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Biomarker discovery boosts long-COVID prediction accuracy to 78.5%

Researchers identify four critical biomarkers associated with long-COVID, offering a 78.5% accuracy in predicting the condition. This discovery paves the way for diagnostic tests and offers insights into the mechanisms of persistent post-COVID symptoms.

1 Nov 2023

Cancer neuroscience: A new frontier in cancer treatment

Cancer cells hijack normal biological processes, allowing them to multiply. For example, tumors spur construction of new blood vessels, building themselves "highways" to supply nutrients.

1 Nov 2023

Highly sensitive blood test shows promise for early detection of common deadly cancers

Most cancers become deadly by keeping a low profile, causing no symptoms until they're too advanced to treat. Ovarian and gastroesophageal cancers are among the most notorious for this sly disease progression, often leading to late-stage diagnoses.

1 Nov 2023

Augmentation therapy can save lives of people with alpha-1 antitrypsin deficiency, study shows

Boosting levels of a deficient protein has clear survival benefits for people with the genetic condition alpha-1 antitrypsin deficiency (AATD), according to new research led by RCSI University of Medicine and Health Sciences.

1 Nov 2023

New drug shows promise in killing cancer cells with genetic vulnerability

Imagine the body's cells are well-behaved students in the classroom. The "teachers" are tumor suppressor genes, and they make sure cells follow the rules. But when tumor suppressor genes are away, cells may go astray.

1 Nov 2023

New gene editing method creates first mice with human-like COVID-19

Researchers have genetically engineered the first mice that get a human-like form of COVID-19, according to a study published online November 1 in Nature.

1 Nov 2023

Proof-of-concept study holds promise for safer gene therapy techniques for treating immunodeficiencies

Researchers described an approach to edit the recombination-activating gene 2 (RAG2) locus for therapeutic applications.

1 Nov 2023

Does the percentage of slow-wave sleep decline with aging, and are intra-individual declines associated with dementia risk?

Researchers investigated whether slow-wave sleep (SWS) proportions reduced as individuals aged and whether intra-individual decreases were linked to dementia risk.

1 Nov 2023

Hospitalization and mortality risks from COVID-19 by age during SARS-CoV-2 Delta and Omicron variants’ predominance

Age-stratified hospitalization and mortality risks from incident SARS-CoV-2 infections.

1 Nov 2023

Researchers identify key protein biomarkers in MS patients, paving way for personalized treatment strategies

Researchers aimed to identify dependable protein biomarkers for multiple sclerosis (MS).

1 Nov 2023

Advances in grain research illuminate potential for precision nutrition in clinical settings

Grains are a primary source of energy (calories) in the diet.

1 Nov 2023

Positivity about physical activity linked to lower aging anxiety

Since 2011, roughly 10,000 people in the U.S. have turned 65 every day. The Baby Boomer generation and those born before 1946 make up the country's fastest growing age group, which is on track to outnumber children by 2035.

31 Oct 2023

Metabolic increase in the hippocampus is early sign of Alzheimer's disease, study finds

An early phase in the process of developing Alzheimer's disease is a metabolic increase in a part of the brain called the hippocampus, report researchers from Karolinska Institutet in a study published in Molecular Psychiatry.

31 Oct 2023

How one gene shakes up our understanding of male infertility

The study investigates the role of the ACTL7B gene in sperm formation using genetically modified mice and finds that deficiencies in this gene lead to failed spermatogenesis and structural sperm abnormalities. Given the gene's similarity in humans, the findings suggest ACTL7B could serve as a potential biomarker for male infertility.

31 Oct 2023

Speeding up Alzheimer's research: Progerin turbocharges cellular models for quicker drug screening

The study reveals that introducing progerin, a protein associated with accelerated aging, into cellular models of Alzheimer's Disease (AD) can hasten the development of AD-related traits. This innovative approach offers a more efficient method for studying AD mechanisms, potentially accelerating the discovery of new treatments.

31 Oct 2023

New AI tool could lead to precision medicine by predicting drug response

An ideal medicine for one person may prove ineffective or harmful for someone else, and predicting who could benefit from a given drug has been difficult.

31 Oct 2023

AI may help identify potential gonorrhea vaccine proteins

Gonorrhea, a sexually transmitted bacterial infection that affects more than 80 million people worldwide every year, has become resistant to almost all known antibiotics.

31 Oct 2023

New drug gets FDA approval for the treatment of common genetic disease in young boys

A new drug developed by professors from the School of Pharmacy and Pharmaceutical Sciences at Binghamton University has received Food and Drug Administration (FDA) approval for the treatment of patients with Duchenne muscular dystrophy (DMD), a common genetic disease that mostly affects young boys.

31 Oct 2023

Simple dietary substitutions can slash US carbon footprint by over 35%

The environmental and health impact of simple food substitutions in the United States (U.S.) diet.

31 Oct 2023

Unsupervised genome-wide variant effect predictor based on pretraining of DNA language models

The Genomic Pre-trained Network (GPN), a multispecies model developed to learn genome-wide variant effects.

31 Oct 2023

Protein C News and Research

Biomarker discovery boosts long-COVID prediction accuracy to 78.5%

Cancer neuroscience: A new frontier in cancer treatment

Highly sensitive blood test shows promise for early detection of common deadly cancers

Augmentation therapy can save lives of people with alpha-1 antitrypsin deficiency, study shows

New drug shows promise in killing cancer cells with genetic vulnerability

New gene editing method creates first mice with human-like COVID-19

Proof-of-concept study holds promise for safer gene therapy techniques for treating immunodeficiencies

Does the percentage of slow-wave sleep decline with aging, and are intra-individual declines associated with dementia risk?

Hospitalization and mortality risks from COVID-19 by age during SARS-CoV-2 Delta and Omicron variants’ predominance

Researchers identify key protein biomarkers in MS patients, paving way for personalized treatment strategies

Advances in grain research illuminate potential for precision nutrition in clinical settings

Positivity about physical activity linked to lower aging anxiety

Metabolic increase in the hippocampus is early sign of Alzheimer's disease, study finds

How one gene shakes up our understanding of male infertility

Speeding up Alzheimer's research: Progerin turbocharges cellular models for quicker drug screening

New AI tool could lead to precision medicine by predicting drug response

AI may help identify potential gonorrhea vaccine proteins

New drug gets FDA approval for the treatment of common genetic disease in young boys

Simple dietary substitutions can slash US carbon footprint by over 35%

Unsupervised genome-wide variant effect predictor based on pretraining of DNA language models

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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