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Asymptomatic HIV-infected newborns may benefit from early drug treatment

Identifying and treating HIV-infected newborns is a race against the clock, according to a study from the Stanford University School of Medicine and Lucile Packard Children's Hospital.

10 May 2005

Vaccine against Alzheimer's disease may still be on the cards

A new, but modified, trial of an Alzheimer's vaccine has begun in the U.S. despite an earlier one being abandoned in 2002 due to safety concerns.

10 May 2005

New laser technology for more precise cancer treatments

Tom Cowan’s team is thinking smaller, but with big impact. Particle accelerators are a key research tool in a high energy physicist’s arsenal, but they take up a lot of space - miles and miles of it. But at the University of Nevada, Reno, smaller is better.

10 May 2005

Discovery of a fundamental new route into cells may lead to new methods of drug delivery

Researchers from The University of Queensland’s Institute for Molecular Bioscience (IMB), and the Centre for Microscopy and Microanalysis used electron microscopy to uncover new structures, 100,000th of a mm in size, which are involved in the very first step of particle and nutrient uptake into cells.

10 May 2005

No glass ceiling for women when it comes to dying from heart disease, say experts

While many of us assume that heart disease mainly strikes men, the fact is 12,000 Australian women die each year from illnesses like stroke, heart attack and heart failure - that's four and a half times the number of lives claimed by breast cancer.

10 May 2005

Research offers new molecular approaches to therapies for the most deadly cancers

Researchers at Wake Forest University Baptist Medical Center have found promising new molecular targets and treatment approaches for some of the most malignant brain tumors.

10 May 2005

Cytogen Corporation and Dowpharma collaborate to create a targeted oncology product designed to treat prostate and other cancers

Under the agreement, Dowpharma's proprietary MeO-DOTA bifunctional chelant technology will be used to radiolabel Cytogen's prostate-specific membrane antigen (PSMA) antibody with a therapeutic radionuclide. PSMA is a protein highly expressed on the surface of prostate cancer cells and the neovasculature of many solid tumors.

10 May 2005

Laboratory model of immune system overcomes ethical constraints on studies of hematopoietic stem cells in humans

Scientists at St. Jude Children’s Research Hospital have joined with colleagues at several other institutions to develop a laboratory model of the human immune system. This model will allow scientists to study ways for improving the results of hematopoietic stem cell (HSC) transplantation without putting patients at risk.

10 May 2005

Combining behavior modification therapy with medication is the most effective way to improve the behavior of many ADHD children

In fact, when the two are combined, the study showed, the amount of medication required to achieve the same results as use of medication alone can be reduced by two-thirds.

10 May 2005

Scientists inhibit tumor formation

By studying mice with skin cancer, researchers at the Huntsman Cancer Institute at the University of Utah discovered a way to inhibit a mutant gene found in up to 30 percent of human tumors.

9 May 2005

New study suggests Pioglitazone HCl may significantly improve key predictors of cardiovascular risk

Study results published in the May 17th issue of Circulation, the journal of the American Heart Association, found that the diabetes medication pioglitazone HCl reduced carotid artery intima-media thickness (IMT). Patients taking pioglitazone also experienced significant reductions in insulin resistance, C-reactive protein (a marker for inflammation) and blood pressure, all of which contribute to the overall risk for cardiovascular disease.

9 May 2005

As science gets wiser, so do the bugs

As science gets wiser, so do the bugs. The rates of drug-resistant bacteria infecting patients in the community and in the hospital have been increasing steadily in recent years, according to two new studies in the June 15 issue of Clinical Infectious Diseases.

9 May 2005

Clues about how alcoholic behavior is “switched” on

As part of an ongoing effort to understand the biochemical basis of alcohol abuse, scientists at the U.S. Department of Energy’s Brookhaven National Laboratory have published two studies on how modulating receptors for dopamine - a chemical “signaler” in the brain’s reward circuits - affects drinking behavior in mice and rats.

9 May 2005

Metabolic syndrome costing four times that for all other patients

It is well known that hypertension, diabetes, and obesity are each taking a toll on Americans' health, but according to a new analysis, metabolic syndrome, a condition characterized by a combination of these and/or other risk factors, is fast becoming one of the nation's costliest health concerns.

9 May 2005

Study calls for earlier use of ICDs in patients diagnosed with cardiomyopathy

A study presented today at the Late Breaking Clinical Trials presentations at the Heart Rhythm Society's Annual Scientific Sessions in New Orleans found that implantable cardiac defibrillators (ICD) benefit patients with recently diagnosed cardiomyopathy, a disease that affects the heart muscle's ability to pump and can lead to heart failure.

8 May 2005

Promising new molecular targets and treatment approaches for some of the most malignant brain tumors

The first study identified a protein that seems to control the malignant features of brain tumor cells, suggesting a new treatment target for anti-cancer drugs. Researchers found that a little-known protein called Fra-1 was effective in controlling vascular endothelial growth factor D, a factor that promotes the growth of new blood vessels in most malignant brain tumors.

8 May 2005

Survey of ED doctors shows team-based stroke care, risk-reducing measures, needed to increase use of tPA

Forty percent of emergency physicians say they're unlikely to give stroke patients the only FDA-approved drug shown to improve their prognosis, even in an ideal setting, mostly because of the fear of causing brain bleeding.

5 May 2005

Research is first to test effectiveness of a new patch for treating ADHD

A new University at Buffalo study of treatments for children with attention deficit hyperactivity disorder (ADHD) has found that combining behavior modification therapy with medication is the most effective way to improve the behavior of many ADHD children.

5 May 2005

Serious concerns about the use of morphine in heart patients

While patients hospitalized for a heart attack have long been treated with morphine to relieve chest pain, an analysis by researchers from the Duke Clinical Research Institute has shown that these patients have almost a 50 percent higher risk of dying.

5 May 2005

WHO’s goal to provide life-long antiretroviral therapy to 3 million people with HIV/AIDS at risk of failing

Lack of financial resources, staff, and commitment from key countries, may hamper WHO’s goal to provide life-long antiretroviral therapy to 3 million people with HIV/AIDS in developing countries by the end of 2005 (3 by 5), states an editorial in this week’s issue of The Lancet.

4 May 2005

Therapy News and Research

Asymptomatic HIV-infected newborns may benefit from early drug treatment

Vaccine against Alzheimer's disease may still be on the cards

New laser technology for more precise cancer treatments

Discovery of a fundamental new route into cells may lead to new methods of drug delivery

No glass ceiling for women when it comes to dying from heart disease, say experts

Research offers new molecular approaches to therapies for the most deadly cancers

Cytogen Corporation and Dowpharma collaborate to create a targeted oncology product designed to treat prostate and other cancers

Laboratory model of immune system overcomes ethical constraints on studies of hematopoietic stem cells in humans

Combining behavior modification therapy with medication is the most effective way to improve the behavior of many ADHD children

Scientists inhibit tumor formation

New study suggests Pioglitazone HCl may significantly improve key predictors of cardiovascular risk

As science gets wiser, so do the bugs

Clues about how alcoholic behavior is “switched” on

Metabolic syndrome costing four times that for all other patients

Study calls for earlier use of ICDs in patients diagnosed with cardiomyopathy

Promising new molecular targets and treatment approaches for some of the most malignant brain tumors

Survey of ED doctors shows team-based stroke care, risk-reducing measures, needed to increase use of tPA

Research is first to test effectiveness of a new patch for treating ADHD

Serious concerns about the use of morphine in heart patients

WHO’s goal to provide life-long antiretroviral therapy to 3 million people with HIV/AIDS at risk of failing

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