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New combined cell therapy for kidney transplants can help reduce donor-specific immune response

A new combined cell therapy for kidney transplants can help to reduce the donor-specific reaction against the transplanted organ without the need for maintenance triple immunosuppression.

22 Jul 2024

Combination therapy incorporating three existing drugs shows potential for treating retinal degenerations

Drug repurposing shows promise in the treatment of retinal degenerations, according to a new study by an international team of researchers, published in Nature Communications.

22 Jul 2024

Study finds limited evidence for massage therapy's effectiveness in pain relief

A study in JAMA Network Open reviews evidence on massage therapy's effectiveness in relieving pain, finding moderate certainty for some conditions but overall low certainty for most.

21 Jul 2024

CD5 knockout using CRISPR boosts CAR T cell therapy efficacy

The effectiveness of CAR T cell therapy against a variety of cancers, including solid tumors, could be boosted greatly by using CRISPR-Cas9 technology to knock out the gene for CD5, a protein found on the surface of T cells, according to a preclinical study from investigators at the University of Pennsylvania's Perelman School of Medicine and Abramson Cancer Center.

19 Jul 2024

Research may pave the way for systemic targeted therapy for patients with pseudomyxoma peritonei

Published in Clinical Cancer Research, results of a preclinical study led by investigators of the Vall d'Hebron Institute of Oncology's (VHIO) Stem Cells and Cancer Group, headed by Héctor G. Palmer, pave the way for systemic targeted therapy in patients with pseudomyxoma peritonei, a rare form of cancer with very few therapeutic options available.

19 Jul 2024

Collaborative grant program boosts health research across Tennessee

Researchers from the University of Tennessee Health Science Center College of Medicine-Knoxville; the University of Tennessee, Knoxville; and the University of Tennessee Health Science Center Office of Research understand the challenges affecting the health and wellness of Tennesseans.

19 Jul 2024

Physical modulation of the tumor microenvironment to enhance cancer therapy

Announcing a new article publication for BIO Integration journal. The tumor microenvironment (TME) has a crucial role in tumor development, metastasis, and recurrence.

19 Jul 2024

Does hormone-modulating therapy for breast cancer treatment affect risk for Alzheimer disease and related dementias?

The association between hormone-modulating therapy (HMT) for breast cancer treatment and the risk of developing Alzheimer's disease and related dementias.

19 Jul 2024

Modulating T-cell response: Innovations in AAV8 gene therapy for retinal diseases

A new study shows that subretinal adeno-associated virus 8 (AAV8) injections cause proinflammatory T-cell immune response against the transgene product.

19 Jul 2024

Deciphering the role of RET in cancer and breakthroughs in targeted treatments

Xueqing Hu , Ujjwol Khatri , Tao Shen , and Jie Wu, at University of Oklahoma Health Sciences Center, USA, provides a comprehensive review of the role of the RET (REarranged during Transfection) receptor tyrosine kinase in cancer development and the advancements in RET-targeted cancer therapies.

19 Jul 2024

Medical debt doubles risk of skipping mental health care for depression and anxiety

Medical debt is significantly more prevalent among adults with depression or anxiety compared to adults without these mental disorders, according to a new study led by researchers at the Johns Hopkins Bloomberg School of Public Health. Among adults with depression or anxiety, those with medical debt were twice as likely to report having delayed or forgone mental health care in the previous 12 months compared to those without medical debt.

19 Jul 2024

Psilocybin reconfigures brain networks, showing potential for lasting therapeutic effects

Researchers found that high-dose psilocybin significantly disrupts brain functional connectivity, particularly in the default mode network, with lasting effects linked to therapeutic benefits.

18 Jul 2024

FDA approval of lifileucel: A milestone in tumor-infiltrating lymphocyte therapy for advanced melanoma

The recent U.S. Food and Drug Administration approval of lifileucel, the first commercial tumor-infiltrating lymphocyte (TIL) therapy for advanced melanoma, marks a significant breakthrough in cancer therapy.

18 Jul 2024

Breakthrough in aging research: Blocking IL-11 extends lifespan and improves health in mice

Blocking IL-11 signaling extends lifespan and healthspan in mice, reducing age-related metabolic decline, frailty, and cancer incidence.

18 Jul 2024

Mobile apps and wearables show promise in easing mental health symptoms during therapy wait times

The recent surge in people seeking mental health care across the country has led to long wait times for first appointments with therapists and psychiatrists.

18 Jul 2024

New drugs show promise in shrinking breast cancer brain metastases

Researchers from Drexel's College of Medicine have identified new drugs that show early success in shrinking breast cancer tumors that have metastasized in the brain.

18 Jul 2024

Ovarian reserve unchanged by hydroxyurea in sickle cell disease, study reveals

In female patients living with sickle cell disease (SCD), hydroxyurea had no effect on ovarian reserve, suggesting that fertility preservation measures prior to treatment may be unnecessary, according to a study published in Blood Advances.

18 Jul 2024

Improving medication adherence beats resistance testing for better HIV outcomes in African youth

Globally, around 2.6 million children and adolescents are currently living with HIV, the majority of them in Africa.

18 Jul 2024

Blocking IL-11 protein extends lifespan and health in mice by 25%, study shows

Scientists at the Medical Research Council Laboratory of Medical Science and Imperial College London have discovered that 'switching off' a protein called IL-11 can significantly increase the healthy lifespan of mice by almost 25%.

18 Jul 2024

Feline gut microbes shed light on obesity treatment for humans

Pet cats may be excellent animal models for the study of obesity origins and treatment in humans, a new study of feline gut microbes suggests – and both species would likely get healthier in the research process, scientists say.

18 Jul 2024

Therapy News and Research

New combined cell therapy for kidney transplants can help reduce donor-specific immune response

Combination therapy incorporating three existing drugs shows potential for treating retinal degenerations

Study finds limited evidence for massage therapy's effectiveness in pain relief

CD5 knockout using CRISPR boosts CAR T cell therapy efficacy

Research may pave the way for systemic targeted therapy for patients with pseudomyxoma peritonei

Collaborative grant program boosts health research across Tennessee

Physical modulation of the tumor microenvironment to enhance cancer therapy

Does hormone-modulating therapy for breast cancer treatment affect risk for Alzheimer disease and related dementias?

Modulating T-cell response: Innovations in AAV8 gene therapy for retinal diseases

Deciphering the role of RET in cancer and breakthroughs in targeted treatments

Medical debt doubles risk of skipping mental health care for depression and anxiety

Psilocybin reconfigures brain networks, showing potential for lasting therapeutic effects

FDA approval of lifileucel: A milestone in tumor-infiltrating lymphocyte therapy for advanced melanoma

Breakthrough in aging research: Blocking IL-11 extends lifespan and improves health in mice

Mobile apps and wearables show promise in easing mental health symptoms during therapy wait times

New drugs show promise in shrinking breast cancer brain metastases

Ovarian reserve unchanged by hydroxyurea in sickle cell disease, study reveals

Improving medication adherence beats resistance testing for better HIV outcomes in African youth

Blocking IL-11 protein extends lifespan and health in mice by 25%, study shows

Feline gut microbes shed light on obesity treatment for humans

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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