Cholesterol News and Research

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Cholesterol is a waxy, fat-like substance made in the liver, and found in the blood and in all cells of the body. Cholesterol is important for good health and is needed for making cell walls, tissues, hormones, vitamin D, and bile acid.

Leisure-time physical activity might reduce risk of SCD among men with low CRF

Dr Laukkanen said: "Sudden cardiac death (SCD) accounts for approximately 50% of deaths from coronary heart disease. SCD typically occurs shortly after the onset of symptoms, leaving little time for effective medical interventions, and most cases occur outside hospital with few or no early warning signs. Finding ways to identify individuals at elevated risk of SCD would allow early interventions on risk factors to be implemented."

2 Sep 2013

Being overweight but metabolically healthy is not linked with increased risk of heart attack

Metabolically healthy women have the same cardiovascular disease risk regardless of their BMI, according to research presented at the ESC Congress today by Dr S-ren Sk-tt Andersen and Dr Michelle Schmiegelow from Denmark.

2 Sep 2013

Effectiveness of community-based rehabilitation programme for cardiovascular prevention

With a growing incidence of cardiovascular disease in Asia, lifestyle modification such as weight loss and routine exercise plays an important role in early primary cardiovascular disease prevention.

2 Sep 2013

Reimbursement systems appear to impact on achievement of cholesterol lowering targets

Dr Gitt said: "There are wide variations between European countries in the achievement of LDL-cholesterol (LDL-C) targets. However the effect of different reimbursement systems on meeting the targets was unknown."

2 Sep 2013

CAD patients with very low LDL-C levels benefit from statin treatment

Dr Nakano said: "Many randomised clinical trials, such as Treating to New Targets (TNT) and PROVE IT-TIMI, have shown that aggressive cholesterol lowering with statins improves clinical outcomes in patients with CAD and high LDL-C levels.1,2 But until now it was not known whether aggressive lipid lowering with statins would also benefit CAD patients with very low LDL-C levels."

2 Sep 2013

Study finds that high potency statins can beat dementia

Dr Lin said: "Statins are widely used in the older population to reduce the risk of cardiovascular disease. But recent reports of statin-associated cognitive impairment have led the US Food and Drug Administration (FDA) to list statin-induced cognitive changes, especially for the older population, in its safety communications."

2 Sep 2013

Deaths from cardiovascular disease higher in winter and lower in summer, says doctor

Dr Marques-Vidal said: "Deaths from cardiovascular disease are higher in winter and lower in summer. We decided to conduct a large scale study to see whether cardiovascular risk factors have a seasonal pattern which could explain the seasonality in deaths."

2 Sep 2013

Life expectancy gap growing between older women in rich and poor countries: Study

Measures taken in developed countries to reduce noncommunicable diseases - the leading causes of death globally - have improved the life expectancy of women aged 50 years and older over the last 20 to 30 years.

2 Sep 2013

Statins offer great potential as anti-aging therapy

Not only do statins extend lives by lowering cholesterol levels and reducing the risks of cardiovascular disease, but new research in the September 2013 issue of The FASEB Journal suggests that they may extend lifespans as well. Specifically, statins may reduce the rate at which telomeres shorten, a key factor in the natural aging process. This opens the door for using statins, or derivatives of statins, as an anti-aging therapy.

30 Aug 2013

Dezima starts DEZ-001 Phase 2b study in patients with mild dyslipidemia

Dezima Pharma, the biotechnology company developing innovative drugs in the field of dyslipidemia, announced today the initiation of a double blind, placebo controlled, Phase 2b dose ranging study of DEZ-001 (previously TA-8995), alone and in combination with statins, in order to study the effects on a wide range of lipids and other biomarkers of cardiovascular disease in patients with mild dyslipidemia.

30 Aug 2013

Study to test ability of doxycycline dose to reduce growth of abdominal aortic aneurysms

A new clinical study at the University of Michigan Health System will test the ability of a once daily dose of doxycycline to reduce the growth of small abdominal aortic aneurysms.

29 Aug 2013

Study suggests evaluations of ACO programs may need to consider patient utilization of clinical, economic benefits

Payment incentives implemented with a commercial accountable care organization (ACO) initiative in Massachusetts -Blue Cross Blue Shield's Alternative Quality Contract (AQC) - were associated with lower spending for Medicare enrollees served by the provider groups participating in the AQC, findings that suggest that evaluations of ACO programs may need to consider the implications for other patient populations to assess their full clinical and economic benefits, according to a study in the August 28 issue of JAMA.

29 Aug 2013

Loyola's success in implementing standard of care for heart attack patients recognized by AHA

Loyola University Medical Center has received the American Heart Association's Mission: Lifeline Silver Receiving Quality Achievement Award, which recognizes Loyola's commitment and success in implementing an exceptional standard of care for heart attack patients.

29 Aug 2013

Inflammatory status upregulated in first-episode schizophrenia

Patients with first-episode schizophrenia exhibit upregulation of key proinflammatory molecules, study findings show.

28 Aug 2013

Clinical trial to study benefits of statins in prevention of heart attacks and strokes

Charles H. Hennekens, M.D., Dr.P.H., the first Sir Richard Doll Professor and senior academic advisor to the dean in the Charles E. Schmidt College of Medicine at Florida Atlantic University, recently published a commentary in the American Journal of Medicine, about the benefits of statins in the prevention of heart attacks and strokes in subjects previously thought at too low a risk to be treated.

28 Aug 2013

Vanderbilt adds genetic screening for drug tacrolimus to PREDICT program

Vanderbilt has added genetic screening for the drug tacrolimus to its personalize medicine pharmacogenomics program PREDICT. The new drug screening protocol was added following data that shows a single genetic variation largely impacts different dose requirements for patients.

27 Aug 2013

Mount Sinai scientists receive NIH grant to study clinical benefit of IGF-1 in children with PMS

Scientists at the Seaver Autism Center at the Icahn School of Medicine at Mount Sinai have received a grant from the National Institutes of Health to study Insulin-Like Growth Factor-1, a promising treatment for a subtype of autism called Phelan McDermid Syndrome.

27 Aug 2013

Unique computer technology opens up discovery of smarter drugs to treat illnesses

A unique computer technology that opens up the discovery of smarter drugs to treat major illnesses including heart disease has been invented by University of Strathclyde scientists.

27 Aug 2013

Bioactive compounds in coffee may prevent prostate cancer recurrence, delay progression

Coffee consumption is associated with a lower risk of prostate cancer recurrence and progression, according to a new study by Fred Hutchinson Cancer Research Center scientists that is online ahead of print in Cancer Causes & Control.

27 Aug 2013

Scientists receive NIH grant to study commercially-available drug for treatment of PMS

Scientists at the Seaver Autism Center at the Icahn School of Medicine at Mount Sinai have received a grant from the National Institutes of Health (NIH) to study Insulin-Like Growth Factor-1 (IGF-1), a promising treatment for a subtype of autism called Phelan McDermid Syndrome (PMS).

26 Aug 2013

Cholesterol News and Research

Further Reading

Leisure-time physical activity might reduce risk of SCD among men with low CRF

Being overweight but metabolically healthy is not linked with increased risk of heart attack

Effectiveness of community-based rehabilitation programme for cardiovascular prevention

Reimbursement systems appear to impact on achievement of cholesterol lowering targets

CAD patients with very low LDL-C levels benefit from statin treatment

Study finds that high potency statins can beat dementia

Deaths from cardiovascular disease higher in winter and lower in summer, says doctor

Life expectancy gap growing between older women in rich and poor countries: Study

Statins offer great potential as anti-aging therapy

Dezima starts DEZ-001 Phase 2b study in patients with mild dyslipidemia

Study to test ability of doxycycline dose to reduce growth of abdominal aortic aneurysms

Study suggests evaluations of ACO programs may need to consider patient utilization of clinical, economic benefits

Loyola's success in implementing standard of care for heart attack patients recognized by AHA

Inflammatory status upregulated in first-episode schizophrenia

Clinical trial to study benefits of statins in prevention of heart attacks and strokes

Vanderbilt adds genetic screening for drug tacrolimus to PREDICT program

Mount Sinai scientists receive NIH grant to study clinical benefit of IGF-1 in children with PMS

Unique computer technology opens up discovery of smarter drugs to treat illnesses

Bioactive compounds in coffee may prevent prostate cancer recurrence, delay progression

Scientists receive NIH grant to study commercially-available drug for treatment of PMS

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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