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Oligodendrocytes identified as key amyloid β producers in Alzheimer's disease

Researchers discovered that oligodendrocytes, not just neurons, produce amyloid β in Alzheimer's disease, and suppressing their activity improves disease pathology. This finding suggests new therapeutic targets for Alzheimer's treatment.

24 Jul 2024

Breakthrough gene therapy restores dystrophin protein in Duchenne muscular dystrophy

Indiana University School of Medicine researchers have made a significant breakthrough in developing a new gene therapy approach that restores full-length dystrophin protein, which could lead to new treatments for people with Duchenne muscular dystrophy (DMD).

24 Jul 2024

Proof-of-concept animal studies demonstrate a step forward in the fight against HIV

Researchers in George Mason University's Center for Infectious Disease Research (CIDR) and Tulane National Primate Research Center conducted a breakthrough proof-of-concept study in Nature's Gene Therapy that found an HIV-like virus particle that could cease the need for lifelong medications.

24 Jul 2024

Simple blood test may predict CAR-T therapy success in multiple myeloma

A simple blood test that measures the number of lymphocytes, a type of white blood cell in the body, may predict whether people who have relapsed multiple myeloma are going to respond well to CAR-T immunotherapy, according to new research from Weill Cornell Medicine, NewYork-Presbyterian, Columbia University and Icahn School of Medicine at Mount Sinai.

24 Jul 2024

AI improves breast cancer staging by analyzing chromatin images

Researchers at the Paul Scherrer Institute PSI and the Massachusetts Institute of Technology MIT are using artificial intelligence to improve the categorization of breast cancer.

24 Jul 2024

CHEST releases new clinical guideline for managing central airway obstruction

The American College of Chest Physicians (CHEST) recently released a new clinical guideline on central airway obstruction (CAO).

24 Jul 2024

Community pharmacists help close gaps in stroke prevention for Afib patients

Atrial fibrillation (Afib) is the most common heart rhythm disorder encountered in clinical practice according to Dr. Roopinder Sandhu, MD, MPH, and the leading cause of stroke in older individuals.

24 Jul 2024

Kaempferol's promise in fighting triple-negative breast cancer

Review highlights kaempferol's potential in treating triple-negative breast cancer through various anticancer mechanisms and improving chemotherapeutic efficacy.

24 Jul 2024

$ActiveHip+ enhances recovery for elderly hip fracture patients$

ActiveHip+ enhances recovery for elderly hip fracture patients

This digital solution was developed as part of a European project led by the University of Granada (UGR) and the Andalusian Health Service (SAS).

24 Jul 2024

Broken String Biosciences appoints Steve Becker as Chief Commercial Officer

Broken String Biosciences (“Broken String”), a genomics company driving development of the next generation of more precise, safe, and effective cell and gene therapies, today announced it has appointed Steve Becker as Chief Commercial Officer.

24 Jul 2024

Enterprise Therapeutics doses first person with cystic fibrosis in Phase 2 trial for novel therapy ETD001

Enterprise Therapeutics Ltd (Enterprise), a biopharmaceutical company dedicated to the discovery and development of novel therapies to improve the lives of those suffering from respiratory disease, today announced dosing of the first person with cystic fibrosis (pwCF) in its Phase 2a trial of ETD001.

24 Jul 2024

Associations between gut microbes and Alzheimer’s disease

Researchers reviewed existing data on the role of the gut microbiome in Alzheimer’s disease (AD) pathogenesis.

24 Jul 2024

Comprehensive peri-operative care guidelines address needs of transgender and gender-diverse patients

New guidance on peri-operative care of transgender and gender-diverse individuals is today published in Anaesthesia (the journal of the Association of Anaesthetists) to guide best practice to ensure the safety and dignity of transgender and gender-diverse people in the peri-operative period.

23 Jul 2024

More types of lung cells can be infected by SARS-CoV-2 than previously thought, scientists report

Scientists at Sanford Burnham Prebys, University of California San Diego and their international collaborators have reported that more types of lung cells can be infected by SARS-CoV-2 than previously thought, including those without known viral receptors.

23 Jul 2024

Financial incentives boost meal replacement therapy success in severely obese adolescents

Adolescents with severe obesity who received meal-replacement therapy plus financial incentives experienced a greater reduction in body mass index compared to those who received meal replacement therapy alone, according to recent findings published in JAMA Pediatrics.

23 Jul 2024

Exploring non-coding RNAs as regulators of notch signaling in breast cancer

Breast cancer (BC) remains one of the most challenging cancers to treat, primarily due to its heterogeneity and propensity for metastasis.

23 Jul 2024

Lario Therapeutics awarded $6M Grant from The Michael J. Fox Foundation for Parkinson’s Research

Award supports preclinical research of Lario’s CaV2.3 calcium channel inhibitors as a novel disease-modifying approach for treatment of Parkinson's disease.

23 Jul 2024

Beyond the anti-obesity benefits of glucagon-like peptide-1 drugs

The advantages of glucagon-like peptide-1 (GLP-1) medicines beyond glycemic and weight control.

23 Jul 2024

New study sheds light on irregular heartbeat risk

Two new, basic animal research studies shed light on alcohol consumption and the heart. The first study may help explain why binge drinking sometimes causes an irregular heartbeat and a possible way to prevent it. The second study investigated why alcohol may have a negative impact on heart function in women taking estrogen replacement therapy.

23 Jul 2024

Combination of sEphB4-HSA and pembrolizumab shows promise in HPV-negative EphrinB2 positive HNSCC

A new research paper was published in Oncotarget's Volume 15 on July 10, 2024, entitled, "Improved efficacy of pembrolizumab combined with soluble EphB4-albumin in HPV-negative EphrinB2 positive head neck squamous cell carcinoma."

22 Jul 2024

Therapy News and Research

Oligodendrocytes identified as key amyloid β producers in Alzheimer's disease

Breakthrough gene therapy restores dystrophin protein in Duchenne muscular dystrophy

Proof-of-concept animal studies demonstrate a step forward in the fight against HIV

Simple blood test may predict CAR-T therapy success in multiple myeloma

AI improves breast cancer staging by analyzing chromatin images

CHEST releases new clinical guideline for managing central airway obstruction

Community pharmacists help close gaps in stroke prevention for Afib patients

Kaempferol's promise in fighting triple-negative breast cancer

ActiveHip+ enhances recovery for elderly hip fracture patients

Broken String Biosciences appoints Steve Becker as Chief Commercial Officer

Enterprise Therapeutics doses first person with cystic fibrosis in Phase 2 trial for novel therapy ETD001

Associations between gut microbes and Alzheimer’s disease

Comprehensive peri-operative care guidelines address needs of transgender and gender-diverse patients

More types of lung cells can be infected by SARS-CoV-2 than previously thought, scientists report

Financial incentives boost meal replacement therapy success in severely obese adolescents

Exploring non-coding RNAs as regulators of notch signaling in breast cancer

Lario Therapeutics awarded $6M Grant from The Michael J. Fox Foundation for Parkinson’s Research

Beyond the anti-obesity benefits of glucagon-like peptide-1 drugs

New study sheds light on irregular heartbeat risk

Combination of sEphB4-HSA and pembrolizumab shows promise in HPV-negative EphrinB2 positive HNSCC

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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