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Research sheds light on Salmonella’s ability to escape gut defenses

A new UC Davis Health study has uncovered how Salmonella bacteria, a major cause of food poisoning, can invade the gut even when protective bacteria are present.

15 Nov 2024

TB pathogen's surprising growth mechanism challenges bacterial biology

The rod-shaped tuberculosis (TB) bacterium, which the World Health Organization has once again ranked as the top infectious disease killer globally, is the first single-celled organism ever observed to maintain a consistent growth rate throughout its life cycle.

15 Nov 2024

Chimeric tagging technique offers new hope in the fight against drug-resistant infections

A new study has developed an innovative approach to combat antibiotic-resistant bacteria by tagging them with a chimeric agent that activates the immune system towards them.

15 Nov 2024

NIH awards $3.96 million to develop combination therapies for superbugs

Gram-negative bacteria pose a serious threat to global health because they can resist multiple antibiotics, making infections difficult to treat, according to the National Institutes of Health.

15 Nov 2024

Maternal RSV vaccination timing optimizes newborn immunity through improved antibody transfer

Maternal RSV vaccination enhances antibody transfer to newborns, with optimal transfer efficiency observed when given at least five weeks before delivery.

14 Nov 2024

Primerdesign launches new animal multiplex assays at London Vet Show

Primerdesign (part of the Novacyt Group), a company focused on the design, manufacture, validation and supply of real-time PCR kits and reagents, announces that it is launching two new assays for gastrointestinal (GI) disease in dogs and cats at the London Vet Show, held from 14-15 November 2024.

From Primerdesign 14 Nov 2024

As California taps pandemic stockpile for bird flu, officials keep close eye on spending

California public health officials are dipping into state and federal stockpiles to equip up to 10,000 farmworkers with masks, gloves, goggles, and other safety gear as the state confirms at least 21 human cases of bird flu as of early November.

14 Nov 2024

Study finds weakness in drug-resistant tuberculosis pathogens

A University of Otago-led study has found highly vulnerable weakness in drug-resistant Mycobacterium tuberculosis, offering a new way to kill them.

13 Nov 2024

Metagenomic sequencing improves detection of rare pathogens in CNS infections

New research shows that metagenomic next-generation sequencing (mNGS) over seven years increased pathogen detection in challenging CNS infections, identifying rare and unexpected microbes often missed by standard testing.

13 Nov 2024

New study links circadian gene variants to winter depression

Variants of the PER3 gene disrupt adrenal adaptation to winter light, leading to serotonin disruption and depression-like behaviors in humanized mice models.

13 Nov 2024

Study provides new insights into the central role of goblet cells

In a recent study, researchers at the University of California, San Diego, have provided new insights into the central role of goblet cells - specialized cells that line the gut - in maintaining a healthy and balanced immune environment within the gastrointestinal (GI) tract.

12 Nov 2024

Next-generation metagenomic sequencing test quickly detects any kind of pathogen

Next-generation metagenomic sequencing test developed at UCSF proves its effectiveness in quickly diagnosing almost any kind of pathogen.

12 Nov 2024

Understanding metabolic alterations and immune dysfunction in acute-on-chronic liver failure

Acute-on-chronic liver failure (ACLF) is a life-threatening condition characterized by acute deterioration of liver function in patients with pre-existing chronic liver disease.

8 Nov 2024

Seasonal influenza adapted and evolved during the COVID-19 pandemic

Although travel restrictions and social measures during the COVID-19 pandemic led to a dramatic global drop in seasonal influenza cases, certain influenza lineages in specific regions kept the virus circulating and evolving, according to a new study.

7 Nov 2024

Hexavalent vaccine can reduce spread of whooping cough

Comprehensive coverage of the hexavalent vaccine can protect against whooping cough and polio, averting disease resurgence, writes Esther Nakkazi.

7 Nov 2024

Berry-flavored vapes impair lung immune response

Alterations in AM function following the exposure to berry-flavored e-cigarettes that lead to poor immune responses to pathogens and reduced host survival.

7 Nov 2024

Deciphering the mechanisms of immune response with probabilistic graphical networks

Over the past two decades, new technologies have helped scientists generate a vast amount of biological data. Large-scale experiments in genomics, transcriptomics, proteomics, and cytometry can produce enormous quantities of data from a given cellular or multicellular system.

5 Nov 2024

WHO study names top pathogens in need of new vaccines

A new World Health Organization (WHO) study published today in eBioMedicine names 17 pathogens that regularly cause diseases in communities as top priorities for new vaccine development.

5 Nov 2024

Exercise temporarily improves muscle insulin resistance linked to genetic risk for type 2 diabetes

The study uncovers how acute exercise alleviates insulin resistance in TBC1D4 variant carriers, underscoring the need for personalized diabetes interventions.

4 Nov 2024

Scientists develop first durable human lip cell models in the lab

We use our lips to talk, eat, drink, and breathe; they signal our emotions, health, and aesthetic beauty. It takes a complex structure to perform so many roles, so lip problems can be hard to repair effectively. Basic research is essential to improving these treatments, but until now, models using lip cells - which perform differently to other skin cells - have not been available.

4 Nov 2024