Clinical Trial News and Research

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Topical cream activates immune response to suppress skin cancer growth

A topical cream activated the skin's immune defenses and suppressed tumor growth in two preclinical models of cutaneous squamous cell carcinoma (cSCC), one of the most common cancers in the world, according to a study published today in the Journal of Clinical Investigation.

12 Mar 2026

PSMA PET/CT scan may halve unnecessary prostate biopsies

An imaging test could safely halve the number of people who need a biopsy for suspected prostate cancer following inconclusive or reassuring results from an MRI scan, new research has found.

12 Mar 2026

Romiplostim prevents chemotherapy-induced thrombocytopenia in phase 3 trial

Results from a global phase 3 clinical trial led by investigators at Mass General Brigham show that the medication romiplostim can effectively prevent chemotherapy from destroying platelet-producing bone marrow cells, a common complication known as chemotherapy-induced thrombocytopenia.

12 Mar 2026

Structured exercise helps chemotherapy patients maintain cognitive function and mental clarity

New research in the March 2026 issue of JNCCN-Journal of the National Comprehensive Cancer Network suggests that exercise may help people with cancer stay mentally sharp and better able to handle daily tasks, work, and social activities through chemotherapy treatment delivered on an every two-week cycle.

12 Mar 2026

High-dose vitamin D3 does not reduce COVID-19 severity, but may impact long COVID outcomes

In a large, randomized trial, researchers at Mass General Brigham have found that high-dose vitamin D3 did not reduce COVID-19 infection severity, but may impact long COVID outcomes.

12 Mar 2026

Personalized counseling program helps cervical cancer survivors quit smoking

A new study led by UCLA researchers suggests that a personalized counseling program can significantly help women who have survived cervical precancer or cervical cancer to quit smoking - and does so at a cost that researchers say represents good value for healthcare systems.

12 Mar 2026

Prebiotic fiber supplement lowers pain sensitivity in people with knee osteoarthritis

A new study has found that a prebiotic fiber supplement reduced pain, improved grip strength, and lowered pain sensitivity in people with knee osteoarthritis (OA) - with far fewer dropouts than a digital physiotherapy programme.

12 Mar 2026

Hanson Wade - 7th Gene Therapy Analytical Development Summit Europe

Clinical and Regulatory Momentum Puts Gene Therapy Analytics in the Spotlight Ahead of the 7th Gene Therapy Analytical Development Summit.

12 Mar 2026

Apixaban safer than rivaroxaban for treating venous thrombosis

The first clinical trial to compare two commonly used drugs head-to-head for venous thrombosis treatment has found a clear winner: while both drugs work well to prevent recurrent blood clots, apixaban is safer than rivaroxaban, with fewer bleeding complications.

11 Mar 2026

Clinical trial to assess safety, efficacy of new implant for male stress urinary incontinence

Urologists at Vanderbilt Health are enrolling men with stress urinary incontinence (SUI) in a clinical trial named SOPHIA2 to assess the safety and efficacy of the UroActive implant, following an investigational device exemption clearance from the U.S. Food and Drug Administration and the French National Agency for the Safety of Medicines and Health Products.

11 Mar 2026

Blood test marker p-tau217 helps detect early dementia risk in cognitively healthy older women

A long-term study of 2,766 women in the Women’s Health Initiative Memory Study found that higher baseline plasma p-tau217 levels were associated with a greater risk of developing mild cognitive impairment or probable dementia.

11 Mar 2026

Review explores how generative AI could support precision oncology decision-making

A narrative review examines how generative AI tools such as large language models and vision-language models could assist precision oncology by interpreting genomic data, matching patients to clinical trials, and synthesizing complex clinical information. The authors emphasize governance, human oversight, and retrieval-based safeguards to ensure these systems are deployed safely in cancer care.

11 Mar 2026

Viagra ingredient improves symptoms in patients with Leigh syndrome

Sildenafil – an active ingredient also marketed under the name of Viagra – improves symptoms in patients with Leigh syndrome.

11 Mar 2026

Electrical stimulation restores movement and sensory feedback after severe spinal injury

The effects of spinal cord injuries are complex and multifaceted. People lose not only the ability to control the movement of their limbs, but also the ability to receive sensory feedback from them. Both are critical to generate the coordinated movement involved in walking.

11 Mar 2026

DNA origami vaccine platform shows promise against multiple infectious viruses

The COVID-19 pandemic brought messenger RNA (mRNA) vaccines to the forefront of global health care. After their clinical trial stages, the first COVID-19 mRNA vaccine was administered on 8 December 2020 and mathematical models suggest that mRNA vaccines prevented at least 14.4 million deaths from COVID-19 in the first year alone.

11 Mar 2026

A longitudinal guide to early Parkinson’s progression

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Clinical Trial News and Research

Topical cream activates immune response to suppress skin cancer growth

PSMA PET/CT scan may halve unnecessary prostate biopsies

Romiplostim prevents chemotherapy-induced thrombocytopenia in phase 3 trial

Structured exercise helps chemotherapy patients maintain cognitive function and mental clarity

High-dose vitamin D3 does not reduce COVID-19 severity, but may impact long COVID outcomes

Personalized counseling program helps cervical cancer survivors quit smoking

Prebiotic fiber supplement lowers pain sensitivity in people with knee osteoarthritis

Hanson Wade - 7th Gene Therapy Analytical Development Summit Europe

Apixaban safer than rivaroxaban for treating venous thrombosis

Clinical trial to assess safety, efficacy of new implant for male stress urinary incontinence

Blood test marker p-tau217 helps detect early dementia risk in cognitively healthy older women

Review explores how generative AI could support precision oncology decision-making

Viagra ingredient improves symptoms in patients with Leigh syndrome

Electrical stimulation restores movement and sensory feedback after severe spinal injury

DNA origami vaccine platform shows promise against multiple infectious viruses

A longitudinal guide to early Parkinson’s progression

FOXJ1 gene may drive resistance to taxane chemotherapy in advanced prostate cancer

New strategy to fight chronic kidney inflammation

Machine learning model predicts chemical reactions to accelerate drug discovery

Boron neutron capture therapy shows promise for deadly brain tumors

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