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Cell therapy slows progression of metachromatic leukodystrophy

In an important discovery, scientists have demonstrated that the progression of a type of genetic brain disease is slowed and symptoms are improved in mice that received cell transplants.

23 Mar 2006

Remicade (infliximab) gains Australian approval for treatment of early rheumatoid arthritis

Schering-Plough Corporation today announced that the Therapeutic Goods Administration of the Department of Health and Ageing in Australia has revised the indication of Remicade (infliximab) to include the treatment of early rheumatoid arthritis (RA) and approved a new indication for psoriatic arthritis (PsA).

23 Mar 2006

Trial of paclitaxel with or without bevacizumab as first-line therapy for locally recurrent or metastatic breast cancer

Results from a large, randomised clinical trial for patients with breast cancer show that those who received bevacizumab (Avastin.) in combination with paclitaxel (Taxol.) survived without the disease getting worse for almost twice as long as patients who received paclitaxel alone.

23 Mar 2006

Researchers combat tuberculosis - help may come from protective protein

Most Americans think of tuberculosis as a disease of the past, but with HIV and drug-resistant strains fueling epidemics in India and Africa, TB kills someone every six seconds across the world.

23 Mar 2006

Raloxifene shows potential benefits in treating prostate cancer

In a study to be published in the April, 2006 issue of the British Journal of Urology International, researchers at Cedars-Sinai Medical Center have shown that Raloxifene, a drug commonly used to treat osteoporosis, has a potential clinical benefit in treating men with prostate cancer.

23 Mar 2006

Low-dose aspirin lowers potential for clot-forming blood cells - in both men and women

In what is believed to be the first direct comparison of blood cell testing in both sexes of 81 milligrams of acetyl salicylic acid a day, Hopkins researchers found aspirin therapy prevents the clumping together of these clot-forming cells, called platelets.

23 Mar 2006

Scientists create new molecule that holds promise in fighting disease via gene therapy

Inherited diseases, as well as many cancers and cardiovascular diseases, may eventually be helped by this approach, which delivers therapeutic genes directly to cells. These genes can correct genetic defects, for example, or help the body's immune system fight cancer cells.

23 Mar 2006

Stem cells, gene therapy and allograft applications show promise for treating orthopaedic conditions

Recent advances in gene therapy, stem cells and other promising applications are offering new hope for patients and helping orthopaedic surgeons provide state-of-the-art treatment for various frame-related conditions.

23 Mar 2006

Jefferson neurosurgeons use innovative "Wingspan Stent System" to open clogged brain arteries

Neurosurgeons at Thomas Jefferson University Hospital in Philadelphia are the first in the region and among the first in the nation to successfully use a new stent specifically designed to open potentially life-threatening clogged arteries in the brain, preventing a stroke.

22 Mar 2006

Breast symmetry can be early indicator of breast cancer

Healthy Women who go on to develop breast cancer tend to have less symmetrical breasts than those women who do not develop the disease, researchers at the University of Liverpool have found.

21 Mar 2006

Study uncovers variations in service on UK's psychiatric wards

A groundbreaking study to assess the state of the nation’s acute psychiatric wards has uncovered substantial variations in service provision and delivery.

21 Mar 2006

Scientists develop new research mice to help understand "good" cholesterol

Scientists at Wake Forest University School of Medicine and colleagues have developed new research mice to help them better understand how the body makes and uses "good" cholesterol to protect against heart attacks and strokes.

21 Mar 2006

Study shows that cell transplantation therapy may improve brain receptor function in patients who suffered from cerebral stroke

Japanese researchers have found a piece of the "missing link" about how bone marrow stromal cells restore lost neurologic function when transplanted into animals exhibiting central nervous system disorders, according to a study in the March issue of the Journal of Nuclear Medicine.

21 Mar 2006

A newly recognized type of immune cell may play an important role in causing asthma

...perhaps explaining why current therapies sometimes fail, report researchers from Children's Hospital Boston in the New England Journal of Medicine.

21 Mar 2006

Facial injections of polylactic acid may help improve loss of fat in the face associated with HIV infection

Facial injections of polylactic acid, a synthetic biodegradable polymer, may help improve the debilitating facial lipoatrophy (loss of fat in the face) associated with HIV infection and its treatment, according to an article in the March issue of Archives of Dermatology.

21 Mar 2006

Inhibiting gamma secretase may prevent amyloid plaque build-up thought to trigger Alzheimer's disease

Oregon Health & Science University is participating in a national study of a drug that may prevent Alzheimer's disease by blocking an enzyme that produces plaques believed to trigger the disorder.

21 Mar 2006

Donepezil (Aricept) helps cognitive function in brain tumor patients after radiation

A drug that is marketed to treat Alzheimer's disease also improves cognitive function, mood and quality of life in brain tumor patients following radiation therapy, according to a research team at Wake Forest University Baptist Medical Center.

21 Mar 2006

Early treatment with pharmacological therapy may reduce hypertension

Patients experiencing high normal blood pressure (HNBP), a precursor to hypertension, may benefit from early treatment with pharmacological therapy, according to new research presented at the American College of Cardiology's 55th Annual Scientific Session.

20 Mar 2006

Atorvastatin could prove an effective therapy for multiple sclerosis

Scientists at the University of California, San Francisco and Stanford University Medical Center are reporting compelling new evidence that the cholesterol-lowering drug atorvastatin could prove an effective therapy for preventing the progression of, and reversing the severity of, multiple sclerosis (MS).

20 Mar 2006

Diabetics benefit less from anti-hypertensive treatment to reduce enlarged heart

Standard blood-pressure-lowering treatment to reduce dangerously enlarged hearts is much less effective and less beneficial in diabetic vs. nondiabetic patients, a team led by NewYork-Presbyterian Hospital/Weill Cornell Medical Center researchers reports in this month's issue of Circulation.

20 Mar 2006

Therapy News and Research

Cell therapy slows progression of metachromatic leukodystrophy

Remicade (infliximab) gains Australian approval for treatment of early rheumatoid arthritis

Trial of paclitaxel with or without bevacizumab as first-line therapy for locally recurrent or metastatic breast cancer

Researchers combat tuberculosis - help may come from protective protein

Raloxifene shows potential benefits in treating prostate cancer

Low-dose aspirin lowers potential for clot-forming blood cells - in both men and women

Scientists create new molecule that holds promise in fighting disease via gene therapy

Stem cells, gene therapy and allograft applications show promise for treating orthopaedic conditions

Jefferson neurosurgeons use innovative "Wingspan Stent System" to open clogged brain arteries

Breast symmetry can be early indicator of breast cancer

Study uncovers variations in service on UK's psychiatric wards

Scientists develop new research mice to help understand "good" cholesterol

Study shows that cell transplantation therapy may improve brain receptor function in patients who suffered from cerebral stroke

A newly recognized type of immune cell may play an important role in causing asthma

Facial injections of polylactic acid may help improve loss of fat in the face associated with HIV infection

Inhibiting gamma secretase may prevent amyloid plaque build-up thought to trigger Alzheimer's disease

Donepezil (Aricept) helps cognitive function in brain tumor patients after radiation

Early treatment with pharmacological therapy may reduce hypertension

Atorvastatin could prove an effective therapy for multiple sclerosis

Diabetics benefit less from anti-hypertensive treatment to reduce enlarged heart

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