Sclerosis News and Research

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Researchers find new way to transplant new blood-forming stem cells into bone marrow of mice

Researchers at the Stanford University School of Medicine have taken a small but significant step, in mouse studies, toward the goal of transplanting adult stem cells to create a new immune system for people with autoimmune or genetic blood diseases.

22 Nov 2007

New study finds blood-spinal cord barrier compromised in mice with ALS

The blood-spinal cord barrier is functionally impaired in areas of motor neuron damage in mice modeling amyotrophic lateral sclerosis (ALS), report researchers at the University of South Florida Center for Aging and Brain Repair.

21 Nov 2007

Migraine sufferers found to have brain differences

According to new research from the U.S., migraine sufferers have structural differences in the part of the brain that deals with pain.

20 Nov 2007

People with migraines have differences in cortex area of the brain

People with migraines have differences in an area of the brain that helps process sensory information, including pain, according to a study published in the November 20, 2007, issue of Neurology, the medical journal of the American Academy of Neurology.

19 Nov 2007

Blood clotting protein fibrin plays a role in rheumatoid arthritis

Researchers at Cincinnati Children's have issued the first study showing that a protein normally involved in blood clotting (fibrin), also plays an important role in the inflammatory response and development of rheumatoid arthritis.

19 Nov 2007

Avicena receives U.S. patent for compounds to treat Lou Gehrig's disease

Avicena Group, Inc. has announced that the United States Patent and Trademark Office (USPTO) has granted the Company U.S. Patent #7,285,573 for the use of the Company's proprietary drug candidates for the treatment of amyotrophic lateral sclerosis ("ALS" or "Lou Gehrig's Disease").

14 Nov 2007

Researchers image a biomarker of neurogenesis

Mirjana Maletic-Savatic, M.D., Ph.D, and co-investigators from Stony Brook University Medical Center, Brookhaven National Laboratory and Cold Spring Harbor Laboratory have discovered a way to image a biomarker of neural stem and progenitor cells (NPCs) in the living human brain.

13 Nov 2007

New target for MS treatment found using old drug

A drug currently used to treat high blood pressure and heart failure has been found to reduce the symptoms of multiple sclerosis in mice.

13 Nov 2007

Anti-inflammation molecule helps fight MS-like disease

An immune system messenger molecule that normally helps quiet inflammation could be an effective tool against multiple sclerosis (MS). Neurology researchers led by Abdolmohamad Rostami, M.D., Ph.D., professor and chair of the Department of Neurology at Jefferson Medical College of Thomas Jefferson University and the Jefferson Hospital for Neuroscience in Philadelphia, have found that the protein interkeukin-27 (IL-27) helped block the onset or reverse symptoms in animals with an MS-like disease.

13 Nov 2007

Research reveals critical knowledge about the nervous system

Uncover the neural communication links involved in myelination, the process of protecting a nerve's axon, and it may become possible to reverse the breakdown of the nervous system's electrical transmissions in such disorders as multiple sclerosis, spinal cord injuries, diabetes and cancers of the nervous system.

6 Nov 2007

Aggregation propensity, amyloid peptide toxicity and Alzheimer disease

Cells have evolved multiple mechanisms to ensure proper folding, but a number of molecular and biophysical events - such as changes in pH or temperature, mutations, and oxidation - can disrupt a protein's native shape.

31 Oct 2007

Risk factors that may contribute to the onset of Amyotrophic Lateral Sclerosis

Researchers in Rensselaer Polytechnic Institute's Social and Behavioral Research Lab (SBRL) are leading a study to investigate potential environmental, lifestyle, and medical variables that may contribute to the onset of Amyotrophic Lateral Sclerosis (ALS).

29 Oct 2007

Therapeutic gene expression can be sustainable for 1 year

Researchers at the Board of Governors Gene Therapeutics Research Institute at Cedars-Sinai Medical Center have shown for the first time that it is possible to sustain therapeutic gene expression in the central nervous system for up to a year, even in the presence of an anti-viral immune response mechanism that is normally present in humans.

28 Oct 2007

Extensive review supports safety of silicone breast implants

An exhaustive review - the first in almost a decade, including the latest evidence on the health effects of silicone breast implants - finds no increase in the risk of cancers, connective tissue diseases, or other serious chronic diseases.

28 Oct 2007

FDA warns about 'stay awake drug' Provigil

The U.S. Food and Drug Administration (FDA) has issued a warning in connection with the drug Provigil because of dangerous side effects.

28 Oct 2007

Scientists discover new causes for neurodegeneration

Diseases that cause neurons to break-down, such as Alzheimer's, Multiple Sclerosis and Creutzfeldt-Jakob disease (Mad Cow Disease), continue to be elusive to scientists and resistant to treatments.

25 Oct 2007

Synthetic form of THC is an effective anti-depressant at low doses

A new neurobiological study has found that a synthetic form of THC, the active ingredient in cannabis, is an effective anti-depressant at low doses.

24 Oct 2007

Discovery of two genes linked to a disabling form of arthritis called ankylosing spondylitis

An international team of researchers led by a Fred Hutchinson Cancer Research Center geneticist has discovered two genes linked to a disabling form of arthritis called ankylosing spondylitis, a painful and progressive disease in which some or all of the spine's vertebrae fuse together.

22 Oct 2007

Childhood epilepsy research offers new hope for seizure control

Scientists still do not know what causes epileptic seizures, but researchers from Melbourne's Howard Florey Institute are one step closer to solving this puzzle with the help of their newly developed genetically modified epileptic mouse.

18 Oct 2007

Phase II map of human genetic variation

The International HapMap Consortium today published analyses of its second-generation map of human genetic variation, which contains three times more markers than the initial version unveiled in 2005.

18 Oct 2007