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Seroprevalence meta-analysis predicts 643 million already infected by SARS-CoV-2 globally

A recent systematic review and meta-analysis conducted by a team of international scientists reveal low seroprevalence of anti-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies in the general population.

19 Nov 2020

Detectable SARS-CoV-2 antibodies 120 days post-infection in Chicago case study

In a recent study, a team of researchers at Northwestern University, USA, had found that nearly 20 percent seroprevalence in the United States metropolitan site, Chicago, over the summer, during a period when lockdown restrictions were eased. They found that three-quarters of seropositive individuals retained detectable antibodies for at least 120 days or four months.

19 Nov 2020

SARS-CoV-2 immunity can last over six months, study finds

US-based scientists have released a study on preprint server bioRxiv*, titled “Immunological memory to SARS-CoV-2 assessed for greater than six months after infection,” contributing to the enormous research effort currently underway in this area.

19 Nov 2020

UK’s COVID-19 vaccine shows similar safety and immunogenicity results in healthy older adults

The UK's vaccine against SARS-CoV-2 shows similar safety and immunogenicity results in healthy older adults (aged 56 years and over) to those seen in adults aged 18-55 years.

19 Nov 2020

Scientists discover potential strategy to prevent inflammation in COVID-19 patients

The COVID-19 pandemic continues to cause significant illness and death while treatment options remain limited. St. Jude Children's Research Hospital scientists have discovered a potential strategy to prevent life-threatening inflammation, lung damage and organ failure in patients with COVID-19. The research appeared online in the journal Cell.

19 Nov 2020

New understanding of glycan signatures of the SARS-COV-2 S1 spike protein

A team of scientists from the University of Oxford, UK, has revealed that site-specific glycosylation differs between spike proteins derived from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and a viral vector-based vaccine candidate.

18 Nov 2020

"Escape mutations" could help SARS-CoV-2 evade immune attack

Researchers in the United States have identified mutations within severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19) – that can reduce antibody binding to the virus, potentially mediating its escape from immune attack.

18 Nov 2020

COVID-19 during pregnancy can cause placental inflammation and impaired immunity

A new study conducted by a team of researchers at Johns Hopkins University, USA, has observed how pregnant women infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) show stunted antiviral immune responses.

18 Nov 2020

Severe COVID-19 complications linked to gut barrier breakdown

A new study claims that severe COVID-19 is caused by a positive feedback loop triggered by systemic inflammation and mediated by abnormal gut permeability. This finding could potentially help open up new avenues of treatment.

18 Nov 2020

Government-funded scientists laid the groundwork for billion-dollar vaccines

When he started researching a troublesome childhood infection nearly four decades ago, virologist Dr. Barney Graham, then at Vanderbilt University, had no inkling his federally funded work might be key to deliverance from a global pandemic.

18 Nov 2020

Children in Melbourne family developed COVID-19 immune response after exposure to virus

Children in a Melbourne family developed a COVID-19 immune response after chronic exposure to the SARS-CoV-2 virus from their parents, a new case report has found.

18 Nov 2020

Study: e-cigarette users have increased susceptibility to flu, COVID-19

In a controlled study of smokers, nonsmokers, and e-cigarette users, University of North Carolina School of Medicine researchers found that e-cigarette users exhibited significantly altered immune responses to a model of influenza virus infection, suggesting increased susceptibility to disease.

18 Nov 2020

Immunological memory can protect people against new infection after COVID-19 recovery

Until now, it was unclear whether a survived SARS-CoV-2 infection or COVID-19 leads to persistent immunological memory and thus can protect against a new infection.

18 Nov 2020

Fatal chain reaction in Alzheimer's disease starts much earlier than commonly assumed

Alzheimer's disease develops over decades. It begins with a fatal chain reaction in which masses of misfolded beta-amyloid proteins are produced that in the end literally flood the brain.

18 Nov 2020

Bioelectronic rapid test for COVID-19

A recent study presents a bioelectronic sensor platform to detect protein at the single-molecule level that is simple, rapid, and robust enough for widespread POC (point-of-care) or bedside application.

18 Nov 2020

SARS-CoV-2 was circulating in Italy before China recognized its existence

This study, published in the Tumori Journal, sheds light on the possibility that the virus had been spreading in Italy well before the outbreak was officially reported in Wuhan, China.

17 Nov 2020

SARS-CoV-2-specific IgM / IgG responses accurately predict COVID-19 outcome

Researchers from the Huazhong University of Science and Technology and Shanghai Jiao Tong University, China, recently built a proteome microarray with 20 out of the 28 predicted SARS-CoV-2 proteins to help understand IgM/IgG responses specific to SARS-CoV-2.

17 Nov 2020

Males may have higher but more transient SARS-CoV-2 immunity than females post-infection

Adding another piece to the puzzle that is coronavirus disease 2019 (COVID-19) serology, a new study published on the preprint server medRxiv* in November 2020 suggests that males have stronger but more transient anti-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) protective immunity than females.

17 Nov 2020

Widespread COVID-19 testing may be possible with new dried blood tests

Researchers have developed dried blood spot sample testing that could be instrumental in preventing the spread of SARS- CoV-2.

17 Nov 2020

Asymptomatic individuals mount polyfunctional antibody response to SARS-CoV-2

Researchers in France have conducted a study showing that people who are asymptomatic following infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19) – elicit a polyfunctional antibody response to the virus.

16 Nov 2020

Antibodies News and Research

Seroprevalence meta-analysis predicts 643 million already infected by SARS-CoV-2 globally

Detectable SARS-CoV-2 antibodies 120 days post-infection in Chicago case study

SARS-CoV-2 immunity can last over six months, study finds

UK’s COVID-19 vaccine shows similar safety and immunogenicity results in healthy older adults

Scientists discover potential strategy to prevent inflammation in COVID-19 patients

New understanding of glycan signatures of the SARS-COV-2 S1 spike protein

"Escape mutations" could help SARS-CoV-2 evade immune attack

COVID-19 during pregnancy can cause placental inflammation and impaired immunity

Severe COVID-19 complications linked to gut barrier breakdown

Government-funded scientists laid the groundwork for billion-dollar vaccines

Children in Melbourne family developed COVID-19 immune response after exposure to virus

Study: e-cigarette users have increased susceptibility to flu, COVID-19

Immunological memory can protect people against new infection after COVID-19 recovery

Fatal chain reaction in Alzheimer's disease starts much earlier than commonly assumed

Bioelectronic rapid test for COVID-19

SARS-CoV-2 was circulating in Italy before China recognized its existence

SARS-CoV-2-specific IgM / IgG responses accurately predict COVID-19 outcome

Males may have higher but more transient SARS-CoV-2 immunity than females post-infection

Widespread COVID-19 testing may be possible with new dried blood tests

Asymptomatic individuals mount polyfunctional antibody response to SARS-CoV-2

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