Cholesterol News and Research

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Cholesterol is a waxy, fat-like substance made in the liver, and found in the blood and in all cells of the body. Cholesterol is important for good health and is needed for making cell walls, tissues, hormones, vitamin D, and bile acid.

Large numbers of kidney disease patients inappropriately prescribed statins to lower cholesterol

A new analysis concludes that large numbers of patients in advanced stages of kidney disease are inappropriately being prescribed statins to lower their cholesterol - drugs that offer them no benefit and may increase other health risks such as diabetes, dementia or muscle pain.

11 Sep 2013

Binghamton researcher hopes to give docs accurate way of determining patient's risk of heart attack

A Binghamton University researcher hopes to give doctors a more accurate way of determining a patient's risk of heart attack or stroke.

11 Sep 2013

Women veterans at risk for heart disease recruited for mindfulness-based stress reduction study

Loyola University Chicago Marcella Niehoff School of Nursing researchers and Edward Hines, Jr. VA Hospital are recruiting women veterans at risk for heart disease for a mindfulness-based stress reduction study. MBSR is a form of complementary medicine that combines yoga and meditation.

10 Sep 2013

Most patients who report statin intolerance can actually tolerate drugs on subsequent trials

Most patients who report statin intolerance, including muscle aches and other side effects from the cholesterol-lowering drugs, can actually tolerate drugs from this class on subsequent trials, according to research from Cleveland Clinic recently released online and forthcoming in the September issue of the American Heart Journal. The study is the largest ever to examine the effects of re-challenging statin-intolerant patients.

10 Sep 2013

Degeneration of fornix in brain may provide clues to future cognitive decline in healthy old people

The degeneration of a small, wishbone-shaped structure deep inside the brain may provide the earliest clues to future cognitive decline, long before healthy older people exhibit clinical symptoms of memory loss or dementia, a study by researchers with the UC Davis Alzheimer's Disease Center has found.

10 Sep 2013

Short-term blood sugar control in diabetes patients has limited effect on risk of cardiovascular problems

An international study has shown that short-term blood sugar control in patients with diabetes has a limited effect on their risk of cardiovascular problems, such as heart disease and stroke.

6 Sep 2013

Experimental agent fails to increase HDL levels, reveals new study

The search continues for an agent that increases high-density lipoprotein (HDL) and reduces arterial plaque, after the experimental apolipoprotein A1 (apoA1) inducer, RVX-208 failed to do so in the ApoA1 Synthesis Stimulation and Intravascular Ultrasound for Coronary Atheroma Regression Evaluation (ASSURE) study.

5 Sep 2013

Doctor’s recommendations for parents to prevent child’s healthy heart from obesity

Childhood obesity is a national health care crisis. More than one-third of children and teens are overweight or obese. Plus, obese children are more likely to become obese adults.

5 Sep 2013

Golgi apparatus: New target for treatment of acute cerebral infarction

Expression of soluble CD40L has been shown to increase sig-nificantly in conditions such as stroke, myocardial infarction, unstable angina, high cholesterol, or other cardiovascular events. 95% of the circulating CD40L exists in activated platelets.

5 Sep 2013

Case Western researchers establish Kruppel-like factors as master regulators of vascular health

Case Western Reserve researchers have identified a genetic factor that blocks the blood vessel inflammation that can lead to heart attacks, strokes and other potentially life-threatening events.

5 Sep 2013

Underweight women with CAD should gain weight to reduce risk of death

Being underweight increases the death risk of women with coronary artery disease (CAD) by 2-fold, according to research presented at the ESC Congress today by Dr Aziza Azimi from Denmark. The study suggests that underweight women with CAD should gain weight to reduce their risk of death.

5 Sep 2013

People with CVD more likely to take preventive medicines when combined in one pill

People are much more likely to take preventive medicines if they're combined in one pill, an international study has found. The findings are published today in the Journal of the American Medical Association.

5 Sep 2013

RVX-208 drug fails to increase good cholesterol levels in ASSURE trial

Patients with coronary artery disease and low levels of "good cholesterol - or high-density lipoprotein - who were treated with a drug designed to increase HDL levels and reduce coronary plaque build-up, experienced no better results than those treated with placebo, according to research conducted by the Cleveland Clinic Coordinating Center for Clinical Research.

4 Sep 2013

Study: Fixed-dose combination medication helps CVD patients

In a randomized trial that included about 2,000 patients with or at high risk of cardiovascular disease (CVD), use of a fixed-dose combination medication for blood pressure, cholesterol, and platelet control compared to usual care resulted in significantly improved medication adherence after 15 months and small improvements in systolic blood pressure and low-density lipoprotein cholesterol, according to a study in the September 4 issue of JAMA.

4 Sep 2013

Researchers identify mechanisms necessary to live without insulin

Several millions of people around the world suffer from insulin deficiencies. Insulin is a hormone, secreted by the beta cells in the pancreas, which plays a major role in the regulation of energy substrates such as glucose.

4 Sep 2013

More young people show risk factors for common type of strokes

Fifteen percent of the most common type of strokes occur in adolescents and young adults, and more young people are showing risk factors for such strokes, according to a report in the journal Neurology.

4 Sep 2013

Esperion Therapeutics reports positive results from ETC-1002 Phase 2a study for LDL-C treatment

Esperion Therapeutics, Inc., a clinical-stage biopharmaceutical company, today announced positive top-line results from a Phase 2a study of ETC-1002 when added to statin therapy in patients with elevated levels of low density lipoprotein cholesterol (LDL-C or "bad cholesterol").

4 Sep 2013

VolitionRx-led consortium receives grant to develop novel NuQ biomarkers for immune response

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3 Sep 2013

New model to predict which patients are most likely to have severe kidney failure from rhabdomyolysis

Researchers from Brigham and Women's Hospital (BWH) have developed a risk score calculation that can help predict which patients with rhabdomyolysis (a condition that occurs due to muscle damage) may be at risk for the severe complication of kidney failure or death.

3 Sep 2013

New quick test promises to reduce economic, health burden of syphilis cases in Latin America

Demystifying the chemical processes that create a wine's aroma, and the invaluable potential application of that understanding in winemaking, is the new objective of scientists in Uruguay who, with European partners, also recently sequenced the genome of the high-value Tannat grape, from which "the most healthy of red wines" are fermented.

2 Sep 2013

Cholesterol News and Research

Further Reading

Large numbers of kidney disease patients inappropriately prescribed statins to lower cholesterol

Binghamton researcher hopes to give docs accurate way of determining patient's risk of heart attack

Women veterans at risk for heart disease recruited for mindfulness-based stress reduction study

Most patients who report statin intolerance can actually tolerate drugs on subsequent trials

Degeneration of fornix in brain may provide clues to future cognitive decline in healthy old people

Short-term blood sugar control in diabetes patients has limited effect on risk of cardiovascular problems

Experimental agent fails to increase HDL levels, reveals new study

Doctor’s recommendations for parents to prevent child’s healthy heart from obesity

Golgi apparatus: New target for treatment of acute cerebral infarction

Case Western researchers establish Kruppel-like factors as master regulators of vascular health

Underweight women with CAD should gain weight to reduce risk of death

People with CVD more likely to take preventive medicines when combined in one pill

RVX-208 drug fails to increase good cholesterol levels in ASSURE trial

Study: Fixed-dose combination medication helps CVD patients

Researchers identify mechanisms necessary to live without insulin

More young people show risk factors for common type of strokes

Esperion Therapeutics reports positive results from ETC-1002 Phase 2a study for LDL-C treatment

VolitionRx-led consortium receives grant to develop novel NuQ biomarkers for immune response

New model to predict which patients are most likely to have severe kidney failure from rhabdomyolysis

New quick test promises to reduce economic, health burden of syphilis cases in Latin America

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

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Evaluating new approaches for rare disease genomics

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