Efficacy News and Research

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Study opens up new possible treatment methods for patients with urinary tract infections

Patients who have indwelling urinary catheters often suffer from urinary tract infections, which can be difficult to treat.

22 Jul 2022

Alzheimer's disease and anti-amyloid therapeutic approaches

An estimated 50 million people around the world have Alzheimer's disease (AD), and perhaps twice that number are unknowingly "incubating" the disease during its long presymptomatic period.

21 Jul 2022

A different approach to build a more durable, broadly effective COVID-19 vaccine

Researchers at University of California San Diego School of Medicine, with colleagues elsewhere, describe a different way to build a COVID-19 vaccine, one that would, in theory, remain effective against new and emerging variants and could be taken as a pill, by inhalation or other delivery methods.

21 Jul 2022

Phase 2a clinical trial describes safety and efficacy of dendrimer nanotherapy in severe COVID-19 patients

A multicenter, randomized, placebo-controlled phase 2a clinical trial has recently been conducted to evaluate the efficacy of a nanotherapeutic compound OP-101 in treating severe COVID-19 patients.

21 Jul 2022

FDA clears IND application for MD Anderson-sponsored Phase I clinical study of OBX-115 therapy

The University of Texas MD Anderson Cancer Center and Obsidian Therapeutics, Inc. today announced Food and Drug Administration (FDA) clearance of an Investigational New Drug (IND) application for an MD Anderson-sponsored Phase I clinical study of OBX-115, Obsidian's lead engineered tumor infiltrating lymphocyte (TIL) therapy candidate.

21 Jul 2022

AbbVie Submits Marketing Authorization Application to EMA for Atogepant for the Preventive Treatment of Migraine

AbbVie today announced it has submitted a marketing authorization application (MAA) to the European Medicines Agency (EMA) for atogepant for the prophylaxis of migraine in adult patients who have at least four migraine days per month.

From AbbVie 21 Jul 2022

Myocardial fibrosis linked to worse cardiovascular outcomes in patients with hypertension

A recent study conducted by the National Heart Centre Singapore (NHCS) discovered that myocardial fibrosis is associated with worse cardiovascular outcomes in patients with hypertension. Myocardial fibrosis is an important prognostic marker in the development of adverse cardiovascular events, such as heart failure and death.

21 Jul 2022

Kessler Foundation researchers receive NJHF grants to advance research in neurological disabilities

Each year, New Jersey Health Foundation (NJHF) accepts applications for grants for research projects that demonstrate exciting potential to help scientists leverage their preliminary findings to qualify for additional funding to advance their research. This year, grants were awarded to three researchers at Kessler Foundation.

21 Jul 2022

Is monkeypox a global public-health emergency?

A summary of available knowledge on the monkeypox virus including pathogenicity, risk to the human population, and strategies that can help limit its spread.

20 Jul 2022

High-level resistance of SARS-CoV-2 BA.4 against neutralizing antibodies

Researchers evaluates the sensitivity of BA.4 in both vaccinated and unvaccinated individuals infected with the SARS-CoV-2 variants.

20 Jul 2022

Fourth dose of Pfizer mRNA COVID vaccine protective against variants and symptomatic infection

Researchers evaluate the efficacy of three- and four-dose regimens of a mRNA-based COVID-19 vaccine in reducing the risk of symptomatic infection.

20 Jul 2022

How does vitamin D supplementation impact COVID-19 vaccine efficacy?

Researchers assessed the impact of vitamin D supplementation on the efficacy of SARS-CoV-2 vaccines.

20 Jul 2022

Nanotherapeutic compound may help treat inflammation, brain injury in patients with severe COVID-19

An anti-inflammatory compound may have the potential to treat systemic inflammation and brain injury in patients with severe COVID-19 and significantly reduce their chances of death, according to a new study from UTHealth Houston and other institutions.

20 Jul 2022

Scientists introduce SARS-CoV-2 phenotype screening for identifying novel antiviral drugs

Researchers introduced a phenotypic screening assay for identifying compounds with SARS-CoV-2 inhibition potential based on caspase 3/7 activation.

20 Jul 2022

The clinical, epidemiological, and evolutionary consequences of a potential SARS-CoV-2-related bat virus spillover into humans

A team of scientists from France has recently described the epidemiological and clinical consequences of a bat sarbecovirus infection in humanized mice.

20 Jul 2022

Efficacy News and Research

Study opens up new possible treatment methods for patients with urinary tract infections

Alzheimer's disease and anti-amyloid therapeutic approaches

A different approach to build a more durable, broadly effective COVID-19 vaccine

Phase 2a clinical trial describes safety and efficacy of dendrimer nanotherapy in severe COVID-19 patients

FDA clears IND application for MD Anderson-sponsored Phase I clinical study of OBX-115 therapy

AbbVie Submits Marketing Authorization Application to EMA for Atogepant for the Preventive Treatment of Migraine

Myocardial fibrosis linked to worse cardiovascular outcomes in patients with hypertension

Kessler Foundation researchers receive NJHF grants to advance research in neurological disabilities

Is monkeypox a global public-health emergency?

High-level resistance of SARS-CoV-2 BA.4 against neutralizing antibodies

Fourth dose of Pfizer mRNA COVID vaccine protective against variants and symptomatic infection

How does vitamin D supplementation impact COVID-19 vaccine efficacy?

Nanotherapeutic compound may help treat inflammation, brain injury in patients with severe COVID-19

Scientists introduce SARS-CoV-2 phenotype screening for identifying novel antiviral drugs

The clinical, epidemiological, and evolutionary consequences of a potential SARS-CoV-2-related bat virus spillover into humans

Novavax COVID-19 vaccine now available in the U.S. to protect against severe disease

What is the role of a niclosamide-based organic/inorganic hybrid in the suppression of SARS-CoV-2 infections?

Neutralizing activity of skin-patch delivered subunit vaccine against SARS-CoV-2 variants

Review: No clear evidence that serotonin levels are responsible for depression

Chewing gum containing plant-based antiviral proteins neutralizes SARS-CoV-2 and influenza viruses

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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