Infectious Diseases News and Research

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Cooperative research center at LLNL aims to develop vaccines for chlamydia

A cooperative research center that aims to develop vaccines for chlamydia has been established by the National Institutes of Health at Lawrence Livermore National Laboratory.

24 Oct 2019

UAB researchers awarded grant to study a vaccine for gonorrhea

University of Alabama at Birmingham researchers have been awarded a three-year contract with a total potential amount of $10 million to study the efficacy of the vaccine Bexsero - already licensed to prevent meningitis - in protecting vulnerable populations from infection with the bacteria that causes gonorrhea.

23 Oct 2019

SLU research halts toxic protein linked to muscular dystrophy in animal models

There is no cure or treatment for facioscapulohumeral muscular dystrophy, an illness that starts with facial, shoulder and upper arm weakness and eventually affects nearly all skeletal muscles of those with the disease.

23 Oct 2019

Disrupting key immune regulator boosts anti-tumor immunity, enables cancer clearance

The immune system must strike an exquisite balance between vanquishing infections and cancer, while at the same time restraining its activity to avoid inadvertently attacking the body's healthy tissues and organs.

23 Oct 2019

Researchers discover conjugative plasmid that augments virulence in superbug

A recent research led by a scientist at City University of Hong Kong has discovered an easily transmitted DNA piece that can make a new type of hyper-resistant and deadly superbug become hyper-virulent quickly, posing an unprecedented threat to human health.

23 Oct 2019

E. coli superbug spreading by poor toilet hygiene, not through food

A new study published in The Lancet Infectious Diseases on October 22, 2019, says that one common superbug that causes more than 5,000 cases of food poisoning in England every year is spread not through contaminated food but through contaminated toilet surfaces.

23 Oct 2019

New collaboration aims to develop gene-based cures for sickle cell disease and HIV

The National Institutes of Health plans to invest at least $100 million over the next four years toward an audacious goal: develop affordable, gene-based cures for sickle cell disease and HIV.

23 Oct 2019

New $30M contract signed to accelerate TB vaccine development across the country

Tuberculosis (TB) is the number-one cause of death from an infectious disease in the world: In 2017, the most recent data available, 10 million people developed TB and 1.6 million died.

23 Oct 2019

Researchers assess accuracy of lateral flow urine LAM test in detecting TB in HIV-positive people

Tuberculosis (TB) causes more deaths in people living with HIV than any other disease, with more than 300,000 deaths in 2017. When detected, early TB can be treated effectively; however, people with advanced HIV are at high risk of death, often without knowing they have TB.

22 Oct 2019

Researchers receive $3.2 million NIH grant to pursue a deeper understanding of Down syndrome

Mount Sinai researchers have been awarded a $3.2 million grant from the National Institutes of Health to pursue a deeper understanding of Down syndrome, the most common genetic cause of intellectual and developmental disabilities in children and young adults, affecting more than 200,000 individuals in the United States.

22 Oct 2019

Antibiotic resistance doubles in just two decades

Antibiotic resistance poses a grave challenge to many previously curable infectious diseases. At present, antibiotic resistance is proving to increase at a much faster rate compared to the development of new therapies.

21 Oct 2019

Ebola virus vaccine still effective against the infection even in low concentrations

The Ebola virus (EBOV), variant Makona, was the causative agent of the 2014-2016 West African epidemic that took over 11,000 lives and infected nearly 30,000 people. But with the combination of globally-supported containment efforts, health experts were able to track the spread of the outbreak, as well as use precautionary and quarantine procedures.

21 Oct 2019

Neutrophil extracellular traps could cause organ damage in malaria

Malaria is one of the world's deadliest infectious diseases: a small mosquito bite delivers numerous malaria parasites into the bloodstream. The human body defends itself valiantly against the parasite, which usually results in periodic flu-like symptoms and severe fever. Severe cases of the disease are accompanied by tissue damage and result in potentially fatal organ failure.

21 Oct 2019

OPAT adherence device took top prize at IDEA Incubator competition

A device designed to improve adherence to outpatient parenteral antimicrobial therapy took top prize at the second IDEA Incubator, a competition showcasing inventions, products and devices to improve patient care for infectious diseases, which takes place during IDWeek.

18 Oct 2019

Highly diluted candidate Ebola vaccine remains fully protective against disease in macaques

A single dose of a highly diluted VSV-Ebola virus vaccine--approximately one-millionth of what is in the vaccine being used to help control the ongoing Ebola outbreak in the Democratic Republic of the Congo (DRC)--remains fully protective against disease in experimentally infected monkeys, according to National Institutes of Health scientists.

18 Oct 2019

Novel approach brings researchers one step closer to universal flu vaccine

The scourge of the influenza virus devastates health and claims many lives worldwide each year. It is especially daunting because vaccines are only protective when they are well matched to the strains circulating in the population.

18 Oct 2019

Adding plant-based compound to gene therapy could improve treatment outcomes

Gene therapy has broadened the treatment possibilities for those with immune system deficiencies and blood-based conditions, such as sickle cell anemia and leukemia.

17 Oct 2019

Lyme vaccine on the horizon, says new study

Lyme disease is a dreaded disease caused by the bite of an infected tick. The only way to prevent it is by not getting bitten by the tick. However, this is not a practical recommendation, since even today about 300,000 thousand people are diagnosed with this infection, in the US alone, and over 100,000 in Europe, each year.

17 Oct 2019

Common bug repellent may chemically 'cloak' humans from malaria-carrying mosquitos

Since its invention during the Second World War for soldiers stationed in countries where malaria transmission rates were high, researchers have worked to pinpoint precisely how DEET actually affects mosquitos.

17 Oct 2019

Electronic medical record system may improve efforts to prevent antibiotic drug resistance

Adapting features of the electronic medical record system used by doctors in caring for their patients may improve efforts to prevent antibiotic drug resistance, according to Penn State research.

17 Oct 2019

Infectious Diseases News and Research

Cooperative research center at LLNL aims to develop vaccines for chlamydia

UAB researchers awarded grant to study a vaccine for gonorrhea

SLU research halts toxic protein linked to muscular dystrophy in animal models

Disrupting key immune regulator boosts anti-tumor immunity, enables cancer clearance

Researchers discover conjugative plasmid that augments virulence in superbug

E. coli superbug spreading by poor toilet hygiene, not through food

New collaboration aims to develop gene-based cures for sickle cell disease and HIV

New $30M contract signed to accelerate TB vaccine development across the country

Researchers assess accuracy of lateral flow urine LAM test in detecting TB in HIV-positive people

Researchers receive $3.2 million NIH grant to pursue a deeper understanding of Down syndrome

Antibiotic resistance doubles in just two decades

Ebola virus vaccine still effective against the infection even in low concentrations

Neutrophil extracellular traps could cause organ damage in malaria

OPAT adherence device took top prize at IDEA Incubator competition

Highly diluted candidate Ebola vaccine remains fully protective against disease in macaques

Novel approach brings researchers one step closer to universal flu vaccine

Adding plant-based compound to gene therapy could improve treatment outcomes

Lyme vaccine on the horizon, says new study

Common bug repellent may chemically 'cloak' humans from malaria-carrying mosquitos

Electronic medical record system may improve efforts to prevent antibiotic drug resistance

eBook: Advancing infectious disease vaccine development eBook

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