immunity News and Research

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SARS-CoV-2 B.1.1.420 and B.1.617.1 immune escape variants reported in France

Researchers discovered the first N440K variant and the new E484Q and L452R Indian variants isolated in France in a recent study. They presented the genetic mutations in the isolated genomes and the phylogenetic tree, including these strains among different SARS-CoV-2 clades. This work is posted on the bioRxiv preprint server.

18 May 2021

Western diet impairs the gut immune system, could increase risk of inflammatory bowel disease

Eating a Western diet impairs the immune system in the gut in ways that could increase risk of infection and inflammatory bowel disease, according to a study from researchers at Washington University School of Medicine in St. Louis and Cleveland Clinic.

18 May 2021

Researchers identify specific influenza targets that could lead to universal flu vaccine for indigenous populations

Researchers have identified specific influenza targets that could be used to better protect Indigenous people from experiencing severe influenza disease through a universal, T cell-based vaccine.

18 May 2021

SpaceX study profiles evolution of antibody response during COVID-19 infection

New research published on the preprint server bioRxiv* suggests S2-specific antibody responses are critical in recovering from mild to severe COVID-19 infection. Compared to patients who died within 28 days of their COVID-19 diagnosis, patients who produced a wide range of S2-specific responses were more likely to survive.

18 May 2021

Around half of U.S. parents unwilling to vaccinate their children against COVID-19

A national online survey in March 2021 found only 49.4% of parents living in the United States were planning to vaccinate their child. A parents’ vaccination status and level of vaccine hesitancy were associated with adolescent vaccinations against COVID-19.

18 May 2021

Milder COVID-19 in children may be due to higher memory B cells responses to SARS-CoV-2

A new research paper published in the journal Science explores the differences in coronavirus-specific B memory cell repertoires in children versus adults, as well as the functional importance of this discovery.

18 May 2021

COVID-19 mRNA vaccines safe and effective for pregnant and breastfeeding women

The current coronavirus disease 2019 (COVID-19) pandemic has brought untold devastation in its wake, with its rapid and asymptomatic spread to hundreds of millions of people the world over. Vaccines have been hailed as the way out of this situation, and a dozen or so are being rolled out in many different countries.

18 May 2021

Breastfeeding safe and beneficial in SARS-CoV-2 infection

\With the onset of the coronavirus disease 2019 (COVID-19) pandemic, hundreds of millions of people became infected worldwide, including thousands of pregnant women near term. The question of vertical transmission to the infant via the placenta or breast milk was very real, leading to a near-total ban on breastfeeding in this group.

17 May 2021

Study provides valuable insight for preventing global pandemics

Whether it's plankton exposed to parasites or people exposed to pathogens, a host's initial immune response plays an integral role in determining whether infection occurs and to what degree it spreads within a population, new University of Colorado Boulder research suggests.

17 May 2021

Delaying second dose of covid-19 vaccine could result in lower mortality under certain conditions

Delaying the second dose of covid-19 vaccines, at least for people aged under 65, could result in up to 20% lower mortality, but only under certain conditions, finds a US study published by The BMJ today.

17 May 2021

A leading group of scientists working in universities, research centres, and innovative companies across Belgium, Germany, Greece, Portugal, Spain, and Switzerland just initiated a groundbreaking project hoping to treat stroke once and for all. The project, given the code name “ANGIE”, is backed by EU funding. "European scientists started developin

17 May 2021

A SARS-CoV-2 neutralizing antibody with extensive spike binding coverage

In a recently published research paper in the journal Nature Communications, a team of scientists from China has described the antiviral efficacy of a novel anti-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibody isolated from recovered coronavirus disease 2019 (COVID-19) patients.

17 May 2021

Antibody to SARS-CoV-2 inhibits complement hyperactivation

Although several monoclonal antibodies against the SARS-CoV-2 spike protein have been developed and clinically tested, little is known about antibodies to the nucleocapsid protein. In a paper published recently in the journal Nature Communications, researchers report a human monoclonal antibody that targets the nucleocapsid protein.

17 May 2021

Moderna and Pfizer-BioNTech vaccines induce robust T cell response against SARS-CoV-2 variants

Researchers in the United States have conducted a study showing the efficacy of the Moderna and Pfizer-BioNTech vaccines at eliciting a robust T cell response against variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

16 May 2021

Enhanced version of CureVac’s COVID-19 vaccine could help address supply shortages

Researchers in Germany have demonstrated the preclinical effectiveness of a next-generation coronavirus disease 2019 (COVID-19) vaccine at enhancing antibody responses against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

16 May 2021

What does approval of the Pfizer vaccine for teens and preteens mean for my child?

Extending the emergency use of the Pfizer-BioNTech vaccine to preteens and young adolescents adds nearly 17 million more Americans to the pool of those eligible to be immunized against covid-19, helping to build a vaccinated population closer to herd immunity. Moderna and Johnson & Johnson are also testing the efficacy of their vaccines in teens and children.

14 May 2021

UCL scientists identify new immunotherapy to combat hepatitis B virus

Scientists at UCL have identified a new immunotherapy to combat the hepatitis B virus (HBV), the most common cause of liver cancer in the world.

14 May 2021

A look at how coronavirus disease (COVID-19) affects Parkinson's

Earlier, herpes simplex virus (HSV), influenza virus A, measles virus, cytomegalovirus (CMV), and mumps virus have all been associated with after-effects of the virus that includes Parkinson's disease (PD). This list may now include SARS-CoV-2.

14 May 2021

A SARS-CoV-2 ferritin nanoparticle vaccine elicits broad immunity

In a recent bioRxiv* preprint research paper, M. Gordon Joyce et al. designed engineered nanoparticle immunogens that recapitulate the structural and antigenic properties of prefusion Spike (S), S1 and receptor-binding domain (RBD). They demonstrated that these immunogens induced robust S-binding, ACE2 (angiotensin-converting enzyme)-inhibition, and authentic and pseudovirus neutralizing antibodies against SARS-CoV-2 in mice.

13 May 2021

Dominance of South African SARS-CoV-2 variant in the US is unlikely but possible

Researchers in the United States and Canada have conducted a study showing that the South African variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19) – is unlikely to become the dominant strain in the US.

13 May 2021

immunity News and Research

SARS-CoV-2 B.1.1.420 and B.1.617.1 immune escape variants reported in France

Western diet impairs the gut immune system, could increase risk of inflammatory bowel disease

Researchers identify specific influenza targets that could lead to universal flu vaccine for indigenous populations

SpaceX study profiles evolution of antibody response during COVID-19 infection

Around half of U.S. parents unwilling to vaccinate their children against COVID-19

Milder COVID-19 in children may be due to higher memory B cells responses to SARS-CoV-2

COVID-19 mRNA vaccines safe and effective for pregnant and breastfeeding women

Breastfeeding safe and beneficial in SARS-CoV-2 infection

Study provides valuable insight for preventing global pandemics

Delaying second dose of covid-19 vaccine could result in lower mortality under certain conditions

A SARS-CoV-2 neutralizing antibody with extensive spike binding coverage

Antibody to SARS-CoV-2 inhibits complement hyperactivation

Moderna and Pfizer-BioNTech vaccines induce robust T cell response against SARS-CoV-2 variants

Enhanced version of CureVac’s COVID-19 vaccine could help address supply shortages

What does approval of the Pfizer vaccine for teens and preteens mean for my child?

UCL scientists identify new immunotherapy to combat hepatitis B virus

A look at how coronavirus disease (COVID-19) affects Parkinson's

A SARS-CoV-2 ferritin nanoparticle vaccine elicits broad immunity

Dominance of South African SARS-CoV-2 variant in the US is unlikely but possible

Exploring Strategies for Targeting Kinases in Innate Immunity eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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