Cholesterol News and Research

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Cholesterol is a waxy, fat-like substance made in the liver, and found in the blood and in all cells of the body. Cholesterol is important for good health and is needed for making cell walls, tissues, hormones, vitamin D, and bile acid.

Buck Institute finds link between ApoE4 and anti-aging protein targeted by resveratrol in red wine

he major genetic risk factor for Alzheimer's disease (AD), present in about two-thirds of people who develop the disease, is ApoE4, the cholesterol-carrying protein that about a quarter of us are born with. But one of the unsolved mysteries of AD is how ApoE4 causes the risk for the incurable, neurodegenerative disease.

22 Oct 2013

FDA approves SC formulation of Genentech's Actemra for rheumatoid arthritis

Genentech, a member of the Roche Group, today announced that the U.S. Food and Drug Administration has approved a subcutaneous formulation of Actemra (tocilizumab) for the treatment of adults with moderately to severely active rheumatoid arthritis who have used one or more disease-modifying antirheumatic drugs, such as methotrexate, that did not provide enough relief.

22 Oct 2013

Binge drinking increases atherosclerotic progression, stroke mortality risk in men

A Finnish population-based study showed that binge drinking was associated with increased atherosclerotic progression in an 11-year follow-up of middle-aged men. The progression of atherosclerosis was increased among men who consumed 6 drinks or more on one occasion.

21 Oct 2013

Hereditary high blood cholesterol overlooked and untreated worldwide

Hereditary high blood cholesterol leads to premature heart disease. It is overlooked and untreated virtually worldwide -- including in Europe. This is a major problem as the disease is dangerous for health. However, this disease is easy to diagnose and treat, according to the conclusion of a consensus report from the European Atherosclerosis Society.

21 Oct 2013

Study shows significant link between low dietary fiber intake and cardiometabolic risks

A new study published in the December issue of The American Journal of Medicine shows a significant association between low dietary fiber intake and cardiometabolic risks including metabolic syndrome, cardiovascular inflammation, and obesity.

19 Oct 2013

High-intensity interval training with Mediterranean diet counselling 'supersizes' heart health

Lifestyle programs focused on high-intensity interval training combined with nutritional counselling on the Mediterranean diet have shown dramatic results for improving the heart health of people with abdominal obesity, finds a study released at the Canadian Cardiovascular Congress.

18 Oct 2013

Hypertension during pregnancy could raise woman's lifetime risk of stroke

High blood pressure during pregnancy could dramatically raise a woman's lifetime risk of stroke, according to a study presented today at the Canadian Stroke Congress.

18 Oct 2013

'Traffic light' labels can be effective method of promoting healthier food choices

A simple, color-coded system for labeling food items in a hospital cafeteria appears to have increased customer's attention to the healthiness of their food choices, along with encouraging purchases of the most healthy items.

18 Oct 2013

Use of effective, risky drug therapies by Medicare patients varies across US

A new report from the Dartmouth Atlas Project shows that the use of both effective and risky drug therapies by Medicare patients varies widely across U.S. regions, offering further evidence that location is a key determinant in the quality and cost of the medical care that patients receive.

18 Oct 2013

Atorvastatin drug plus zoledronic acid may help treat toxoplasmosis

Researchers at the University of Georgia have discovered that a combination of two commonly prescribed drugs used to treat high cholesterol and osteoporosis may serve as the foundation of a new treatment for toxoplasmosis, a parasitic infection caused by the protozoan Toxoplasma gondii. They published their findings recently in PLOS Pathogens.

18 Oct 2013

Cardiometabolic risk high for schizophrenia patients

The risk for abdominal obesity may be increased as much as fourfold for patients with multi-episode schizophrenia compared with the rest of the population, reveal findings from a meta-analysis.

17 Oct 2013

Proteins in CSF predict cognitive impairment before onset of disease

Johns Hopkins researchers say that by measuring levels of certain proteins in cerebrospinal fluid (CSF), they can predict when people will develop the cognitive impairment associated with Alzheimer's disease years before the first symptoms of memory loss appear.

17 Oct 2013

Implementing powerful health promotion strategies can help save lives of Canadians

Canada can save lives by implementing powerful health promotion strategies, says Dr. Thomas Farley, the trail-blazing commissioner of the New York City department of health.

17 Oct 2013

Researchers find 5-fold increase in high cholesterol risk

What leads to high cholesterol? Your genes and lifestyle factors may not explain it all. A study presented today at the Canadian Cardiovascular Congress has connected some of the risk for high cholesterol in adults to their mother's cholesterol levels before she even became pregnant.

17 Oct 2013

Get With The Guidelines--Stroke hospitals provide recommended guideline-based care for patients

Award-winning Get With The Guidelines--Stroke hospitals are more likely than Primary Stroke Center certified hospitals to provide all the recommended guideline-based care for patients, according to new research in the Journal of the American Heart Association.

16 Oct 2013

Research shows inhibition of Rcan1 protein may reduce atherosclerosis in mice

Researchers of the Spanish research council (Consejo Superior de Investigaciones Cient-ficas, CSIC) and the Centro Nacional de Investigaciones Cardiovasculares (CNIC) have discovered that inhibiting the protein Rcan1 in mice reduces the burden of atherosclerosis, one of the commonest cardiovascular diseases.

16 Oct 2013

Phase 3 ODYSSEY MONO trial with alirocumab meets primary efficacy endpoint

Sanofi and Regeneron Pharmaceuticals, Inc. today announced that the Phase 3 ODYSSEY MONO trial with alirocumab, an investigational monoclonal antibody targeting PCSK9 (proprotein convertase subtilisin/kexin type 9), met its primary efficacy endpoint.

16 Oct 2013

Baylor provides AED demonstrations on how to save people who experience sudden cardiac arrest

Exiting an elevator, a man crumples to the floor just outside the elevator. You, an innocent bystander, freeze. Then, you see the glass case on the wall with the heart and lightening decal. Whether or not you reach for that case and open it is a life or death decision for the stranger lying at the elevator doors.

15 Oct 2013

Statins may increase risk of cataracts among individuals above 30 years old

According to the Centers for Disease Control and Prevention, cataracts are the number one cause of vision loss in the United States. Nearly 22 million Americans age 40 and over have cataracts, while more than half of individuals age 80 and over suffer from this condition. In a recent study released in JAMA Ophthalmology, it was confirmed that statins, which are typically prescribed to reduce cholesterol and also prevent heart disease, may cause an increased risk for cataracts among individuals ages 30 through 85.

14 Oct 2013

Patient with certain gene variation more likely to suffer cognitive decline five years after surgery

Long-term memory loss, difficulty understanding verbal or written communication or impaired ability to pay attention may still occur five years after heart surgery if a patient has a certain gene variation, according to a study presented at the ANESTHESIOLOGY 2013 annual meeting.

14 Oct 2013

Cholesterol News and Research

Further Reading

Buck Institute finds link between ApoE4 and anti-aging protein targeted by resveratrol in red wine

FDA approves SC formulation of Genentech's Actemra for rheumatoid arthritis

Binge drinking increases atherosclerotic progression, stroke mortality risk in men

Hereditary high blood cholesterol overlooked and untreated worldwide

Study shows significant link between low dietary fiber intake and cardiometabolic risks

High-intensity interval training with Mediterranean diet counselling 'supersizes' heart health

Hypertension during pregnancy could raise woman's lifetime risk of stroke

'Traffic light' labels can be effective method of promoting healthier food choices

Use of effective, risky drug therapies by Medicare patients varies across US

Atorvastatin drug plus zoledronic acid may help treat toxoplasmosis

Cardiometabolic risk high for schizophrenia patients

Proteins in CSF predict cognitive impairment before onset of disease

Implementing powerful health promotion strategies can help save lives of Canadians

Researchers find 5-fold increase in high cholesterol risk

Get With The Guidelines--Stroke hospitals provide recommended guideline-based care for patients

Research shows inhibition of Rcan1 protein may reduce atherosclerosis in mice

Phase 3 ODYSSEY MONO trial with alirocumab meets primary efficacy endpoint

Baylor provides AED demonstrations on how to save people who experience sudden cardiac arrest

Statins may increase risk of cataracts among individuals above 30 years old

Patient with certain gene variation more likely to suffer cognitive decline five years after surgery

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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