Clinical Trial News and Research

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Diabetes remission diet can provide blood pressure control, reduce the need for anti-hypertensive drugs

New research has shown that if people achieve and maintain substantial weight loss to manage their type 2 diabetes, many can also effectively control their high blood pressure and stop or cut down on their anti-hypertensive medication.

31 May 2021

Waking up just one hour earlier can reduce risk of major depression, indicates study

Waking up just one hour earlier could reduce a person's risk of major depression by 23%, suggests a sweeping new genetic study published May 26 in the journal JAMA Psychiatry.

29 May 2021

Exoskeleton-assisted walking helps people with spinal cord injury evacuate stool more efficiently

A team of researchers has shown that physical intervention plans that included exoskeleton-assisted walking helped people with spinal cord injury evacuate more efficiently and improved the consistency of their stool.

29 May 2021

New LNP-based mRNA vaccine candidate protects against lethal SARS-CoV-2 in preclinical trials

A new study, published in Nano Letters, describes an effective new COVID-19 vaccine candidate based on a messenger ribonucleic acid (mRNA) platform.

28 May 2021

COLCORONA study shows that colchicine can reduce complications in certain COVID-19 patients

The Montreal Heart Institute announces that the COLCORONA study results are published today in The Lancet Respiratory Medicine.

28 May 2021

Study: Specific diet, lifestyle interventions may reverse epigenetic aging in healthy adult males

Aging published "Potential reversal of epigenetic age using a diet and lifestyle intervention: a pilot randomized clinical trial" which reported on a randomized controlled clinical trial conducted among 43 healthy adult males between the ages of 50-72.

28 May 2021

Reducing COVID-19 burden with monoclonal antibodies and vaccination

Researchers in the United States, the UK and France have shown that using antiviral monoclonal antibodies in combination with vaccination can be expected to suppress the transmission of severe acute respiratory syndrome coronavirus 2 (SARS CoV-2) and reduce the burden of coronavirus disease 2019 (COVID-19) more than vaccination alone.

26 May 2021

New article sheds more light on myopia control efficacy

A new paper that has been accepted for publication in Ophthalmic & Physiological Optics, the peer-reviewed journal of The College of Optometrists (UK), furthers understanding of myopia control efficacy in the context of normal childhood eye growth. Axial Length Targets for Myopia Control (Chamberlain P, et al.) is now available online via Open Access.

26 May 2021

A behavioral health care app to address COVID-related health disparities in racial, ethnic populations

A University of Houston researcher is developing a behavioral health care app to address COVID-related health disparities in racial and ethnic populations, where health inequality has been magnified during the pandemic.

26 May 2021

Researchers to conduct Phase 1 gene therapy trial to treat Alzheimer's disease

The National Institute on Aging (NIA), part of the National Institutes of Health, has awarded a $5 million grant to researchers at University of California San Diego School of Medicine to conduct a first-in-human Phase 1 clinical trial of a gene therapy for treating Alzheimer's disease (AD) or Mild Cognitive Impairment (MCI), a condition that often precedes full-blown dementia.

26 May 2021

Altered blood flow in the brain may cause symptoms of Parkinson's disease

Patients who suffer from REM sleep behavior disorder have altered blood flow in the brain, which can lead to a lack of oxygen in the brain tissue. In the long term, this may cause symptoms of Parkinson's disease. This is shown by research from Aarhus University and Aarhus University Hospital.

26 May 2021

Study shows how rare but serious post-COVID-19 complication develops in children, adolescents

A multidisciplinary team from MassGeneral Hospital for Children (MGHfC), Brigham and Women's Hospital and other institutions have identified the mechanism of how an extremely rare but serious post-COVID-19 complication develops in children and adolescents.

26 May 2021

Cognitive-behavioural therapy can reduce pain during intercourse

One in five women experience pain during intercourse. The latest edition of the Diagnostic and Statistical Manual of Mental Disorders, the bible of American psychiatrists, lists it under "genito-pelvic pain or penetration disorder."

26 May 2021

Researchers develop a novel probiotic formulation with high anti-SARS-CoV-2 potency

A team of international scientists recently conducted a randomized clinical trial to assess the safety and efficacy profiles of a novel probiotic formulation in symptomatic coronavirus disease 2019 (COVID-19) patients. The findings indicate that the probiotic formulation is highly effective in reducing symptom severity in COVID-19 patients without causing any adverse events.

25 May 2021

New technology makes it easier to diagnose neurodegenerative diseases

A new combination of optical coherence tomography (OCT), adaptive optics and deep neural networks should enable better diagnosis and monitoring for neuron-damaging eye and brain diseases like glaucoma.

25 May 2021

UIC leads multi-center collaborative to help communities affected by COVID-19

The University of Illinois Chicago has been selected by the National Institutes of Health as the principal site of a multi-center collaborative in the Chicago area that will bolster research and outreach to help communities disproportionately affected by COVID-19.

25 May 2021

Do mixed COVID-19 vaccines provide immunity?

The initial results of the CombivacS trial found that the antibody levels in individuals increased by 150 times when the Pfizer messenger ribonucleic acid (mRNA) vaccine was given after a first dose of the AstraZeneca severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine, with only mild common side effects.

24 May 2021

Could saffron be an effective supplement for helping manage COVID-19?

A new study, published in the journal Cell Press, explores the potential use of saffron (Crocus sativus L.) as a drug supplement for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of coronavirus disease 2019 (COVID-19).

24 May 2021

Landmark study confirms that controlled blood pressure is key to prevent stroke, heart disease

Follow-up data from the landmark SPRINT study of the effect of high blood pressure on cardiovascular disease have confirmed that aggressive blood pressure management -- lowering systolic blood pressure to less than 120 mm Hg -- dramatically reduces the risk of heart disease, stroke, and death from these diseases, as well as death from all causes, compared to lowering systolic blood pressure to less than 140 mm Hg.

22 May 2021

Australian discovery could speed up SARS-CoV-2 vaccine development

To address this gap, researchers from Australia recently examined the relationship between levels of in vitro neutralization and the observed protection obtained from SARS-CoV-2 infection. They used data from 7 currently available vaccines and convalescent cohorts. Their research is published in the journal Nature Medicine.

22 May 2021

Clinical Trial News and Research

Diabetes remission diet can provide blood pressure control, reduce the need for anti-hypertensive drugs

Waking up just one hour earlier can reduce risk of major depression, indicates study

Exoskeleton-assisted walking helps people with spinal cord injury evacuate stool more efficiently

New LNP-based mRNA vaccine candidate protects against lethal SARS-CoV-2 in preclinical trials

COLCORONA study shows that colchicine can reduce complications in certain COVID-19 patients

Study: Specific diet, lifestyle interventions may reverse epigenetic aging in healthy adult males

Reducing COVID-19 burden with monoclonal antibodies and vaccination

New article sheds more light on myopia control efficacy

A behavioral health care app to address COVID-related health disparities in racial, ethnic populations

Researchers to conduct Phase 1 gene therapy trial to treat Alzheimer's disease

Altered blood flow in the brain may cause symptoms of Parkinson's disease

Study shows how rare but serious post-COVID-19 complication develops in children, adolescents

Cognitive-behavioural therapy can reduce pain during intercourse

Researchers develop a novel probiotic formulation with high anti-SARS-CoV-2 potency

New technology makes it easier to diagnose neurodegenerative diseases

UIC leads multi-center collaborative to help communities affected by COVID-19

Do mixed COVID-19 vaccines provide immunity?

Could saffron be an effective supplement for helping manage COVID-19?

Landmark study confirms that controlled blood pressure is key to prevent stroke, heart disease

Australian discovery could speed up SARS-CoV-2 vaccine development

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