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Charting brain cell epigenomics to reveal origins of psychiatric disorders

In a revealing Genomic Press Interview published today in Genomic Psychiatry, Dr. Maria Margarita Behrens recounts an extraordinary scientific journey that wound through four countries and multiple disciplines before arriving at fundamental questions about how the brain develops and what goes wrong in psychiatric disorders.

6 Jan 2026

Researchers successfully perform coronary artery bypass without cutting the chest wall

In a world-first, a team of researchers at the National Institutes of Health (NIH) and Emory School of Medicine, Atlanta, has successfully performed a coronary artery bypass - a normally open-heart surgery - without cutting the chest wall.

6 Jan 2026

Unveiling genetic links between schizophrenia and osteoporosis

A comprehensive genetic investigation led by Dr. Feng Liu at Tianjin Medical University General Hospital has uncovered striking molecular connections between schizophrenia and bone health, identifying 195 shared genetic loci that may explain why psychiatric patients face elevated fracture risks.

6 Jan 2026

TAAR1 mutation impairs brain signaling in schizophrenia

A genetic mutation passed from mother to children in families affected by schizophrenia has now been shown to completely silence a brain receptor that pharmaceutical companies are racing to target with new drugs.

6 Jan 2026

Why individual differences hold the key to unlocking psychiatric mysteries

In a revealing Genomic Press Interview published today in Genomic Psychiatry, Dr. Noritaka Ichinohe challenges a foundational assumption that has quietly constrained psychiatric research for decades: the belief that meaningful explanation requires averaging away individual differences.

6 Jan 2026

Two isoforms of a cellular energy sensor play distinct, opposing roles in Alzheimer's disease

A comprehensive mini-review published today after peer review in Brain Medicine by Dr. Tao Ma and colleagues at Wake Forest University School of Medicine synthesizes emerging evidence that two isoforms of a critical cellular energy sensor play distinct, and sometimes opposing, roles in Alzheimer's disease.

6 Jan 2026

New exercise-sensing pathway offers hope for osteoporosis treatment

A research team from the Department of Medicine, School of Clinical Medicine, LKS Faculty of Medicine at the University of Hong Kong (HKUMed) has uncovered a key biological mechanism that explains how exercise maintain strong bones, paving the way for novel treatments for osteoporosis and bone loss in people who are unable to engage.

6 Jan 2026

AI method sharply improves noise removal in brain imaging

Obtaining clearer functional MRI data about the brain and its disorders is possible using artificial intelligence, according to Boston College researchers who reported recently in Nature Methods that they developed an AI-assisted method to remove "noise", or image distortions, caused by movement, heartbeat, and other factors.

5 Jan 2026

RSV prevention: A new era for infant protection

Globally, RSV causes millions of respiratory infections each year and is responsible for a large proportion of hospitalizations and deaths among children under five years, with the highest risk concentrated in infants under six months.

5 Jan 2026

Researchers identify hundreds of genes essential for the development of brain cells

An international research team identified hundreds of genes essential for the development of brain cells, including one gene linked to a severe neurodevelopmental disorder not previously described.

5 Jan 2026

First human 'lung-on-chip' model developed using stem cells from a single donor

Researchers at the Francis Crick Institute and AlveoliX have developed the first human 'lung-on-chip' model using stem cells taken from only one person.

2 Jan 2026

Study uncovers how aggressive breast cancer cells escape immune defenses

With a new study in the journal Science Bulletin, researchers at Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University have discovered a new way that aggressive breast cancer cells escape the immune defenses.

1 Jan 2026

Imaging-enhanced knowledge graphs reveal new targets for heart disease treatment

Knowledge graphs are a powerful tool for bringing together information from biological databases and linking what is already known about genes, diseases, treatments, molecular pathways and symptoms in a structured network.

30 Dec 2025

Minimal residual disease monitoring can transform breast cancer care

Despite major therapeutic advances, breast cancer remains prone to recurrence, particularly in patients with early-stage disease who appear disease-free after treatment.

30 Dec 2025

Trial evaluates a traditional Chinese herbal formula for diabetic kidney disease with macroalbuminuria

Diabetic kidney disease affects a growing proportion of people with diabetes and remains the leading cause of end-stage renal disease.

30 Dec 2025

Engineered extracellular vesicles enable antigen-specific regulatory T cell induction

A research team at the Nano Life Science Institute (WPI-NanoLSI) and the Faculty of Medicine at Kanazawa University has developed a new class of engineered extracellular vesicles (EVs) capable of inducing antigen-specific regulatory T cells (Tregs), the immune cells that play a central role in suppressing excessive immune responses.

22 Dec 2025

New CPRIT awards expand cancer prevention and treatment research in South Texas

UT Health San Antonio, the academic health center of The University of Texas at San Antonio (UT San Antonio), received nearly $3 million in new academic and prevention awards as part of the latest funding round announced by the Cancer Prevention Research Institute of Texas (CPRIT).

19 Dec 2025

Viral DNA elements help control early embryonic development

Transposable elements are stretches of DNA that can move around the genome. Many of these DNA sequences originate from long ago, when viruses inserted their genetic material into our ancestors' genomes during infection.

19 Dec 2025

ACE2 protein may play a protective role against high blood pressure and type 2 diabetes

A collaborative study from the MRC Laboratory of Medical Sciences (LMS) and Imperial College London has found that the protein ACE2 may play a protective role against two common conditions, high blood pressure and type-2 diabetes, which affect millions of people worldwide.

19 Dec 2025

Study identifies TAK1 gene as a key brake on cancer immunotherapy

Australian researchers have discovered that the TAK1 gene helps cancer cells survive attack from the immune system, revealing a mechanism that may limit the effectiveness of immunotherapy treatments.

19 Dec 2025