Laboratory News and Research

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Alternative splicing in neurodegenerative disease and the promise of RNA-based therapeutic strategies

Alternative splicing, a clever way a cell generates many different variations of messenger RNAs - single-stranded RNAs involved in protein synthesis - and proteins from the same stretch of DNA, plays an important role in molecular biology.

21 Jun 2023

Newborn screening facilitates early identification of infants with severe combined immunodeficiency

Introducing widespread screening of newborns for a deadly disease called severe combined immunodeficiency, or SCID, followed by early treatment boosted the five-year survival rate of children with the disorder from 73% before the advent of screening to 87% since, researchers report.

20 Jun 2023

Research explains mechanisms behind anti-viral protection in hemochorial placentas

Give credit to your dad's gene for keeping you safe during those long months in your mother's womb.

20 Jun 2023

Study shows therapeutic potential of HK for treating degenerative rotator cuff injury in humans

The incidence of degenerative rotator cuff injury in the elderly poses a significant economic burden. A novel study by investigators in The American Journal of Pathology, published by Elsevier, has established that mitochondrial sirtuin 3 (SIRT3) activator honokiol (HK) promotes healing of rotator cuff injury in aged mice.

20 Jun 2023

H.E.L Group expands into new purpose-designed facilities

Bespoke lab and office space designed to foster innovation and collaboration with colleagues and customers.

From H.E.L Group 20 Jun 2023

EPFL researchers achieve near-perfect control of individual molecules for improving sensing precision

Aleksandra Radenovic, head of the Laboratory of Nanoscale Biology in the School of Engineering, has worked for years to improve nanopore technology, which involves passing a molecule like DNA through a tiny pore in a membrane to measure an ionic current.

19 Jun 2023

Molecular cargo released by cancer cells lays the groundwork for leukemia spread

Tiny packets of molecular cargo shed by cancer cells seed the foundations for metastasis at distant sites in the body.

19 Jun 2023

Oral probiotic bacterial strain found to improve dry eye disease in animal model

In a study by a research group at Baylor College of Medicine, oral administration of a commercially available probiotic bacterial strain was found to improve dry eye disease in an animal model.

18 Jun 2023

Intravenous treatment with MK-3402 can be an effective strategy in fighting antimicrobial resistance

New research by investigators in Ghent, Belgium shows that intravenous treatment with MK-3402, a metallo-beta-lactamase inhibitor, can be an effective strategy in fighting antimicrobial resistance. The findings are presented at ASM Microbe 2023, the annual meeting of the American Society for Microbiology.

18 Jun 2023

Researchers find an upsurge in antimicrobial-resistant C. auris infections

Candida auris, an emerging fungal pathogen resistant to many antimicrobial agents, continues to threaten U.S. public health.

18 Jun 2023

Commercially available tests to identify Candida auris susceptibility perform poorly

Matching an infection with Candida auris, a pathogenic yeast, to an effective antifungal is a critical clinical decision.

18 Jun 2023

Researchers identify several steps in a cellular process responsible for triggering inflammatory responses

Cedars-Sinai investigators have identified several steps in a cellular process responsible for triggering one of the body's important inflammatory responses.

16 Jun 2023

Disorientating the malaria parasite to prevent its replication and transmission

With almost 250 million cases a year, 621,000 of them fatal, malaria remains a major public health problem, particularly in sub-Saharan Africa.

16 Jun 2023

MGI partners with Xpress Genomics to advance deep single-cell RNA-sequencing technologies

MGI, a company committed to building core tools and technology to lead life science, announced the signing of a licensing agreement with Xpress Genomics, a leading Stockholm-based company specializing in automated and scalable RNA-sequencing strategies.

From MGI 16 Jun 2023

MGI and AddLife AB announce strategic collaboration for expanded distribution of MGI products* in the Nordic Region

MGI Tech Co. Ltd. ("MGI"), a company committed to building core tools and technology to lead life science, are delighted to announce a comprehensive collaboration with AddLife AB, one of Europe's largest distributors of clinical testing and laboratory equipment, headquartered in Stockholm.

From MGI 16 Jun 2023

Study concludes a single intramuscular injection of adintrevimab provides prophylactic efficacy against COVID-19 without safety concerns

Researchers evaluated the prophylactic immune protection conferred by a single intramuscular injection of adintrevimab (ADG20) against symptomatic COVID-19.

16 Jun 2023

Determining the effect of estriol treatment on cerebral cortex in the preclinical model of MS

Treating a mouse model of multiple sclerosis with the pregnancy hormone estriol reversed the breakdown of myelin in the brain's cortex, a key region affected in multiple sclerosis, according to a new UCLA Health study.

16 Jun 2023

Aging impacts cellular composition across the whole fly: Study

As the body ages, organ function progressively declines and the risk for a wide range of diseases, including cardiovascular disease, cancer and neurodegenerative diseases, increases. Understanding how the body ages is an intense area of research as it will potentially illuminate ways to promote healthy aging.

16 Jun 2023

Generative AI could serve as a promising tool to assist medical professionals

In a recent experiment published in JAMA, physician-researchers at Beth Israel Deaconess Medical Center (BIDMC) tested one well-known publicly available chatbot's ability to make accurate diagnoses in challenging medical cases.

16 Jun 2023

$New facile strategy for proteome analysis using ultracentrifugation fractionation$

New facile strategy for proteome analysis using ultracentrifugation fractionation

Urine is one of the attractive sources for early and sensitive biomarker discovery since it can accumulate and reflect changes in the human body while being collected non-invasively.

16 Jun 2023

Laboratory News and Research

Alternative splicing in neurodegenerative disease and the promise of RNA-based therapeutic strategies

Newborn screening facilitates early identification of infants with severe combined immunodeficiency

Research explains mechanisms behind anti-viral protection in hemochorial placentas

Study shows therapeutic potential of HK for treating degenerative rotator cuff injury in humans

H.E.L Group expands into new purpose-designed facilities

EPFL researchers achieve near-perfect control of individual molecules for improving sensing precision

Molecular cargo released by cancer cells lays the groundwork for leukemia spread

Oral probiotic bacterial strain found to improve dry eye disease in animal model

Intravenous treatment with MK-3402 can be an effective strategy in fighting antimicrobial resistance

Researchers find an upsurge in antimicrobial-resistant C. auris infections

Commercially available tests to identify Candida auris susceptibility perform poorly

Researchers identify several steps in a cellular process responsible for triggering inflammatory responses

Disorientating the malaria parasite to prevent its replication and transmission

MGI partners with Xpress Genomics to advance deep single-cell RNA-sequencing technologies

MGI and AddLife AB announce strategic collaboration for expanded distribution of MGI products* in the Nordic Region

Study concludes a single intramuscular injection of adintrevimab provides prophylactic efficacy against COVID-19 without safety concerns

Determining the effect of estriol treatment on cerebral cortex in the preclinical model of MS

Aging impacts cellular composition across the whole fly: Study

Generative AI could serve as a promising tool to assist medical professionals

New facile strategy for proteome analysis using ultracentrifugation fractionation

A guide to density measurement excellence eBook

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Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo