Transplant News and Research

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CARMAT's Aeson device gains momentum in Europe as a bridge-to-transplant solution

CARMAT (FR0010907956, ALCAR), designer and developer of the world’s most advanced total artificial heart, aiming to provide a therapeutic alternative for people suffering from advanced biventricular heart failure (the “CARMAT”), provides an update on Aeson® artificial heart’s uptake as a bridge to transplant in Europe.

18 Nov 2024

Liver cell aging can trigger multi-organ failure

The aging and failure of cells that occurs when the liver is damaged can spread to other organs, suggests a new study in mice and humans from researchers at UCL, the University of Edinburgh and the CRUK Scotland Institute.

15 Nov 2024

Stem-cell implants restore vision in patients with corneal stem cell deficiency

Researchers successfully tested the safety and preliminary efficacy of stem-cell-derived corneal implants, showing promise for restoring vision in patients with severe corneal damage.

12 Nov 2024

Pandemic stress linked to long-term rise in alcohol consumption

Alcohol use increased during the COVID-19 pandemic and remained elevated even after the pandemic ended, according to a large nationally representative Keck Medicine of USC study published today in the Annals of Internal Medicine.

12 Nov 2024

Research sheds light on how fecal transplants improve gut health

In a novel study that identified male chromosome genetic material in the intestines of female patients undergoing fecal transplants, researchers at Johns Hopkins Medicine say they have significantly expanded scientific understanding of how some of these transplants may succeed and work.

6 Nov 2024

Targeted bacteriophages offer standardized and scalable GI therapy

In a new study, researchers at the University of Copenhagen have been cultivating 'good viruses' from feces. The goal is to replace fecal capsules now being used in so-called fecal transplants. Their new technique has shown potential in studies with mice and the hope is that it will improve this life-saving treatment through standardization and pave its way toward mainstream medicine.

5 Nov 2024

Simple symptom management support improves wellbeing after heart transplant

When a patient with heart failure has received a new heart and survives - the transplantation is deemed a success.

5 Nov 2024

Virtual yoga program shows promise for chronic low back pain relief

Cleveland Clinic researchers found that a 12-week therapeutic virtual yoga program for chronic low back pain can be a feasible, safe and effective treatment option. The findings are published in JAMA Network Open.

1 Nov 2024

Groundbreaking study sheds light on stem cell dynamics post-transplant

For the first time, scientists have tracked what happens to stem cells decades after a transplant, lifting the lid on the procedure that has been a medical mystery for over 50 years.

1 Nov 2024

Innovative injectable filler offers hope for diabetic wound treatment

Researchers at the Terasaki Institute for Biomedical Innovation (TIBI) have developed a revolutionary injectable granular filler that could transform the way diabetic wounds are treated, potentially improving patient outcomes.

1 Nov 2024

AI-powered avatars set for mental health trials in India and Ethiopia

AI-powered digital avatars are to be trialled for people in India and Ethiopia who hear voices in their heads, as researchers try to adapt mental health treatment so they can be used effectively in low-resource settings.

29 Oct 2024

New research unveils mechanism behind deadly neuroendocrine prostate cancer

A leading scientist whose discoveries about prostate cancer led to lifesaving treatments is now shedding light on an emerging and deadlier form of the disease: neuroendocrine prostate cancer (NEPC).

28 Oct 2024

Elucidating the mechanisms behind kidney development

To Alex Hughes, Assistant Professor in Bioengineering within Penn Engineering and in Cell and Developmental Biology within Penn Medicine, the kidney is a work of art. "I find the development of the kidney to be a really beautiful process," says Hughes.

28 Oct 2024

Clinical trial highlights efficacy of imlifidase for kidney transplant recipients

For kidney transplant recipients experiencing antibody-mediated rejection, the current standard of care involves removing donor-specific antibodies (DSAs) through plasmapheresis (PLEX) - a procedure that removes antibodies from the plasma portion of the blood.

27 Oct 2024

Phase 3 trial assesses clazakizumab in kidney transplant recipients with caAMR

Chronic active antibody-mediated rejection (caAMR) is a common cause of allograft loss after transplantation, with no approved therapies. Clazakizumab, a monoclonal antibody that targets the inflammatory cytokine interleukin-6 (IL-6), stabilized kidney transplant recipients' kidney function in a phase 2 trial.

27 Oct 2024

Ipsen's elafibranor recommended for use in patients with rare liver disease

Ipsen announced today that the National Institute for Health and Care Excellence (NICE) has recommended elafibranor 80mg tablets for the treatment of PBC in combination with ursodeoxycholic acid (UDCA) in adults with an inadequate response to UDCA, or as monotherapy in adults unable to tolerate UDCA. This makes elafibranor the first medicine for PBC approved for use on the NHS in nearly a decade.

26 Oct 2024

Advanced fibrosis linked to liver complications in biopsy-proven MASLD

Data regarding risk factors and long-term outcomes of U.S. patients with biopsy-proven metabolic dysfunction-associated steatotic liver disease (MASLD) are limited.

25 Oct 2024

New insights into rejection entities in kidney transplantation

Investigators recently uncovered key insights into newly defined rejection entities in kidney transplantation that may offer improved patient risk categorization post-transplant. The research will be presented at ASN Kidney Week 2024 October 23– 27.

25 Oct 2024

DNA analysis outperforms standard newborn screening, study shows

Early results from a study of newborn screening methods show that DNA analysis picks up many more preventable or treatable serious health conditions than standard newborn screening and is favored by most parents who are offered the option.

24 Oct 2024

myeloMATCH program opens enrollment for acute myeloid leukemia and MDS

Four leading cancer research organizations in the United States and Canada announce the opening of patient enrollment to myeloMATCH, a unique portfolio of clinical trials to test precision medicine treatments for adults with acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS).

23 Oct 2024