Induced Pluripotent Stem Cells News and Research

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Study to examine whether cannabidiol provides therapeutic benefit to children with autism

Researchers at University of California San Diego School of Medicine are preparing a first-of-its-kind, multidisciplinary investigation to determine if and how cannabidiol, a non-psychoactive compound found in the cannabis plant, provides therapeutic benefit to children with severe symptoms of autism spectrum disorder.

27 Apr 2018

Study highlights potential of stem cells derived from adults in regenerative medicine

Donor age does not appear to influence the functionality of stem cells derived from adult body tissues, concludes a new review. The analysis of research on induced pluripotent stem cells (iPSCs) finds that not only are typical signs of aging reversed in iPSCs, but cells derived from both older and younger donors show the same ability to differentiate into mature body cells.

24 Apr 2018

CReM researchers optimize process to engineer disease- or patient-specific lung stem cells

The Center for Regenerative Medicine at Boston University and Boston Medical Center has engineered two new categories of lung epithelial cells in vitro using pluripotent stem cells.

12 Apr 2018

Scientists make important discovery about cellular reprogramming

Researchers have made an important discovery about the cellular reprogramming process used in stem cell research for the development of regenerative medicines.

11 Apr 2018

Researchers create adult-like cardiac model by introducing early stimulation

Researchers are now able to use induced pluripotent stem cells to form a model of human adult-like cardiac muscle by introducing electric and mechanical stimulation at an early stage. Since this muscle is similar to the adult heart, it could serve as a better model for testing the effects of drugs and toxic substances than current tissue engineered heart models.

5 Apr 2018

Discovery of new ALS gene points to cytoskeleton as potential target for drug development

An international team of researchers led by John Landers, PhD, at UMass Medical School, and Bryan Traynor, MD, PhD, at the National Institute on Aging at the National Institutes of Health, has identified KIF5A as a new gene associated with the development of amyotrophic lateral sclerosis.

21 Mar 2018

New 3D tissue model of developing heart could be used to test safety of drugs during pregnancy

The heart is the first organ to develop in the womb and the first cause of concern for many parents.

16 Mar 2018

Researchers create cardiomyocyte molds to mend broken hearts

2.5 billion. That's approximately the number of times the human heart beats in 70 years. And sometimes during the course of its unrelenting contractions and relaxations, the heart muscle can no longer bear the strain.

13 Mar 2018

New technique provides pairs of genetically matched cells to study disease

Researchers led by Dr. Knut Woltjen report a new gene editing method that can modify a single DNA base in the human genome with absolute precision.

6 Mar 2018

New discovery could accelerate clinical translation of stem cell-based therapies

A team of scientists from the University of Colorado School of Medicine and the Charles C. Gates Center for Regenerative Medicine at CU Anschutz has reported a more efficient approach to reprogramming a patient's diseased skin cells into stem cells, raising hopes for future clinical trials and potential cures for critical illnesses.

23 Feb 2018

Researchers describe important step toward gene therapy for patients with Sandhoff disease

Babies with the rare, deadly genetic disorder Sandhoff disease begin to miss developmental milestones just months after birth. Lacking muscle tone, they never learn to sit up, develop heads too large to lift and eventually suffer uncontrollable seizures. There is no cure.

22 Feb 2018

Lab-grown cerebellar cells may help explain how ASD develops at molecular level

Increasing evidence has linked autism spectrum disorder with dysfunction of the brain's cerebellum, but the details have been unclear. In a new study, researchers at Boston Children's Hospital used stem cell technology to create cerebellar cells known as Purkinje cells from patients with tuberous sclerosis complex, a genetic syndrome that often includes ASD-like features.

19 Feb 2018

Stem cell vaccine helps protect mice against numerous cancers, finds study

Lab mice injected with inactivated induced pluripotent stem cells (iPSCs) displayed a significant immune response against lung, breast, and skin cancers. The vaccine also prevented relapses in animals with removed tumors.

16 Feb 2018

Using CRISPR To Produce Induced Pluripotent Stem Cells

An interview with Dr. Sheng Ding about using a modified version of the CRISPR-Cas9 system to produce induced pluripotent stem cells.

9 Feb 2018

Higher susceptibility of some babies to Zika virus has a genetic origin, study shows

Microcephaly, brain calcification, skeletal alterations, auditory and visual deficits - these are examples of the damage that can be caused by Zika virus in babies born to mothers infected during pregnancy.

2 Feb 2018

Role of genetics behind immune disease risk could be missed, scientists suggest

The role of genetics in the risk of having an immune disease could be missed in research, scientists suggest.

29 Jan 2018

Research provides insights into mechanisms governing healthy longevity

Keio University Global Research Institute, Tokyo publishes the January 2018 issue of KGRI Research Frontiers that includes researcher video profiles of Keio University researchers and research highlights from high impact publications including 'Regenerative medicine needs collaboration in and out of science in order to face current and future challenges; ‘Does eating fish protect you from depression?’; ‘Insights into the molecular mechanisms leading to kidney dysfunction in diabetic patients’; and ‘Ageing to 100 and beyond: Insights from demographic, phenotypic and genetic studies.

12 Jan 2018

Induced Pluripotent Stem Cells News and Research

Study to examine whether cannabidiol provides therapeutic benefit to children with autism

Study highlights potential of stem cells derived from adults in regenerative medicine

CReM researchers optimize process to engineer disease- or patient-specific lung stem cells

Scientists make important discovery about cellular reprogramming

Researchers create adult-like cardiac model by introducing early stimulation

Discovery of new ALS gene points to cytoskeleton as potential target for drug development

New 3D tissue model of developing heart could be used to test safety of drugs during pregnancy

Researchers create cardiomyocyte molds to mend broken hearts

New technique provides pairs of genetically matched cells to study disease

New discovery could accelerate clinical translation of stem cell-based therapies

Researchers describe important step toward gene therapy for patients with Sandhoff disease

Lab-grown cerebellar cells may help explain how ASD develops at molecular level

Stem cell vaccine helps protect mice against numerous cancers, finds study

Using CRISPR To Produce Induced Pluripotent Stem Cells

Higher susceptibility of some babies to Zika virus has a genetic origin, study shows

Role of genetics behind immune disease risk could be missed, scientists suggest

Research provides insights into mechanisms governing healthy longevity

UCLA scientists coax human stem cells to become sensory interneurons

Human cardiac-muscle patches improve recovery from heart attack injury

Scientists create artificial human muscles

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