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Key plant enzyme could pave way for development of medications and other products

Plants can do many amazing things. Among their talents, they can manufacture compounds that help them repel pests, attract pollinators, cure infections and protect themselves from excess temperatures, drought and other hazards in the environment.

8 Sep 2019

Simple urine analysis can be used to quickly identify brain trauma and expedite treatment

A traumatic brain injury is often easily suspected and can be confirmed and treated if necessary following an injury using a blood analysis, but scientists are reporting that even one mild blast to the brain can cause very subtle but permanent damage as well.

5 Sep 2019

Uncovering how cyanobacteria edit their genomes

Unique editing mechanisms in cyanobacteria, commonly known as blue-green algae, make them able to remove large sections of the genome to give cells the ability to fix nitrogen, when necessary.

7 Aug 2019

Researchers open up possible avenue for new cancer treatments without side effects

Researchers have opened up a possible avenue for new cancer therapies that don't have the side effects that oftentimes accompany many current cancer treatments by identifying a protein modification that specifically supports proliferation and survival of tumor cells.

6 Aug 2019

Research findings could help identify Alzheimer's patients who will benefit from exercise

A novel study has discovered metabolites that predict which Alzheimer's patients are likely to see their symptoms improve with exercise therapy.

6 Aug 2019

Defective immune signals could underlie some types of fatal heart disease

Researchers have come up with exciting evidence that confirms the role of abnormal immune signaling in myocarditis.

25 Jul 2019

Disruption of immune cell behavior may spur heart disease, heart failure

On an ice hockey team, the players all start off with identical uniforms, skates and a stick. But if you take one of them, add padding, a glove, and a mask; and switch the stick to one with a larger blade, then you get a goalie.

From Johns Hopkins Medicine 19 Jul 2019

Gene modulation goes wireless hacking the "boss gene"

Researchers from the University at Buffalo have successfully used technology to wirelessly tweak the functioning of a gene FGFR1. This gene is vital in the growth of embryos into adults. Their experiments were successful in the lab grown brain tissues and shows potential in therapeutics.

16 Jul 2019

Genetic contribution to distractibility helps explain procrastination

Wouldn’t it be nice to blame your genes for your procrastination? Now, using a combination of questionnaires and genetic testing, German researchers have found that with increasing dopamine in the brain, women tended to show greater tendencies to procrastinate.

14 Jul 2019

Researchers determine atomic interactions that stabilize phase-changing proteins

Most of the well-studied proteins in our bodies are like metal; some can change shape easily, like aluminum foil, and others are rigid, like steel beams, but they typically have a solid, well-defined structure.

2 Jul 2019

A metabolic intermediate in the uronic acid pathway impairs lung cancer metastasis

In a study published online in Nature on June 26, research teams led by Dr. YANG Weiwei at the Institute of Biochemistry and Cell Biology of the Chinese Academy of Sciences and Dr. LI Guohui from the Dalian Institute of Chemical Physics of CAS reported a new function of uridine diphosphate glucose (UDP-glucose), a metabolic intermediate in the uronic acid pathway: It impairs lung cancer metastasis by accelerating SNAI1 mRNA decay.

27 Jun 2019

Revolutionary cancer drugs that target any tumor to be fast-tracked into hospitals by NHS

Patients in England could be some of the first in the world to be treated with revolutionary cancer drugs that can target any type of tumor.

19 Jun 2019

Study shows how SIRT1 plays key role in maintaining the regenerative potential of leukemic stem cells

Patients with chronic myeloid leukemia can be treated with tyrosine kinase inhibitors. While these effective drugs lead to deep remission and prolonged survival, primitive leukemia stem cells resist elimination during the remission and persist as a major barrier to cure.

11 Jun 2019

Synthesizing Modified and Pharmaceutically Relevant Peptides

In this interview, CEM Corporation talks to News-Medical Life Sciences about using their product the Liberty Blue for Automated High-Efficiency Solid Phase Peptides Synthesis of Modified and Pharmaceutically Relevant Peptides.

From CEM Corporation - Life Science 24 Apr 2019

Scientists use NIR light and injected DNA nanodevice to guide stem cells to injury

What if doctors had a remote control that they could use to steer a patient's own cells to a wound to speed up the healing process?

18 Apr 2019

New research on psychological and neural basis of Post-Traumatic Stress Disorder

Dr. Stephen Maren, University Distinguished Professor in the Department of Psychological & Brain Sciences, recently published significant research on the psychological and neural basis of Post-Traumatic Stress Disorder.

12 Apr 2019

New targetable vulnerability in breast cancer cells discovered

Researchers at the University of Helsinki and Karolinska Institutet have discovered new molecular mechanisms of breast cancer cell signaling that contribute to aggressive behavior of cancer cells.

29 Mar 2019

Understanding maintenance of quiescent stem cells in chronic myelogenous leukemia

Most patients with chronic myelogenous leukemia can be treated with tyrosine kinase inhibitors. These drugs are highly effective and lead to deep remission and prolonged survival.

22 Mar 2019

New insights into peripartum cardiomyopathy in women

In the current issue of Cardiovascular Innovations and Applications (Special Issue on Women's Cardiovascular Health, Volume 3, Number 4, 2019, Guest Editor Gladys P. Velarde) pp. 403-408(6); DOI: ttps://doi.org/10.15212/CVIA.2017.0066 Dmitry Yaranov, MD and Jeffrey D. Alexis, MD from the College of Medicine, University of Florida, Jacksonville, FL, USA and the University of Rochester, Rochester, NY, USA consider peripartum cardiomyopathy.

2 Mar 2019

New research finds how cancer cells acquire resistance to molecular-targeted drugs

Although molecular-targeted drugs have been known to show high efficacy to lung cancer patients, they also have limitations due to acquiring resistance to the drug used.

25 Feb 2019