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BetterYou Magnesium Oil spray relieves migraine pain in 43-year old mum

A 43-year old mum of one from Bristol, who suffered from frequent painful migraines for almost a decade has found relief thanks to BetterYou™ Magnesium Oil spray.

From BetterYou Ltd 13 May 2016

NeuroDerm starts patient enrollment in long-term safety study of ND0612 for treatment of Parkinson’s disease

NeuroDerm Ltd., a clinical stage pharmaceutical company developing drugs for central nervous system disorders, today announced the start of patient enrollment in a long-term safety study (trial 012) of the company’s continuously administered subcutaneous levodopa/carbidopa formulation used in both ND0612H and ND0612L.

13 May 2016

Clinical study shows sitagliptin drug not effective in treating NAFLD

A diabetes medication described in some studies as an effective treatment for nonalcoholic fatty liver disease (NAFLD) works no better than a placebo, report researchers at University of California San Diego School of Medicine, after conducting the first randomized, double-blind, controlled clinical trial of sitagliptin, an oral antihyperglycemic marketed by Merck & Co. under the name Januvia.

13 May 2016

Could oral supplements affect teenage behavior? An interview with Prof. Stein and Dr Tammam

We wanted to see whether supplementing the diet of disadvantaged adolescents with the omega 3 polyunsaturated acids, EPA & DHA, vitamins and minerals over a school term might improve their antisocial behaviour, which usually gets worse during a term.

12 May 2016

Computerized decision support tool can assist physicians in prescribing stroke prevention therapy

Physician-researchers in the College of Medicine at the University of Cincinnati have developed a computerized decision support tool that uses a combination of patient information and characteristics to assist physicians and patients with decisions about blood thinning treatment to prevent strokes in individuals with atrial fibrillation.

12 May 2016

Scientists discover reliable marker to spot CAFs in oral cancer tissues

For the first time, researchers have identified a reliable marker (PDGFRβ) to detect carcinoma-associated fibroblasts (cells within the tumor that encourage growth and metastasis) (CAFs) in oral cancer tissues. With this discovery, anti-PDGFRβ treatment could soon be combined with existing tumor treatments to provide a more effective cancer therapy.

11 May 2016

Repeat, low-dose ketamine infusions may quickly reduce suicidal thoughts in depressed outpatients

Repeat intravenous treatment with low doses of the anesthetic drug ketamine quickly reduced suicidal thoughts in a small group of patients with treatment-resistant depression.

11 May 2016

Genetic mutations may be key culprit behind ciliopathies, study shows

Scientists have identified genetic mutations that appear to be a key culprit behind a suite of birth defects called ciliopathies, which affect an estimated 1 in 1,000 births.

11 May 2016

Oral regimens could offer simple solution for severe hyperglycaemia

Study findings indicate that oral treatments could offer a simpler alternative to upfront insulin for patients who have severe hyperglycaemia at the time of diagnosis with Type 2 diabetes.

10 May 2016

Pathogen-selective approach to antibiotic development less disruptive to gut microbiome

St. Jude Children's Research Hospital scientists report the first evidence that a pathogen-specific antibiotic was less disruptive to the gut microbiome than broad-spectrum antibiotics.

10 May 2016

NYUCD awarded $1.6M grant to explore biological and physiological effects of e-cig use on oral health

The National Institute of Dental and Craniofacial Research, a division of the National Institutes of Health, has awarded NYU College of Dentistry Professors Deepak Saxena, MS, PhD, and Xin Li, PhD, a four-year $1.6M NIDCR grant to study the biological and physiological effects of electronic cigarette aerosol mixtures on oral health.

10 May 2016

Novel anticoagulants on ‘as-needed basis’ could be safe alternative to lowering stroke risk

Patients with atrial fibrillation (AF), a rapid irregular heartbeat caused by pooling blood in the heart which can lead to heart failure and stroke, are often treated with an ablation, a minimally invasive procedure used to remove the tissue which causes the pooled blood.

9 May 2016

More evidence for combination therapy benefits in PAH

Another meta-analysis adds to evidence of increased benefits for patients with pulmonary arterial hypertension who are given combination therapy.

6 May 2016

Female sex hormone estradiol may protect women against sexually transmitted viral infections

A team of researchers led by McMaster University's Charu Kaushic has revealed for the first time how estradiol, a female sex hormone present during the menstrual cycle and found in oral contraceptives, may work to protect women against sexually transmitted viral infections.

6 May 2016

Studies show mango consumption may contribute to protective health effects

Four new studies surrounding the effects of mango consumption suggest this superfruit has the potential to help combat adverse effects associated with high fat diets and obesity (animal study), as well inhibit growth of fat cells (anti-lipogenic properties in an in-vivo study), slow advancement of breast cancer tumors (animal study), as well as improve regularity and decrease inflammation associated with constipation (human subject study).

6 May 2016

UA researchers one step closer to preventing asthma in children

Efforts to improve the health of children at increased risk for asthma will receive a major boost with the launch of a new University of Arizona Health Sciences-led, federally funded national clinical study. For Fernando D. Martinez, MD, and his colleagues at the UA Asthma and Airway Disease Research Center, this study follows 30 years of research to prevent and cure this chronic disease.

6 May 2016

Bayer-new phase 3 liver cancer data

Bayer has announced that a Phase III trial evaluating its oncology compound Stivarga® (regorafenib) tablets for the treatment of patients with unresectable hepatocellular carcinoma (HCC) has met its primary endpoint of a statistically significant improvement in overall survival. The study, called RESORCE, evaluated the efficacy and safety of regorafenib in patients with HCC whose disease has progressed after treatment with sorafenib. The safety and tolerability were generally consistent with the known profile of regorafenib. Detailed efficacy and safety analyses from this study are expected to be presented at an upcoming scientific congress.

4 May 2016

Study estimates 30% of outpatient oral antibiotic prescription in the U.S as inappropriate

An estimated 30 percent of outpatient oral antibiotic prescriptions in the U.S. in 2010-2011 may have been inappropriate, findings that support the need for establishing a goal for outpatient antibiotic stewardship, according to a study appearing in the May 3 issue of JAMA.

4 May 2016

Oral administration of Jakinibs reduces Parkinson's disease pathogenesis in rat model

University of Alabama at Birmingham researchers report the first documentation that suppressing a key cell-signaling pathway in a rat model of Parkinson's disease reduces pathogenesis. Oral administration of AZD1480 — one of the JAK/STAT pathway inhibitors generally known as Jakinibs — lessened the destructive inflammation and nerve cell degradation in the area of the brain affected by Parkinson's.

4 May 2016

High doses of Imodium to self-treat opioid addictions could be extremely dangerous

The over-the-counter anti-diarrhea medication Imodium, or its key ingredient loperamide, is increasingly being abused by people attempting to self-treat their opioid addiction, with sometime fatal results.

4 May 2016

Oral News and Research

BetterYou Magnesium Oil spray relieves migraine pain in 43-year old mum

NeuroDerm starts patient enrollment in long-term safety study of ND0612 for treatment of Parkinson’s disease

Clinical study shows sitagliptin drug not effective in treating NAFLD

Could oral supplements affect teenage behavior? An interview with Prof. Stein and Dr Tammam

Computerized decision support tool can assist physicians in prescribing stroke prevention therapy

Scientists discover reliable marker to spot CAFs in oral cancer tissues

Repeat, low-dose ketamine infusions may quickly reduce suicidal thoughts in depressed outpatients

Genetic mutations may be key culprit behind ciliopathies, study shows

Oral regimens could offer simple solution for severe hyperglycaemia

Pathogen-selective approach to antibiotic development less disruptive to gut microbiome

NYUCD awarded $1.6M grant to explore biological and physiological effects of e-cig use on oral health

Novel anticoagulants on ‘as-needed basis’ could be safe alternative to lowering stroke risk

More evidence for combination therapy benefits in PAH

Female sex hormone estradiol may protect women against sexually transmitted viral infections

Studies show mango consumption may contribute to protective health effects

UA researchers one step closer to preventing asthma in children

Bayer-new phase 3 liver cancer data

Study estimates 30% of outpatient oral antibiotic prescription in the U.S as inappropriate

Oral administration of Jakinibs reduces Parkinson's disease pathogenesis in rat model

High doses of Imodium to self-treat opioid addictions could be extremely dangerous

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