Infectious Diseases News and Research

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NIAID-supported clinical trial begins at four Vaccine and Treatment Evaluation Units

A clinical trial in which healthy adults will be deliberately infected with influenza virus under carefully controlled conditions is recruiting volunteers at four Vaccine and Treatment Evaluation Units (VTEUs) supported by NIH's National Institute of Allergy and Infectious Diseases.

24 Oct 2019

Universal influenza vaccine developed at Cornell is set for human clinical trials

A universal influenza vaccine with the potential to be longer lasting and more effective than commercially available vaccines is destined for human clinical trials, thanks to a $17.9 million grant from the National Institute of Allergy and Infectious Diseases.

24 Oct 2019

GHS Index: Not a single country fully prepared to handle epidemic or pandemic

A new Global Health Security Index released today, the first comprehensive assessment and benchmarking of health security and related capabilities across 195 countries, suggests that not a single country in the world is fully prepared to handle an epidemic or pandemic.

24 Oct 2019

Scientists find new strains of human adenovirus in Singapore

Human adenovirus (HAdV) infections in Singapore and Malaysia have caused severe respiratory disease among children and adults in recent years, but scientists still don't know whether these outbreaks are due to new or re-emerging virus strains.

24 Oct 2019

Wyss Institute joins Global Virus Network as new Center of Excellence to fight viral threats

Today, the Global Virus Network, a conglomerate of 52 "Centers of Excellence" and 9 Affiliates in 32 countries, which catalyzes collaborative research into diseases caused by every class of virus in humans and animals, announced the Wyss Institute for Biologically Inspired Engineering at Harvard University as a new Center of Excellence.

24 Oct 2019

Cooperative research center at LLNL aims to develop vaccines for chlamydia

A cooperative research center that aims to develop vaccines for chlamydia has been established by the National Institutes of Health at Lawrence Livermore National Laboratory.

24 Oct 2019

UAB researchers awarded grant to study a vaccine for gonorrhea

University of Alabama at Birmingham researchers have been awarded a three-year contract with a total potential amount of $10 million to study the efficacy of the vaccine Bexsero - already licensed to prevent meningitis - in protecting vulnerable populations from infection with the bacteria that causes gonorrhea.

23 Oct 2019

SLU research halts toxic protein linked to muscular dystrophy in animal models

There is no cure or treatment for facioscapulohumeral muscular dystrophy, an illness that starts with facial, shoulder and upper arm weakness and eventually affects nearly all skeletal muscles of those with the disease.

23 Oct 2019

Disrupting key immune regulator boosts anti-tumor immunity, enables cancer clearance

The immune system must strike an exquisite balance between vanquishing infections and cancer, while at the same time restraining its activity to avoid inadvertently attacking the body's healthy tissues and organs.

23 Oct 2019

Researchers discover conjugative plasmid that augments virulence in superbug

A recent research led by a scientist at City University of Hong Kong has discovered an easily transmitted DNA piece that can make a new type of hyper-resistant and deadly superbug become hyper-virulent quickly, posing an unprecedented threat to human health.

23 Oct 2019

E. coli superbug spreading by poor toilet hygiene, not through food

A new study published in The Lancet Infectious Diseases on October 22, 2019, says that one common superbug that causes more than 5,000 cases of food poisoning in England every year is spread not through contaminated food but through contaminated toilet surfaces.

23 Oct 2019

New collaboration aims to develop gene-based cures for sickle cell disease and HIV

The National Institutes of Health plans to invest at least $100 million over the next four years toward an audacious goal: develop affordable, gene-based cures for sickle cell disease and HIV.

23 Oct 2019

New $30M contract signed to accelerate TB vaccine development across the country

Tuberculosis (TB) is the number-one cause of death from an infectious disease in the world: In 2017, the most recent data available, 10 million people developed TB and 1.6 million died.

23 Oct 2019

Researchers assess accuracy of lateral flow urine LAM test in detecting TB in HIV-positive people

Tuberculosis (TB) causes more deaths in people living with HIV than any other disease, with more than 300,000 deaths in 2017. When detected, early TB can be treated effectively; however, people with advanced HIV are at high risk of death, often without knowing they have TB.

22 Oct 2019

Researchers receive $3.2 million NIH grant to pursue a deeper understanding of Down syndrome

Mount Sinai researchers have been awarded a $3.2 million grant from the National Institutes of Health to pursue a deeper understanding of Down syndrome, the most common genetic cause of intellectual and developmental disabilities in children and young adults, affecting more than 200,000 individuals in the United States.

22 Oct 2019

Antibiotic resistance doubles in just two decades

Antibiotic resistance poses a grave challenge to many previously curable infectious diseases. At present, antibiotic resistance is proving to increase at a much faster rate compared to the development of new therapies.

21 Oct 2019

Ebola virus vaccine still effective against the infection even in low concentrations

The Ebola virus (EBOV), variant Makona, was the causative agent of the 2014-2016 West African epidemic that took over 11,000 lives and infected nearly 30,000 people. But with the combination of globally-supported containment efforts, health experts were able to track the spread of the outbreak, as well as use precautionary and quarantine procedures.

21 Oct 2019

Neutrophil extracellular traps could cause organ damage in malaria

Malaria is one of the world's deadliest infectious diseases: a small mosquito bite delivers numerous malaria parasites into the bloodstream. The human body defends itself valiantly against the parasite, which usually results in periodic flu-like symptoms and severe fever. Severe cases of the disease are accompanied by tissue damage and result in potentially fatal organ failure.

21 Oct 2019

OPAT adherence device took top prize at IDEA Incubator competition

A device designed to improve adherence to outpatient parenteral antimicrobial therapy took top prize at the second IDEA Incubator, a competition showcasing inventions, products and devices to improve patient care for infectious diseases, which takes place during IDWeek.

18 Oct 2019

Highly diluted candidate Ebola vaccine remains fully protective against disease in macaques

A single dose of a highly diluted VSV-Ebola virus vaccine--approximately one-millionth of what is in the vaccine being used to help control the ongoing Ebola outbreak in the Democratic Republic of the Congo (DRC)--remains fully protective against disease in experimentally infected monkeys, according to National Institutes of Health scientists.

18 Oct 2019

Infectious Diseases News and Research

NIAID-supported clinical trial begins at four Vaccine and Treatment Evaluation Units

Universal influenza vaccine developed at Cornell is set for human clinical trials

GHS Index: Not a single country fully prepared to handle epidemic or pandemic

Scientists find new strains of human adenovirus in Singapore

Wyss Institute joins Global Virus Network as new Center of Excellence to fight viral threats

Cooperative research center at LLNL aims to develop vaccines for chlamydia

UAB researchers awarded grant to study a vaccine for gonorrhea

SLU research halts toxic protein linked to muscular dystrophy in animal models

Disrupting key immune regulator boosts anti-tumor immunity, enables cancer clearance

Researchers discover conjugative plasmid that augments virulence in superbug

E. coli superbug spreading by poor toilet hygiene, not through food

New collaboration aims to develop gene-based cures for sickle cell disease and HIV

New $30M contract signed to accelerate TB vaccine development across the country

Researchers assess accuracy of lateral flow urine LAM test in detecting TB in HIV-positive people

Researchers receive $3.2 million NIH grant to pursue a deeper understanding of Down syndrome

Antibiotic resistance doubles in just two decades

Ebola virus vaccine still effective against the infection even in low concentrations

Neutrophil extracellular traps could cause organ damage in malaria

OPAT adherence device took top prize at IDEA Incubator competition

Highly diluted candidate Ebola vaccine remains fully protective against disease in macaques

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