Membrane News and Research

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Manipulating endosomal traffic could be a new target for anti-HIV-1 therapies

HIV-1 replication requires the coordinated movement of the virus's components toward the plasma membrane of an immune cell, where the virions are assembled and ultimately released. A study in The Journal of Cell Biology reveals how a Rab protein that controls intracellular trafficking supports HIV-1 assembly by promoting high levels of an important membrane lipid.

5 May 2015

Scientists grow miniature human myelomas in shell-less chicken eggs to study multiple myeloma

Multiple myeloma is an incurable cancer of the bone marrow. To date, no screening systems have been available to examine the effects of new drugs in a 3D environment. Researchers on the EU project OPTATIO might now fill this gap. They succeeded in growing miniature human myelomas in shell-less chicken eggs in order to screen new marine compounds for anti-myeloma activity.

5 May 2015

Novel Ga-68-PSMA-ligand PET/CT effective for early detection of prostate cancer recurrence

A recent study reported in The Journal of Nuclear Medicine compared use of the novel Ga-68-PSMA-ligand PET/CT with other imaging methods and found that it had substantially higher detection rates of prostate-specific membrane antigen (PSMA) in patients with biochemical recurrence after radical prostatectomy.

5 May 2015

Promising compound blocks production of beta amyloid peptides in Alzheimer's mouse model

Offering a potential early intervention for Alzheimer's disease (AD), researchers at University of California, San Diego School of Medicine and Cenna Biosciences, Inc. have identified compounds that block the production of beta amyloid peptides in mice.

30 Apr 2015

Linkam stages used to study the effects of cryopreservation on the quality of Koala spermatozoa samples

Market leaders in temperature controlled microscopy, Linkam Scientific Instruments report on the use of their temperature controlled stages in the study of the effects of cryopreservation of Koala spermatozoa in Australia.

From Linkam Scientific Instruments 28 Apr 2015

Researchers pinpoint new mechanism responsible for malaria progression

A team of researchers from four universities has pinpointed one of the mechanisms responsible for the progression of malaria, providing a new target for possible treatments.

28 Apr 2015

Common tapeworm drug effectively treats MRSA superbugs in lab

A new study provides evidence from lab experiments that a drug already used in people to fight tapeworms might also prove effective against strains of the superbug MRSA, which kills thousands of people a year in the United States.

24 Apr 2015

UC Davis assistant professor wins Hartwell Foundation award to explore treatment for juvenile diabetes

UC Davis Assistant Professor Mark Huising is a recipient of The Hartwell Foundation 2014 Individual Biomedical Research Award to support his early-stage research toward a cure for juvenile diabetes. Diabetes affects 10 percent of the entire United States population, including approximately a million children. Remarkably, 40 children every day receive the diagnosis of diabetes.

22 Apr 2015

Joseph Roche receives grant to develop improved exercise programs for people with dysferlinopathies

The Wayne State University Eugene Applebaum College of Pharmacy and Health Sciences today announced that Joseph Roche, assistant professor for the physical therapy program in the Department of Health Care Sciences, received a one-year, $100,000 grant from the Jain Foundation for "Developing a Multi-Pronged Strategy for the Clinical Management of Dysferlinopathies," a project that seeks to develop better exercise programs for people with dysferlinopathies, or dysferlin-linked muscular dystrophies.

21 Apr 2015

Vascular cells of vertebrates can fuse with themselves

Cells of the vascular system of vertebrates can fuse with themselves. This process, which occurs when a blood vessel is no longer necessary and pruned, has now been described on the cellular level by Prof. Markus Affolter from the Biozentrum of the University of Basel.

21 Apr 2015

Electronic micropump combined with anticonvulsant drug may treat brain diseases

Many potentially efficient drugs have been created to treat neurological disorders, but they cannot be used in practice. Typically, for a condition such as epilepsy, it is essential to act at exactly the right time and place in the brain.

16 Apr 2015

Autophagy: A new approach to fighting tuberculosis

A new approach to combatting tuberculosis would take advantage of a complex, natural process called autophagy that the human body uses to recycle nutrients, remove damaged cell components, eliminate invading bacteria, and respond to inflammation.

16 Apr 2015

New set of molecules could carry medicines into cells

Just as a scientist dressed in a lab coat and goggles might get stuck behind the velvet rope at a trendy bar, many otherwise good drugs can't get inside cells if they don't look the part. In a report published this week in ACS Central Science, researchers report a new set of molecules that could ferry medicines into cells by taking on the right charge and shape, easily sliding past lipid membranes.

16 Apr 2015

Genetically modified Salmonella can help kill cancer cells

A new study has demonstrated that genetically modified Salmonella can be used to kill cancer cells. The study is published in this week's issue of mBio, an American Society for Microbiology online-only, open access journal.

15 Apr 2015

Haag-Streit Surgical receives FDA 510(k) clearance for intraoperative-OCT camera

HAAG-STREIT SURGICAL announced its intraoperative-OCT camera has received 510(k) clearance from the U.S. Food and Drug Administration for marketing on the largest medical device market in the world.

15 Apr 2015

Women in science: an interview with Professor Dame Carol Robinson, University of Oxford

Professor Dame Carol Robinson has just been announced as the “L’Oréal-UNESCO For Women In Science” European Laureate for 2015...

14 Apr 2015

New automated tool rapidly delivers large particles into mammalian cells

A new device developed by UCLA engineers and doctors eventually help scientists study the development of disease, enable them to capture improved images of the inside of cells and lead to other improvements in medical and biological research.

10 Apr 2015

Researchers identify phenomenon that explains effects of oxidative stress on immune cells

You're up in the mountains, the snow is blindingly white, and the sun is blazing down from the sky: ideal skiing conditions - but any skiers carrying the herpes virus might also have to reckon with the onset of cold sores after their day out.

10 Apr 2015

New biodegradable membrane reduces wound healing time by 50%

Treatments to regenerate skin from burns become tedious and long lasting; however, Mexican researchers developed a biodegradable membrane that allows to transfer skin cells (keratinocytes) to burn wounds, when placed on the wound. The method reduces healing time by 50 percent.

3 Apr 2015

Thomas Jefferson University, Exosome Sciences team up to evaluate new liquid biopsy platform

Today, Thomas Jefferson University announces a partnership with Exosome Sciences Inc. to evaluate a novel liquid biopsy platform that might offer clinicians new and actionable information about a patient's cancer as the disease progresses and changes, via a simple blood test.

3 Apr 2015

Membrane News and Research

Manipulating endosomal traffic could be a new target for anti-HIV-1 therapies

Scientists grow miniature human myelomas in shell-less chicken eggs to study multiple myeloma

Novel Ga-68-PSMA-ligand PET/CT effective for early detection of prostate cancer recurrence

Promising compound blocks production of beta amyloid peptides in Alzheimer's mouse model

Linkam stages used to study the effects of cryopreservation on the quality of Koala spermatozoa samples

Researchers pinpoint new mechanism responsible for malaria progression

Common tapeworm drug effectively treats MRSA superbugs in lab

UC Davis assistant professor wins Hartwell Foundation award to explore treatment for juvenile diabetes

Joseph Roche receives grant to develop improved exercise programs for people with dysferlinopathies

Vascular cells of vertebrates can fuse with themselves

Electronic micropump combined with anticonvulsant drug may treat brain diseases

Autophagy: A new approach to fighting tuberculosis

New set of molecules could carry medicines into cells

Genetically modified Salmonella can help kill cancer cells

Haag-Streit Surgical receives FDA 510(k) clearance for intraoperative-OCT camera

Women in science: an interview with Professor Dame Carol Robinson, University of Oxford

New automated tool rapidly delivers large particles into mammalian cells

Researchers identify phenomenon that explains effects of oxidative stress on immune cells

New biodegradable membrane reduces wound healing time by 50%

Thomas Jefferson University, Exosome Sciences team up to evaluate new liquid biopsy platform

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo