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E-cadherin, that cellular touch so important in cancer

E-cadherin is a molecule involved in adhesion between epithelial cells that also seems to have a protective role in cancer, since its loss is associated with tumour progression and metastases formation in a series of different cancers.

16 Oct 2005

New surgical option for breast cancer patients

A new surgical option for breast cancer patients combines removal of the cancerous tumor with breast reduction in one surgical procedure, called oncoplastic surgery, with benefits that include improved cosmetic outcome and reduced risk of complications.

13 Oct 2005

Remicade can improve psoriasis symptoms

An international team led by a dermatologist at The University of Manchester has found that treatment with the emerging drug infliximab, marketed as Remicade, can quickly and significantly improve psoriasis symptoms.

From The University of Manchester 13 Oct 2005

Endocytosis of HIV-1 activates plasmacytoid dendritic cells via toll-like receptor -viral RNA interactions

Progressive disease after HIV infection is inversely correlated with the presence of plasmacytoid dendritic cells (pDCs), a subset of the dendritic cell family and the major producers of type 1 interferon in the body. High numbers of pDCs is related to successful control of HIV.

13 Oct 2005

Discovery of agent that can suppress cancer development

In a case of basic science detective work, researchers at The University of Texas M. D. Anderson Cancer Center have solved the puzzle of the "inconsistent biomarker" and, in the process, may have discovered an agent that can suppress cancer development.

13 Oct 2005

Complementary medicine represents an additional cost to usual care with questionable clinical benefit

The cost-effectiveness of using complementary treatments in the United Kingdom has been the subject of much speculation and controversy.

13 Oct 2005

Canadian adolescents and complementary or alternative medical treatment

While the study does not look at the effectiveness of these treatments, "what's concerning is that young people across the country have different levels of access to alternative therapies as publicly-funded services," says Dr. McColl. "There are noticeable differences in access and utilization based on education, income and geographic location."

13 Oct 2005

No shred of evidence that HIV-positive men who lose fat in their legs reciprocally gain fat in their bellies

There is no syndrome that causes increased belly fat and decreased facial and limb fat among HIV-positive men who take antiretroviral drugs, according to a study by researchers at the San Francisco VA Medical Center and the University of California, San Francisco.

13 Oct 2005

Nanobombs to eradicate cancer

University of Delaware researchers are opening a new front in the war on cancer, bringing to bear new nanotechnologies for cancer detection and treatment and introducing a unique nanobomb that can literally blow up breast cancer tumors.

13 Oct 2005

Innovative therapy lowering body temperature slows down the injury process caused by birth asphyxia

Infants born with oxygen loss who are given an innovative therapy that lowers their entire body temperature by four degrees within the first six hours of life, have a better chance of survival and lower incidence of brain injury

12 Oct 2005

Personalized medicine to improve the outcome for breast cancer patients

As cancer remains a leading cause of death in the United States, early detection and treatment are critical keys to improving the survival rate. Yet, an individual's response to treatment varies considerably, even among cancers of the same histological type.

12 Oct 2005

Severe hypoglycemia - complication of gastric bypass surgery

Physicians monitoring patients who have undergone gastric bypass surgery should be on the alert for a new, potentially dangerous hypoglycemia (low blood glucose) complication that, while rare, may require quick treatment, according to a new study

12 Oct 2005

Novel therapies for pleural mesothelioma

Researchers at New York University School of Medicine and Wayne State University have found a molecule that reveals the early stages of pleural mesothelioma, a chest cancer caused by asbestos. The finding opens the way to a blood test for the disease, according to a new study published in the Oct. 13 issue of The New England Journal of Medicine.

12 Oct 2005

Lowering infant's body temperature within the first six hours of life reduces the chances for disability

Lowering an infant's body temperature to about 92 degrees Fahrenheit within the first six hours of life reduces the chances for disability and death among infants who failed to receive enough oxygen or blood to the brain during birth. The research study findings appear in tomorrow's 2005 New England Journal of Medicine.

12 Oct 2005

New monoclonal antibody that targets immune system B cells shows promise for treating leukemias

In studies with mice, treatment with a new monoclonal antibody that targets immune system B cells has shown considerable promise for treating leukemias, autoimmune diseases and transplant rejection, according to immunologists at Duke University Medical Center.

11 Oct 2005

Very low LDL cholesterol levels appear to be safe for heart patients on statin therapies

"There was no apparent safety concern for patients whose resultant LDL on intensive therapy was lower than current guidelines. There was a trend toward improved clinical outcomes in the lowest LDL groups," said Stephen D. Wiviott, M.D., from Brigham and Women's Hospital in Boston, Massachusetts.

11 Oct 2005

Technique for inserting genes into specific sites on the genome in liver cells

The genes are inserted into non-coding regions of the genome so there is no danger of interfering with the functioning of other genes. Once inserted, the gene remains a permanent part of the cell's genome.

10 Oct 2005

New way to measure the impact of AIDS on the living brain

A new University of California - Los Angeles/University of Pittsburgh imaging study for the first time shows the selective pattern of destruction inflicted by AIDS on brain regions that control motor, language and sensory functions. High-resolution 3-D color scans created from magnetic resonance images (MRI) vividly illustrate the damage.

10 Oct 2005

Performing a sentinel node biopsy prior to mastectomy and reconstruction gives best results

Altering the standard step-by-step procedure that takes women facing a mastectomy from diagnosis to surgery to reconstruction can improve the process and help in determining if immediate reconstruction is the best course of action, according to new research from the University of North Carolina at Chapel Hill.

10 Oct 2005

Fear of falling gait

The patient came into the doctor's office in a wheelchair, weighted down by a diagnosis of Parkinson's disease, taking medication for the disorder and insisting she was unable to stand or walk. Thirty minutes later, after jogging down the hallway, she strolled out the door.

9 Oct 2005

Therapy News and Research

E-cadherin, that cellular touch so important in cancer

New surgical option for breast cancer patients

Remicade can improve psoriasis symptoms

Endocytosis of HIV-1 activates plasmacytoid dendritic cells via toll-like receptor -viral RNA interactions

Discovery of agent that can suppress cancer development

Complementary medicine represents an additional cost to usual care with questionable clinical benefit

Canadian adolescents and complementary or alternative medical treatment

No shred of evidence that HIV-positive men who lose fat in their legs reciprocally gain fat in their bellies

Nanobombs to eradicate cancer

Innovative therapy lowering body temperature slows down the injury process caused by birth asphyxia

Personalized medicine to improve the outcome for breast cancer patients

Severe hypoglycemia - complication of gastric bypass surgery

Novel therapies for pleural mesothelioma

Lowering infant's body temperature within the first six hours of life reduces the chances for disability

New monoclonal antibody that targets immune system B cells shows promise for treating leukemias

Very low LDL cholesterol levels appear to be safe for heart patients on statin therapies

Technique for inserting genes into specific sites on the genome in liver cells

New way to measure the impact of AIDS on the living brain

Performing a sentinel node biopsy prior to mastectomy and reconstruction gives best results

Fear of falling gait

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