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Enhancing adoptive T-cell therapy with nanowire innovation

Adoptive T-cell therapy has revolutionized medicine. A patient's T-cells - a type of white blood cell that is part of the body's immune system - are extracted and modified in a lab and then infused back into the body, to seek and destroy infection, or cancer cells.

24 Jun 2024

New study in rhesus macaques offers early intervention window for Alzheimer's

Research in nonhuman primates is opening the possibility of testing treatments for the early stages of Alzheimer's and similar diseases, before extensive brain cell death and dementia set in.

24 Jun 2024

Primitive endoderm in early embryos may be key to creating new effective fertility treatments

An unexpectedly versatile and regenerative stem cell in early embryos may be key to creating new effective fertility treatments, suggests a new study in mice from the University of Copenhagen.

24 Jun 2024

Study reveals early immune responses to SARS-CoV-2, offering insights for future COVID-19 treatments

Researchers analyzed early immune responses to SARS-CoV-2 using single-cell multi-omics, revealing key cellular states associated with different infection outcomes.

24 Jun 2024

Bridging knowledge and confidence to increase skin self-examinations

It's summer and time to enjoy the sunshine. But it's also important to do so safely. Skin cancer is the most common form of cancer in the United States - and it's most commonly caused by sun exposure.

24 Jun 2024

Study sheds light on the role of signaling pathway in the brain to prevent neuroinflammation

A new study led by University of Cincinnati researchers sheds new light on the role of a signaling pathway in the brain to maintain health and prevent inflammation and cognitive deficits.

24 Jun 2024

DiffPALM: Advancing protein interaction prediction with AI and language models

Proteins are the building blocks of life, involved in virtually every biological process. Understanding how proteins interact with each other is crucial for deciphering the complexities of cellular functions, and has significant implications for drug development and the treatment of diseases.

24 Jun 2024

Antisense RNA acts as a cellular 'booster' for gene expression, study finds

The function of non-coding RNA in the cell has long been a mystery to researchers. Unlike coding RNA, non-coding RNA does not produce proteins – yet it exists in large quantities.

24 Jun 2024

Will it soon be possible for doctors to use AI to detect and diagnose cancer?

Researchers developed binary and multiclass machine learning models to distinguish cancer from non-cancerous tissue samples.

24 Jun 2024

JAK1 inhibition and Anti-PD1 therapy enhance outcomes in advanced lung cancer

Adding an anti-inflammatory drug to anti-PD1 checkpoint inhibitor immunotherapy has shown great promise as a new strategy against advanced lung cancer, based on results from a small clinical trial led by investigators at the Abramson Family Cancer Center at the University of Pennsylvania Perelman School of Medicine.

21 Jun 2024

Hematopoietic stem cells in the bone marrow age differently in genetically identical mice

Our bone marrow - the fatty, jelly-like substance inside our bones - is an unseen powerhouse quietly producing 500 billion new blood cells every day.

21 Jun 2024

Combination therapy shows great promise as a new strategy against advanced lung cancer

21 Jun 2024

Integrated cellular map of heart cells unlocks cardiac fibrosis process

Scientists at the Victor Chang Cardiac Research Institute in Australia have produced a first of its kind integrated map of heart cells which unlocks the process of cardiac fibrosis – a major cause of heart failure.

21 Jun 2024

UT Health San Antonio researcher wins NIH grant to investigate alcohol-associated liver disease

Liver transplants associated with alcohol-related disease are growing at a rapid pace, shifting research to address pathologies behind the ailments in light of a limited supply of organ donors.

21 Jun 2024

Pacific Northwest Research Institute uncovers hidden DNA mechanisms of rare genetic diseases

Researchers at the Pacific Northwest Research Institute (PNRI) and collaborating institutions have made a groundbreaking discovery that could significantly advance our understanding of genomic disorders.

21 Jun 2024

How random gene activity shapes lifespan in C. elegans

Why do some people live for longer than others? The genes in our DNA sequence are important, helping avoid disease or maintain general health, but differences in our genome sequence alone explain less than 30% of the natural variance of human life expectancy.

21 Jun 2024

Restoring youthful TERT levels reverses aging phenotypes in preclinical models

Researchers at The University of Texas MD Anderson Cancer Center have demonstrated that therapeutically restoring 'youthful' levels of a specific subunit of the telomerase enzyme can significantly reduce the signs and symptoms of aging in preclinical models.

21 Jun 2024

Study reveals critical role of ADGRF5 in maintaining glomerular filtration barrier integrity

Glomerulus, the fundamental filtering unit of the kidney, is an intricate network of capillaries - small blood vessels that regulate the movement of ions, water, and metabolites while maintaining impermeability to essential macromolecules such as proteins.

21 Jun 2024

New insights into signaling pathways and resistance mechanisms in colorectal cancer

Colorectal cancer (CRC) is a leading cause of cancer-related deaths worldwide. The complexity of its pathogenesis, involving genetic mutations, dysregulated signaling pathways, and compromised immune surveillance, presents significant challenges for effective treatment.

21 Jun 2024

Study links lifetime cannabis use with substance use, mood disorders, celiac, and infectious diseases

Researchers identify genetic loci associated with lifetime and frequency of cannabis use.

21 Jun 2024

B Cell News and Research

Enhancing adoptive T-cell therapy with nanowire innovation

New study in rhesus macaques offers early intervention window for Alzheimer's

Primitive endoderm in early embryos may be key to creating new effective fertility treatments

Study reveals early immune responses to SARS-CoV-2, offering insights for future COVID-19 treatments

Bridging knowledge and confidence to increase skin self-examinations

Study sheds light on the role of signaling pathway in the brain to prevent neuroinflammation

DiffPALM: Advancing protein interaction prediction with AI and language models

Antisense RNA acts as a cellular 'booster' for gene expression, study finds

Will it soon be possible for doctors to use AI to detect and diagnose cancer?

JAK1 inhibition and Anti-PD1 therapy enhance outcomes in advanced lung cancer

Hematopoietic stem cells in the bone marrow age differently in genetically identical mice

Combination therapy shows great promise as a new strategy against advanced lung cancer

Integrated cellular map of heart cells unlocks cardiac fibrosis process

UT Health San Antonio researcher wins NIH grant to investigate alcohol-associated liver disease

Pacific Northwest Research Institute uncovers hidden DNA mechanisms of rare genetic diseases

How random gene activity shapes lifespan in C. elegans

Restoring youthful TERT levels reverses aging phenotypes in preclinical models

Study reveals critical role of ADGRF5 in maintaining glomerular filtration barrier integrity

New insights into signaling pathways and resistance mechanisms in colorectal cancer

Study links lifetime cannabis use with substance use, mood disorders, celiac, and infectious diseases

Using single B cell screening to boost antibody discovery eBook

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

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