry one gene for the inherited condition that results in very high LDL cholesterol levels and a high risk of heart attack at an early age, according to late-breaking science presented today at the American Heart Association's Scientific Sessions 2023.

13 Nov 2023

Study sheds light on role of antibodies in vaccine protection against COVID-19 variants

Efforts to contain the Covid-19 pandemic have largely focused on vaccine development and deployment. But how exactly do our immune systems respond to COVID-19 vaccines?

13 Nov 2023

NanoSyrinx appoints Anthony Johnson as Non-Executive Director

Appointment of Big Pharma executive strengthens leadership team to drive ambitious growth strategy.

From NanoSyrinx 13 Nov 2023

Protein C News and Research

Study sheds new light on key cellular processes involved in Parkinson's disease progression

$3.9 million NIH grant supports research on the Effects of integrated palliative care on Parkinson’s, related dementia

Study sheds light on specific variants responsible for rare and serious disorder

Stand Up To Cancer unveils new gastroesophageal cancer research teams and awards

CVD-21: A novel instrument for predicting and monitoring cardiovascular disease

Immune response that protects against infections also drives HIV latency

Investigating the link between gut inflammation, aging, and Alzheimer's disease

Breakthrough study: inhibiting USP30 gene offers hope in treating Parkinson’s disease

Cannabis shows promise in easing endometriosis pain, new research suggests

Review sheds light on the complex challenge of diagnosing and managing cow's milk allergy in children

Microglia found to play crucial role in early human brain development

Novel cancer immunotherapy compound degrades an enzyme found in cancer cells and T cells

Placental inflammation's role in adult depression and heart disease

Study reveals no neuroinflammation in long COVID patients with neuropsychiatric symptoms

"Christchurch mutation" can block detrimental effects of Alzheimer’s risk factor

Recaticimab injection every 1-3 months may safely lower bad cholesterol

Researchers encourage flexible approach to blood transfusion decisions for heart attack patients with anemia

CRISPR-based gene-editing therapy could offer hope for people with inherited high LDL cholesterol

Study sheds light on role of antibodies in vaccine protection against COVID-19 variants

NanoSyrinx appoints Anthony Johnson as Non-Executive Director

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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