immunity News and Research

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Comparison of immunological profiles of SARS-CoV-2 variants

Mutations to the spike protein and receptor-binding domain are responsible for these changes in immunogenic profile, and in a paper recently uploaded to the open access journal Antibiotics by Ambrose et al. (May 6th, 2021) these mutations are correlated with various disease parameters by in silico methods, finding that particular features are responsible for the increased infectiousness and lesser disease severity observed in these lineages.

6 Jun 2021

Standardizable assay detects T cell responses to SARS-CoV-2 infection

Researchers in the UK have developed a high-throughput standardizable assay that accurately detects T cell responses to infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

6 Jun 2021

Georgia State professor receives federal grant to study seasonal and universal vaccination in elderly populations

Dr. Sang-Moo Kang, professor in the Institute for Biomedical Sciences at Georgia State University, has received a five-year, $2.7 million federal grant to study seasonal and universal vaccination in elderly populations with pre-existing immunity to influenza viruses.

5 Jun 2021

Maternal SARS-CoV-2 infection imprints immune response in the newborn

A new bioRxiv* preprint reports the immunological footprint in the newborn left by maternal infection with SARS-CoV-2 during pregnancy.

4 Jun 2021

Risk of SARS-CoV-2 spread to bats

A recent bioRxiv* preprint offers a powerful risk assessment approach to estimate the risk of bat exposure to SARS-CoV-2 from humans during their interactions in the wild.

4 Jun 2021

World Health Organization simplifies names of SARS-CoV-2 variants

Now, the World Health Organization (WHO) has assigned simple and easy-to-say labels for key variants of SARS-CoV-2 using letters of the Greek alphabet. The health agency selected these labels after a thorough review of many potential naming systems.

4 Jun 2021

Researchers identify a novel link between aging, metabolism and anti-cancer T-cell function

MUSC Hollings Cancer Center researchers are finding solutions to the aging-related changes that reduce anti-cancer immunity. Besim Ogretmen, Ph.D., and colleagues found a novel link between aging, metabolism and anti-cancer T-cell function. Their work, published in Cell Reports, sheds light on an important pathway that cannot be ignored during cancer treatment.

4 Jun 2021

Study says COVID-19 vaccines passports will likely reduce inclination to accept vaccines

Now, a new study published on medRxiv* preprint server focuses on the quantitative evaluation of the impact of the implementation of vaccine passports for domestic and international travel.

4 Jun 2021

New research focuses on cow's milk as a possible source of COVID-19 control

Physiologically, milk contains biocomponents that are highly protective against infections. In light of this, the AGR-149-Infectious Diseases group at the University of Cordoba's Department of Animal Health is doing research that focuses on cow's milk as a possible source of Covid-19 control. The results have been published, partially, in the journal Frontiers in Immunology.

4 Jun 2021

People who received Pfizer-Biontech vaccine have lower antibody levels targeting the delta variant

Levels of antibodies in the blood of vaccinated people that are able to recognise and fight the new SARS-CoV-2 Delta variant first discovered in India (B.1.617.2) are on average lower than those against previously circulating variants in the UK, according to new laboratory data from the Francis Crick Institute and the National Institute for Health Research (NIHR) UCLH Biomedical Research Centre, published today (Thursday) as a Research letter in The Lancet.

4 Jun 2021

Research opens alternative therapeutic avenues for treatment of chronic pain

Building on previous findings, scientists have demonstrated that conolidine interacts with the newly identified opioid receptor ACKR3/CXCR7.

3 Jun 2021

Study explores COVID-19 vaccine beliefs and behaviors among college students

A recent study conducted by researchers at Pennsylvania State University in the US explored the beliefs and attitudes of students about vaccination in general and the COVID-19 vaccines in particular.

3 Jun 2021

COVID-19 mortality in Israel and Europe after vaccination

The study, which appeared on the pre-print server, medRxiv*, confirms the potent efficacy of COVID-19 vaccination based on real-life public data in terms of protection against death.

2 Jun 2021

Predictors of COVID vaccination uptake in the U.S.

A recent preprint research paper posted to the medRxiv server describes the changing patterns of vaccine uptake in the USA and offers short-term forecasts to help create strategies of vaccine supply as required.

2 Jun 2021

E484K mutation may confer immune evasion capability on UK variant of SARS-CoV-2

A new medRxiv* preprint reports the immunomodulatory effect of the E484K mutation newly acquired by the United Kingdom (U.K.) variant.

2 Jun 2021

Large-scale expansion of spike-reactive T cells feasible after COVID-19 vaccination

A new bioRxiv* preprint reports on the successful use of a protocol to expand SARS-CoV-2-reactive T-cells a thousand-fold.

2 Jun 2021

New study sheds light on why many COVID-19 patients suffer from hypoxia

A new study published in the journal Stem Cell Reports by University of Alberta researchers is shedding light on why many COVID-19 patients, even those not in hospital, are suffering from hypoxia--a potentially dangerous condition in which there is decreased oxygenation in the body's tissues.

2 Jun 2021

Novel SARS-CoV-2 variants partially resistant to infection- and vaccine-induced immunity, study finds

A recent study conducted by a team of scientists in the Netherlands has revealed that while severely affected hospitalized COVID-19 patients and vaccinated individuals are capable of neutralizing the B.1.1.7, B.1.351, and P.1 variants of SARS-CoV-2, a significant proportion of non-hospitalized patients with less severe COVID-19 remain susceptible to these viral variants.

2 Jun 2021

New vaccine candidate with RBD and N protein targets protects against SARS-CoV-2 in preclinical trials

A recent study published in the journal Science Advances, explores the immunization of RBD with the P2 epitope of tetanus toxoid, to enhance its immunogenicity, and also tests the benefit of N protein in the vaccine.

2 Jun 2021

Can immunity form and interaction with seasonal coronaviruses influence SARS-CoV-2 epidemiology?

A new study hypothesizes that cross-protection from seasonal epidemics of HCoVs could not only affect SARS-CoV-2 transmission but also protect children from the disease.

2 Jun 2021

immunity News and Research

Comparison of immunological profiles of SARS-CoV-2 variants

Standardizable assay detects T cell responses to SARS-CoV-2 infection

Georgia State professor receives federal grant to study seasonal and universal vaccination in elderly populations

Maternal SARS-CoV-2 infection imprints immune response in the newborn

Risk of SARS-CoV-2 spread to bats

World Health Organization simplifies names of SARS-CoV-2 variants

Researchers identify a novel link between aging, metabolism and anti-cancer T-cell function

Study says COVID-19 vaccines passports will likely reduce inclination to accept vaccines

New research focuses on cow's milk as a possible source of COVID-19 control

People who received Pfizer-Biontech vaccine have lower antibody levels targeting the delta variant

Research opens alternative therapeutic avenues for treatment of chronic pain

Study explores COVID-19 vaccine beliefs and behaviors among college students

COVID-19 mortality in Israel and Europe after vaccination

Predictors of COVID vaccination uptake in the U.S.

E484K mutation may confer immune evasion capability on UK variant of SARS-CoV-2

Large-scale expansion of spike-reactive T cells feasible after COVID-19 vaccination

New study sheds light on why many COVID-19 patients suffer from hypoxia

Novel SARS-CoV-2 variants partially resistant to infection- and vaccine-induced immunity, study finds

New vaccine candidate with RBD and N protein targets protects against SARS-CoV-2 in preclinical trials

Can immunity form and interaction with seasonal coronaviruses influence SARS-CoV-2 epidemiology?

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