Metabolites News and Research

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How your skin’s microbes shape immunity, inflammation, and chronic skin disease

Skin microbes do more than coexist—they shape immune responses, repair tissue, and influence gene expression across your lifespan. This review explains how disruptions in this microbiome-immune dialogue can lead to eczema, psoriasis, or acne.

2 Apr 2025

What blueberries do and don’t do for your microbiome and heart

Regular blueberry consumption for 12 weeks enriched Coriobacteriales incertae sedis in the gut microbiota of older overweight adults. However, this microbial shift was not linked to significant improvements in cardiometabolic biomarkers.

31 Mar 2025

This molecule links your diet to stroke and Alzheimer’s—here’s how to stop it

A new review explores how TMAO, a gut-derived metabolite from red meat and other foods, contributes to heart and brain diseases. It also highlights promising interventions—like plant-based diets, probiotics, and nutraceuticals—to lower TMAO levels and reduce health risks.

26 Mar 2025

Study shows red wine biomarkers in urine can predict inflammation levels

Researchers found that specific metabolites of resveratrol in urine accurately reflect red wine consumption. These biomarkers were linked to reduced inflammation in older adults at cardiovascular risk, unlike traditional food surveys.

25 Mar 2025

Novel global cooperative phenomena of cell interactions discovered in cervical cancer cells

A Japanese research team has discovered a novel global cooperative phenomena of cell interactions in cervical cancer cells. Their findings suggest that the cells are metabolically connected in a functional network.

25 Mar 2025

Study links kynurenine pathway to adolescent depression

Depression is a mental health condition that affects 280 million people worldwide. It is twice as common in women than men and this pattern starts to develop during adolescence.

25 Mar 2025

What do Blue Zone diets have in common? Polyphenols that may slow aging

Scientists reviewed how polyphenol-rich diets in Blue Zones may help people live longer, healthier lives by targeting biological hallmarks of aging. They call for more research to measure polyphenol intake and test its effects on human longevity.

24 Mar 2025

How your diet and probiotics can improve vaccine effectiveness

Researchers uncover how probiotics and diet shape the gut microbiome to boost vaccine efficacy, offering new avenues for precision immunization.

23 Mar 2025

Duke-NUS and NUS Medicine launch first-ever joint center to drive metabolomics research

In a strategic move for medical research and innovation, Duke-NUS Medical School and the National University of Singapore Yong Loo Lin School of Medicine (NUS Medicine) have launched the Systems Metabolomics Centre (SysMeC), their first-ever joint research center.

22 Mar 2025

Fatty acids in the blood may predict risk of developing schizophrenia from cannabis use

The UPV/EHU study, recently published in the journal Scientific Reports, has analyzed and compared the fatty acids in the blood of individuals with schizophrenia, of those with cannabis use disorder and of those with both diagnoses, with the aim of shedding light on new biomarkers and improving the understanding of the biological relationship between the two disorders.

21 Mar 2025

Exploring the therapeutic potential of flavonoids in type 2 diabetes

Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder with a rapidly increasing global prevalence. It is primarily characterized by insulin resistance, β-cell dysfunction, and impaired glucose homeostasis.

20 Mar 2025

Probiotic drink kefir shows promise in preventing Alzheimer’s

Kefir, a probiotic-rich fermented milk, shows potential in reducing neuroinflammation, oxidative stress, and beta-amyloid buildup, suggesting a role in Alzheimer’s prevention and management. However, more clinical trials are needed to confirm its effectiveness in human patients.

17 Mar 2025

Blood-brain barrier dysfunction and inflammation linked to Down syndrome Regression Disorder

A new research study led by Jonathan D. Santoro, MD, Director of the Neuroimmunology Program at Children's Hospital Los Angeles, shows evidence of dysfunction of the blood-brain barrier and inflammation in the central nervous system in individuals with Down syndrome Regression Disorder (DSRD).

14 Mar 2025

How your gut microbiome shapes anxiety

Researchers examine the role of the gut microbiome in the development of anxiety disorders.

12 Mar 2025

Is red meat good or bad for you? Study explains how amino acids shape the answer

Researchers at Texas Tech University reviewed how red meat proteins and amino acids affect human health, weighing both benefits and risks. Their findings highlight that while red meat provides vital nutrients, overconsumption and poor preparation methods can increase disease risk.

10 Mar 2025

Research links kidney dysfunction to muscle weakness in myotonic dystrophy type 1

Thurman M. Wheeler, MD, of the Department of Neurology at Massachusetts General Hospital, is the senior author of a paper published in Nature Communications, "Analysis of human urinary extracellular vesicles reveals disordered renal metabolism in myotonic dystrophy type 1."

8 Mar 2025

Eating ultra-processed foods harms your gut—here’s how inflammation takes hold

Ultra-processed foods disrupt gut microbiome balance, causing inflammation, reduced microbial diversity, and increased gut permeability. This microbiome imbalance contributes to chronic diseases including diabetes, IBD, cancer, and neurological disorders.

6 Mar 2025

Metabolites News and Research

How your skin’s microbes shape immunity, inflammation, and chronic skin disease

What blueberries do and don’t do for your microbiome and heart

This molecule links your diet to stroke and Alzheimer’s—here’s how to stop it

Study shows red wine biomarkers in urine can predict inflammation levels

Novel global cooperative phenomena of cell interactions discovered in cervical cancer cells

Study links kynurenine pathway to adolescent depression

What do Blue Zone diets have in common? Polyphenols that may slow aging

How your diet and probiotics can improve vaccine effectiveness

Duke-NUS and NUS Medicine launch first-ever joint center to drive metabolomics research

Fatty acids in the blood may predict risk of developing schizophrenia from cannabis use

Exploring the therapeutic potential of flavonoids in type 2 diabetes

Probiotic drink kefir shows promise in preventing Alzheimer’s

Blood-brain barrier dysfunction and inflammation linked to Down syndrome Regression Disorder

How your gut microbiome shapes anxiety

Is red meat good or bad for you? Study explains how amino acids shape the answer

Research links kidney dysfunction to muscle weakness in myotonic dystrophy type 1

Eating ultra-processed foods harms your gut—here’s how inflammation takes hold

Carbs aren’t the hunger culprit: New research overturns belief that glycemic index drives overeating

Daily mango consumption may improve insulin sensitivity in overweight or obese adults

How much plastic are you eating? This new tool finds out

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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