Clinical Trial News and Research

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Study tests neuromuscular electrostimulation effects on hand motor recovery in older stroke patients

The University of Valencia, in collaboration with FISABIO and the Doctor Peset University Hospital, has conducted a randomised clinical trial comparing the effects of two neuromuscular electrostimulation (EENM) protocols with different frequencies on the motor impairment of the hand in older patients after a stroke.

14 Jul 2021

Full intensity heparin has value in treating hospitalized COVID-19 patients

Results from the RAPID clinical trial suggest heparin may lower the risk of death from moderate COVID-19 infection by 78%. Heparin also significantly increased the number of days patients went without ventilation or requiring organ support.

14 Jul 2021

Drug combination found to be safe and effective in malignant peritoneal mesothelioma patients

A phase II study led by researchers from The University of Texas MD Anderson Cancer Center found that treatment with atezolizumab and bevacizumab was well-tolerated and resulted in a 40% objective response rate in patients with advanced malignant peritoneal mesothelioma, a rare cancer in the lining of the abdomen.

14 Jul 2021

Lott donates $600,000 to the Zero Childhood Cancer Program

Today we'd like to say a big thank you to the Lott for their generous donation of $600,000 to the Zero Childhood Cancer Program.

14 Jul 2021

New treatment that uses 3D printed implants could bring relief to knee osteoarthritis sufferers

Pioneering 'printed metal' procedure to create bespoke treatment for early knee osteoarthritis set to be trialled in the UK following MHRA approval.

14 Jul 2021

Dying patients with rare diseases struggle to get experimental therapies

At 15, Autumn Fuernisen is dying. She was diagnosed at age 11 with a rare degenerative brain disorder that has no known cure or way to slow it down: juvenile-onset Huntington's disease.

14 Jul 2021

New study focuses on personalized therapies for people with severe asthma

A new phase 2 clinical trial of multiple therapies for severe asthma is underway in Northeast Ohio, with a focus on personalized therapies based on genetics, family history, lifestyle and environmental factors.

13 Jul 2021

Could aspirin intake reduce mortality risk in COVID-19 patients?

Scientists from the Michigan State University, USA, have conducted a systematic review and meta-analysis to compare mortality rate in coronavirus disease 2019 (COVID-19) patients who are aspirin users or non-users. The Findings reveal that the use of aspirin is associated with a significant reduction in overall and in-hospital mortality rates.

13 Jul 2021

New approach that uses machine learning could transform drug development

Writing in the July 12, 2021 online issue of Nature Communications, researchers at University of California San Diego School of Medicine describe a new approach that uses machine learning to hunt for disease targets and then predicts whether a drug is likely to receive FDA approval.

12 Jul 2021

Study: Diet rich in fermented foods boosts microbial diversity, decreases inflammation

A diet rich in fermented foods enhances the diversity of gut microbes and decreases molecular signs of inflammation, according to researchers at the Stanford School of Medicine.

12 Jul 2021

mRNA-based COVID-19 vaccine CV07050101 demonstrates limited immunogenicity in non-human primates

Scientists from the US and Germany have recently evaluated the efficacy of an mRNA-based COVID-19 vaccine candidate, CV07050101, in inducing humoral and cellular immune responses in non-human primates. The study reveals that prime-boost immunization with the vaccine candidate induces only limited immunity against SARS-CoV-2.

12 Jul 2021

What is behind the inconsistent results of COVID-19 clinical trials?

“Most clinical studies of antiviral drugs for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) have failed to observe a statistically significant effect, which may be due to poor designs of clinical trials.”

12 Jul 2021

Pfizer aims to implement boosters and a new vaccine based on SARS-CoV-2 Delta variant

The drugmaker Pfizer, one of the companies behind the Pfizer-BioNTech vaccine, or BNT162b2, awaits the green light to develop a COVID-19 booster shot that can protect against emerging variants. Pfizer’s COVID-19 vaccine has been shown to be 95% effective in an ongoing large-scale clinical trial against the original SARS-CoV-2 strain.

11 Jul 2021

Doctors weigh pros and cons of prescribing hot-button Alzheimer’s drug

As physicians and health policy experts debate the merits of Aduhelm, the first new drug for Alzheimer's disease approved in 18 years, patients want to know: "Will this medication help me — and how much?"

9 Jul 2021

Repurposed drugs for COVID-19 treatment identified through virtual screening and cell-based assays

A joint research group from KAIST and Institut Pasteur Korea has identified repurposed drugs for COVID-19 treatment through virtual screening and cell-based assays.

8 Jul 2021

Stroke treatment can have dire consequences when kidney function is low

Stroke and chronic kidney disease are both difficult to handle in their own rights, but having a stroke when your kidneys are already poor is more than just double the trouble.

8 Jul 2021

UC San Diego Health completes first surgery to implant novel device for chronic back pain

Advancing options for persons living with chronic back pain, UC San Diego Health has completed the first surgery in the nation to implant a device that uses neurostimulation in the form of electrical pulses to key nerves and muscles responsible for stabilizing the lower back.

8 Jul 2021

Mapping dengue fever hot spots can predict future outbreaks of Zika and chikungunya

Data from nine cities in Mexico confirms that identifying dengue fever “hot spots” can provide a predictive map for future outbreaks of Zika and chikungunya. All three of these viral diseases are spread by the Aedes aegypti mosquito.

7 Jul 2021

Exploring links between stress, choline deficiency, preterm births, and mental illness

In two recent articles published in Schizophrenia Bulletin, Sharon Hunter, PhD, an associate professor in the University of Colorado School of Medicine Department of Psychiatry, and M. Camille Hoffman, MD, MSc, an associate professor in the University of Colorado School of Medicine Department of Obstetrics and Gynecology, along with their research group, have uncovered a potential link between choline deficiency in Black pregnant women in the United States and increased risk of developmental and behavioral issues that can evolve into mental illness later in their children's lives.

7 Jul 2021

Study reveals the brain activity that underlies superagers' superior memory

As we age, our brains typically undergo a slow process of atrophy, causing less robust communication between various brain regions, which leads to declining memory and other cognitive functions. But a rare group of older individuals called "superagers" have been shown to learn and recall novel information as well as a 25-year-old.

7 Jul 2021

Clinical Trial News and Research

Study tests neuromuscular electrostimulation effects on hand motor recovery in older stroke patients

Full intensity heparin has value in treating hospitalized COVID-19 patients

Drug combination found to be safe and effective in malignant peritoneal mesothelioma patients

Lott donates $600,000 to the Zero Childhood Cancer Program

New treatment that uses 3D printed implants could bring relief to knee osteoarthritis sufferers

Dying patients with rare diseases struggle to get experimental therapies

New study focuses on personalized therapies for people with severe asthma

Could aspirin intake reduce mortality risk in COVID-19 patients?

New approach that uses machine learning could transform drug development

Study: Diet rich in fermented foods boosts microbial diversity, decreases inflammation

mRNA-based COVID-19 vaccine CV07050101 demonstrates limited immunogenicity in non-human primates

What is behind the inconsistent results of COVID-19 clinical trials?

Pfizer aims to implement boosters and a new vaccine based on SARS-CoV-2 Delta variant

Doctors weigh pros and cons of prescribing hot-button Alzheimer’s drug

Repurposed drugs for COVID-19 treatment identified through virtual screening and cell-based assays

Stroke treatment can have dire consequences when kidney function is low

UC San Diego Health completes first surgery to implant novel device for chronic back pain

Mapping dengue fever hot spots can predict future outbreaks of Zika and chikungunya

Exploring links between stress, choline deficiency, preterm births, and mental illness

Study reveals the brain activity that underlies superagers' superior memory

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