Clinical Testing News and Research

RSS

Alnylam’s patisiran receives positive opinion from CHMP for treating hATTR amyloidosis

Alnylam Pharmaceuticals, Inc., the leading RNAi therapeutics company, announced today that the Committee for Medicinal Products for Human Use has adopted a Positive Opinion recommending marketing authorization of patisiran for the treatment of hereditary transthyretin-mediated amyloidosis in adults with stage 1 or stage 2 polyneuropathy.

27 Jul 2018

Cutting-edge laboratory technique recapitulates brain development more accurately than ever

A cutting-edge laboratory technique that turns human stem cells into brain-like tissue now recapitulates human brain development more accurately than ever, according to a new study from Case Western Reserve University School of Medicine.

26 Jul 2018

FDA clears shape memory polymer foam for treating vascular complications

Shape Memory Medical recently announced FDA clearance for U.S. marketing of their IMPEDE Embolization Plug, a technology funded by NIBIB and created to block irregular blood vessels.

19 Jul 2018

Virtual reality could offer psychotherapy for fear of heights, study shows

A virtual reality (VR) coach can effectively deliver psychotherapy to help overcome a fear of heights in people with this phobia.

13 Jul 2018

Deadlier subtype of metastatic prostate cancer found to be common than previously thought

A new study of prostate cancer in 202 men, whose cancers had spread and were resistant to standard treatment, found that a surprisingly large number of these cancers – about 17 percent – belong to a deadlier subtype of metastatic prostate cancer.

12 Jul 2018

SUSU scientists develop Russian analog of voice prostheses using 3D printing

People who underwent larynx surgery face a necessity of a voice prosthesis implantation, but such artificial windpipes are only produced abroad.

11 Jul 2018

Researchers investigate how genetic data can be made accessible in medical practice

In a project funded by the Austrian Science Fund FWF, a research group from Vienna investigated how genetic data can be made accessible in medical practice in order to improve the safety and effectiveness of medication.

10 Jul 2018

Only one of 21 genes in BrS genetic test found to be associated with Brugada Syndrome

Clinical laboratories often rely on medical articles and public information on gene disease associations in determining the genes to include on genetic testing panels for specific conditions or the specific results to return to patients.

29 Jun 2018

Unbiased approach reveals how to restore breast cancer drugs’ tumor-killing potential

More than 60 percent of breast cancer cases involve defects in the same biochemical chain of events within cancer cells-- known as the PI3 kinase (PI3K) pathway--but efforts to develop therapies targeting this pathway have met with little success after hundreds of mostly failed clinical trials. And researchers still don't understand why.

26 Jun 2018

Harnessing Pediatric Cancer Genomic Data in the Cloud

Dr. Jinghui Zhang, an esteemed computational biologist at St. Jude Children's Research Hospital discusses her latest study and how technology such as cloud computing is changing the way that scientists carry out research.

21 Jun 2018

New simulation approach predicts efficacy of HIV-prophylaxis medications

A new mathematical simulation approach predicts the efficacy of pre- and post-exposure prophylaxis (PrEP) medications, which help prevent HIV infection. The framework, presented in PLOS Computational Biology by Sulav Duwal and Max von Kleist of Freie Universität Berlin and colleagues, could help streamline development of new PrEP treatments.

18 Jun 2018

EMA grants PRIME designation to Themis' chikungunya vaccine candidate

Themis announced today that the European Medicines Agency has granted PRIority MEdicines designation to its most advanced program in development, a vaccine to prevent chikungunya fever.

11 Jun 2018

Alnylam announces new positive results from Phase 1/2 study of lumasiran in patients with PH1

Alnylam Pharmaceuticals, Inc., the leading RNAi therapeutics company, announced today new positive results from its Phase 1/2 study with lumasiran, an investigational RNAi therapeutic targeting glycolate oxidase for the treatment of Primary Hyperoxaluria Type 1.

8 Jun 2018

Genomic markers can predict lynch syndrome across tumor types

Microsatellite instability and DNA mismatch repair deficiencies can predict Lynch syndrome across tumor types, according to researchers from Memorial Sloan Kettering Cancer Center, who presented this retrospective data analysis in a press conference at the annual meeting of the American Society of Clinical Oncology.

4 Jun 2018

Antimicrobial peptides are promising alternative for combatting antimicrobial resistance

Overuse of antibiotics has led to the spread of multi-resistant bacteria that do not respond to conventional treatments.

29 May 2018

Doctors publish comprehensive proposal to ensure universal access to safe, affordable medications

The skyrocketing cost of prescription drugs is one of the biggest concerns for American voters. However, in his proposal last Friday, President Donald Trump failed to offer any new policies that would expand access, reduce costs, or increase the safety and efficacy of prescriptions.

17 May 2018

Research findings could lead to new therapies to curb ovarian cancer metastasis

In order to spread their destruction, ovarian cancer cells must break free from their tumor home, travel through the fluid in the peritoneal cavity and attach to the outside of the abdominal organs--surfaces that are, by necessity, not sticky.

9 May 2018

American Academy of Sleep Medicine selects 2018 award recipients

Several leaders in the field of sleep medicine and a best-selling author were selected as recipients of the 2018 American Academy of Sleep Medicine awards, which will be presented Monday, June 4, during the plenary session of SLEEP 2018, the 32nd annual meeting of the Associated Professional Sleep Societies, LLC in Baltimore.

27 Apr 2018

Low-cost blood test for multiple myeloma can deliver same diagnostic information as bone biopsy

The diagnosis and treatment of multiple myeloma, a cancer affecting plasma cells, traditionally forces patients to suffer through a painful bone biopsy. During that procedure, doctors insert a bone-biopsy needle through an incision to get a bone marrow sample - or make a larger incision and remove a section of bone via surgery.

20 Apr 2018

Functional connectivity MRI could help detect brain disorders and diseases

There are no laboratory tests to diagnose migraines, depression, bipolar disorder and many other ailments of the brain. Doctors typically gauge such illnesses based on self-reported symptoms and behavior.

18 Apr 2018