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X-ray tomography reveals the gut-brain connection in Alzheimer's

Scientists led by the Institute of Nanotechnology in Italy, in collaboration with the ESRF, the European Synchrotron in Grenoble, France, have discovered how X-ray micro- and nano- tomography can provide clues on the processes that link the gut neurons with those in the brain and may trigger Alzheimer's.

31 Jan 2025

Gut microbiome may mediate the association between sugary beverages and diabetes

It is well known that consuming sugary drinks increases the risk of diabetes, but the mechanism behind this relationship is unclear.

31 Jan 2025

Researchers develop T cell growth method that enhances cancer-fighting ability in melanoma model

Findings indicate that altering glucose metabolism in T cells boosts their therapeutic potential against melanoma, paving the way for improved immunotherapies.

31 Jan 2025

Hormonal markers could lead to early detection of postpartum depression

Women who go on to develop postpartum depression (PPD) may have characteristic levels of neuroactive steroids, molecules derived from the hormone progesterone, in their blood during the third trimester of pregnancy, according to a new study by researchers at Weill Cornell Medicine and the University of Virginia School of Medicine.

30 Jan 2025

Gut-derived sugars: A potential game-changer for weight management and diabetes

Gut bacteria-produced exopolysaccharides (EPS) help regulate metabolism by modulating gut microbiota, promoting SCFA production, and improving glucose homeostasis. S. salivarius, a key EPS producer, shows potential for obesity and diabetes intervention.

30 Jan 2025

New brain biomarker identifies pain sensitivity and may predict chronic pain risk

A novel biomarker signature combining PAF and CME predicts chronic pain risk, linking brain activity to individual pain sensitivity and treatment strategies.

28 Jan 2025

Cannabis smoke at home linked to secondhand exposure in children

The study links in-home cannabis smoking to elevated THC levels in children, highlighting the need for interventions to reduce secondhand exposure risks.

27 Jan 2025

Dietary intervention restores gut microbiome and offers protection against chronic diseases

Findings indicate that a microbiome restoration diet improves gut health and reduces chronic disease markers, highlighting its cardiometabolic benefits.

27 Jan 2025

Study reveals new mechanism behind gene expression regulation in animal cells

A research team at KAIST has identified the core gene expression networks regulated by key proteins that fundamentally drive phenomena such as cancer development, metastasis, tissue differentiation from stem cells, and neural activation processes.

24 Jan 2025

Study uncovers blood signatures linked to Sudden Infant Death Syndrome

New University of Virginia School of Medicine research revealing the fingerprints of Sudden Infant Death Syndrome within blood samples could open the door to simple tests to identify babies at risk.

22 Jan 2025

Maternal stress in early pregnancy affects long-term health of offspring

Maternal stress hormone levels during early pregnancy can have a lasting effect on the stress system of the offspring.

22 Jan 2025

How gut microbiota impacts childhood obesity

Gut microbiota plays a critical role in childhood obesity by influencing energy metabolism, inflammation, and appetite regulation, with emerging therapeutic strategies like probiotics, dietary interventions, and fecal microbiota transplantation showing promise.

21 Jan 2025

Gut microbes and plant foods: a powerful duo for healthy aging

Gut microbiota and phytochemicals synergize to produce bioactive metabolites that combat aging, reduce inflammation, and enhance healthspan by supporting gut and systemic health.

20 Jan 2025

New research identifies metabolic targets to combat antibiotic-resistant bacterial infections

Targeting unique metabolic pathways in pathogens offers a novel approach to precision antibiotics, addressing the growing challenge of antimicrobial resistance.

17 Jan 2025

A new AI tool for unlocking the secrets of spatial multi-omics in cancer

A new artificial intelligence-powered tool called MISO (Multi-modal Spatial Omics) can detect cell-level characteristics of cancer by looking at data from extremely small pieces of tissue-some as small as 400 square micrometers, equivalent to the width of five human hairs.

16 Jan 2025

Pharmacokinetics of berberine and astragaloside IV in normal and diabetic rats

Announcing a new publication for Acta Materia Medica journal. The UPLC-QqQ-MS/MS method was established, validated, and used for the simultaneous detection of berberine (BBR), astragaloside IV (AST), and the main metabolites to demonstrate the comparative pharmacokinetics of BBR and AST in normal and T2DM rats.

15 Jan 2025