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SHINE trial reveals risks of high blood sugar in post-thrombolysis stroke care

An ambitious, nationwide clinical trial led by UVA Health's Karen Johnston, MD, has provided doctors with long-needed insights into the importance of managing stroke patients' blood sugar after treatment with clot-busting therapy.

13 May 2024

Study shows limited effectiveness of common local anesthetic

Liposomal bupivacaine was launched on the market twelve years ago to provide long-lasting local control of pain.

13 May 2024

New insights into Chaga mushroom's mechanisms for fighting oral cancer

The mechanisms behind the anti-tumor activity of Chaga mushroom extracts in HSC-4 human oral cancer cells.

13 May 2024

First responders, veterans hail benefits of psychedelic drugs as California debates legalization

Wade Trammell recalls the time he and his fellow firefighters responded to a highway crash in which a beer truck rammed into a pole, propelling the truck's engine through the cab and into the driver's abdomen.

13 May 2024

Yogic practices enhance heart health and functional capacity in heart failure patients

Yoga focused on breathing, meditation, and relaxation is linked with symptom improvement in patients with heart failure, according to research presented today at Heart Failure 2024, a scientific congress of the European Society of Cardiology.

13 May 2024

Long-term Finnish study explores the association between premature menopause and mortality

Women who enter menopause before the age of 40 are more likely to die young, but may lower their risk with hormone therapy, according to research presented at the 26th European Congress of Endocrinology in Stockholm.

13 May 2024

Enhanced weight loss outcomes with GLP-1 analogues and bupropion/naltrexone combination

A study explores the additive effects of combining GLP-1 analog with bupropion/naltrexone on weight loss, finding potential benefits even for those initially unresponsive to monotherapy.

13 May 2024

New partnership addresses key challenges for regulating digital mental health technologies

An MHRA and NICE partnership, funded by Wellcome, is addressing key challenges for regulating and evaluating digital mental health technologies (DMHTs) with input from patients, the public and mental health professionals.

11 May 2024

Genetic variant increases heart failure risk and decreases longevity in Black Americans

Researchers at Brigham and Women’s Hospital and Duke University showed that a genetic variant, present in 3-4% of self-identified Black individuals in the U.S., increases the risk for both heart failure and death and contributes to significant decreases in longevity at the population level.

11 May 2024

Expanding treatment horizons for hypermutated urothelial carcinomas beyond immunotherapy

A new editorial paper was published in Oncoscience (Volume 11) on April 25, 2024, entitled, "Therapeutic opportunities for hypermutated urothelial carcinomas beyond immunotherapy."

10 May 2024

DoD grant awarded for investigating alternative polyadenylation in prostate cancer

A team led by Dr. Eddie Imada, assistant professor of research in pathology and laboratory medicine, has been awarded a three-year, $1.5 million United States Department of Defense grant for research on a cellular process called alternative polyadenylation and its role in prostate cancer.

10 May 2024

Drug repurposing breakthrough: varespladib curbs snakebite-induced necrosis

Researchers discovered that venom toxins from African spitting cobras cause severe dermonecrosis, highlighting the need for targeted treatments like the repurposed drug varespladib.

9 May 2024

Combination immunotherapy treatment enhances immune response for people with malignant gliomas

Investigators at the UCLA Health Jonsson Comprehensive Cancer Center have pinpointed a combination immunotherapy treatment that enhances the immune response for people with malignant gliomas, an aggressive type of brain tumor that is fast growing and difficult to treat.

9 May 2024

Ketogenic diet a potential therapy for autism by reshaping gut bacteria and brain inflammation

Modified ketogenic diet modulates gut microbiome, inflammatory markers, and brain-related miRNAs in autistic children, correlating with improved behavioral symptoms. The diet increases beneficial gut bacteria and reduces inflammatory cytokines and BDNF levels.

9 May 2024

Enhancing the ability of natural killer cells to combat hematologic malignancies

A new study reveals a groundbreaking approach to immunotherapy, demonstrating that blocking the interaction between the CD300A receptor and phosphatidylserine (PS) significantly enhances the ability of human natural killer (NK) cells to lyse hematologic malignancies (HMs).

9 May 2024

Relaxation interventions can be offered to lactating parents who would like to improve milk supply and increase well-being

A recent study in JAMA Pediatrics explored the utility of relaxation therapy in increasing milk production in human mothers.

9 May 2024

Novel bispecific antibodies show promise against evolving SARS-CoV-2 variants

Researchers developed bispecific antibodies targeting both the N-terminal and receptor binding domains of SARS-CoV-2, demonstrating significant neutralization across various Omicron variants, suggesting potential for new COVID-19 treatments.

9 May 2024

USC study unveils iron as key driver of lung inflammation in allergic asthma

New USC research shows that iron serves as a gas pedal driving certain immune cells that cause inflammation in the lungs during an allergic asthma attack – and blocking or limiting iron may reduce the severity of symptoms.

8 May 2024

Researchers enhance CAR-T cells to target solid tumors

Researchers at the National Cancer Institute-designated Montefiore Einstein Comprehensive Cancer Center (MECCC) have shown that a breakthrough therapy for treating blood cancers can be adapted to treat solid tumors - an advance that could transform cancer treatment.

8 May 2024

AVAnT1A study: Investigating early COVID-19 vaccination and type 1 diabetes risk in children

Type 1 diabetes is an autoimmune disease that leads to disrupted glucose metabolism. It requires lifelong insulin therapy.

8 May 2024

Therapy News and Research

SHINE trial reveals risks of high blood sugar in post-thrombolysis stroke care

Study shows limited effectiveness of common local anesthetic

New insights into Chaga mushroom's mechanisms for fighting oral cancer

First responders, veterans hail benefits of psychedelic drugs as California debates legalization

Yogic practices enhance heart health and functional capacity in heart failure patients

Long-term Finnish study explores the association between premature menopause and mortality

Enhanced weight loss outcomes with GLP-1 analogues and bupropion/naltrexone combination

New partnership addresses key challenges for regulating digital mental health technologies

Genetic variant increases heart failure risk and decreases longevity in Black Americans

Expanding treatment horizons for hypermutated urothelial carcinomas beyond immunotherapy

DoD grant awarded for investigating alternative polyadenylation in prostate cancer

Drug repurposing breakthrough: varespladib curbs snakebite-induced necrosis

Combination immunotherapy treatment enhances immune response for people with malignant gliomas

Ketogenic diet a potential therapy for autism by reshaping gut bacteria and brain inflammation

Enhancing the ability of natural killer cells to combat hematologic malignancies

Relaxation interventions can be offered to lactating parents who would like to improve milk supply and increase well-being

Novel bispecific antibodies show promise against evolving SARS-CoV-2 variants

USC study unveils iron as key driver of lung inflammation in allergic asthma

Researchers enhance CAR-T cells to target solid tumors

AVAnT1A study: Investigating early COVID-19 vaccination and type 1 diabetes risk in children

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