Biomarker News and Research

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A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

Biomagnetics, LANL collaborate to develop device for tuberculosis diagnosis

Biomagnetics Diagnostics Corp., a developer of revolutionary technology for diagnostic systems for HIV, hepatitis, tuberculosis and malaria detection, today announced the signing of an agreement with Los Alamos National Security, LLC where Los Alamos National Laboratory's scientific and engineering staffs will attempt to identify new potential human tuberculosis biomarkers and will develop a validated assay to detect human tuberculosis using a currently known biomarker to be used in combination with the waveguide-based optical biosensor platform.

9 Jul 2010

Optics Express publishes special focus issue on lung cancer imaging research

Advanced imaging technologies that promise to improve the development of effective drugs to treat lung cancer are the focus of the current special issue of Optics Express, an open-access journal published by the Optical Society (OSA). Research featured in the special focus issue on Imaging in Diagnosis and Treatment of Lung Cancer outlines standardized approaches to measure and compare tumor size, as well as to validate the accuracy of such measurements under defined settings.

8 Jul 2010

Aethlon Medical files provisional patent on behalf of ESI for exosome detection assay

Aethlon Medical, Inc., the pioneer in developing therapeutic filtration devices to address infectious disease and cancer, announced today that it has filed a provisional patent on behalf of its wholly owned subsidiary Exosome Sciences, Inc. (ESI), relating to the development of an assay that will allow researchers to detect exosomes in blood and other fluids.

8 Jul 2010

MJFF announces $1.1M for projects to develop biomarker candidates for PD

The Michael J. Fox Foundation for Parkinson's Research today announced nearly $1.1 million for projects aimed at advancing the development of leading biomarker candidates for Parkinson's disease. The discovery and validation of biomarkers is of critical importance to increasing the speed and efficiency of PD therapeutic development, allowing scientists and clinicians to more accurately identify appropriate subjects for clinical studies, measure disease progression and monitor treatment effects in clinical trials.

7 Jul 2010

CPRIT grants RBM $3 million Company Commercialization Award to expand OncologyMAP program

Rules-Based Medicine, Inc. (RBM) today announced the Cancer Prevention and Research Institute of Texas (CPRIT) has granted it a Company Commercialization Award to expand and enhance the OncologyMAP™ program for discovery and development of novel diagnostic and prognostic cancer tests. The award of approximately $3 million will fund research and development to more than double the number of cancer-associated biomarker assays in RBM's new OncologyMAP™ product.

6 Jul 2010

Adeona completes $1 million equity financing and provides update on Zinthionein ZC clinical study

Adeona Pharmaceuticals, Inc., announced today that on July 6, 2010, it completed an equity financing of $1 million with a single institutional investor, Seaside 88, L.P. The financing involved the sale of 1,212,121 registered shares of common stock and no warrants. Enclave Capital served as placement agent and will receive a 7% cash commission and 5-year warrants to acquire 60,606 shares of Adeona at $1.32 per share. The use of proceeds is intended for general corporate purposes.

6 Jul 2010

Clusterin associated with development, severity and progression of Alzheimer's disease: Report

Higher concentrations of clusterin, a protein in the blood plasma, appears to be associated with the development, severity and progression of Alzheimer's disease, according to a report in the June issue of Archives of General Psychiatry, one of the JAMA/Archives journals.

6 Jul 2010

Metabolon unveils novel approach to identify patients at preterm delivery risk

Metabolon, Inc., the leader in global metabolism, biomarker discovery and analysis, announces the publication of "Metabolomics in premature labor: a novel approach to identify patients at risk for preterm delivery", in The Journal of Maternal-Fetal and Neonatal Medicine.

3 Jul 2010

Neogenix Oncology files patent application with USPTO for 16C3 antigen

Neogenix Oncology announced today that the company has filed a patent application with the U.S. Patent and Trade Office (USPTO) for the 16C3 antigen. The Company believes that this antigen is tumor specific for pancreatic and colorectal tumors; and, based on preliminary clinical data, may also have diagnostic utility as a biomarker for these cancers.

3 Jul 2010

WaferGen Biosystems to raise $7 million in registered direct offering

WaferGen Biosystems, Inc., a leading developer of state-of-the-art genomic analysis systems, today announced that it has received commitments from certain investors to purchase approximately $7 million of previously unissued securities in a registered direct offering. The investors include the Chairman and CEO, Alnoor Shivji, who has agreed to purchase $1 million of securities in the registered direct offering.

2 Jul 2010

Aushon BioSystems introduces new Human multiplex biomarker panels

Aushon BioSystems, Inc., a leading provider of advanced microarray instrumentation and laboratory services for biomarker discovery, development and analysis, has launched new Human multiplex biomarker panels for the quantification of eight biomarkers related to drug-induced kidney damage, or nephrotoxicity.

2 Jul 2010

Highly specific assay developed to detect ERG alterations in prostate cancer

Researchers at the Uniformed Services University of the Health Sciences Center for Prostate Disease Research, in collaboration with investigators at the Armed Forces Institute of Pathology and Walter Reed Army Medical Center, have developed a highly specific assay for the detection of ERG, a protein associated with tumor formations which is present in more than half of all prostate cancers.

1 Jul 2010

ResponseDX: Lung genetic test panel launched to detect EML4-ALK gene variants in lung cancer patients

Response Genetics Inc., a company focused on the development and sale of molecular diagnostic tests for cancer, today announced that it has expanded its ResponseDX: Lung genetic test panel to detect the presence of EML4-ALK gene variants in lung cancer patients. EML4-ALK fusion genes are present in about four percent of tumors from patients with non-small cell lung cancer.

1 Jul 2010

Molecular Biometrics' ViaMetrics-E procedure accurately predicts implantation rates in SET IVF cycles

Researchers from Molecular Biometrics, Inc. presented new data this week demonstrating that the company's ViaMetrics-E procedure more accurately predicts implantation rates in single embryo transfer (SET) cycles for patients undergoing infertility treatment. ViaMetrics-E is a rapid, non-invasive procedure used to enhance in vitro fertilization (IVF) outcomes by identifying viable embryos having the greatest reproductive potential.

30 Jun 2010

USPTO grants Vermillion Alzheimer's disease biomarker patent

Vermillion, Inc., a molecular diagnostics company, today announced that the United States Patent and Trademark Office (USPTO) has issued a notice of allowance of a patent entitled "Biomarkers for Alzheimer's disease" to the Company.

29 Jun 2010

New ISR's report highlights current and future adoption of biomarker technologies

Industry Standard Research (ISR) today announced the release of The State of Biomarkers in Drug Development report. 44 pharmaceutical and biotechnology professionals provided their strategies, insights, and predictions in this snapshot of a rapidly evolving market. In total, 37 significant pharma and biotech companies contributed to this endeavor.

29 Jun 2010

New database offers an efficient solution to locate and procure human tissue samples

An online service that positions itself as the "Craigslist of biospecimens" aims to eliminate one of the most costly bottlenecks in biomedical R&D - delays in obtaining specimens suitable for research.

29 Jun 2010

Aeterna Zentaris, Almac collaborate on study of AEZS-108 doxorubicin LHRH targeted conjugate compound

Aeterna Zentaris Inc., a late-stage drug development company specialized in oncology and endocrine therapy, today announced a collaborative study with Almac's Diagnostics division for the Company's doxorubicin luteinizing hormone-releasing hormone (LHRH) targeted conjugate compound, AEZS-108, aimed at determining LHRH receptor expression through the development of a companion diagnostic tool.

28 Jun 2010

Researchers discover genetic links to kidney failure, diabetic kidney disease

Researchers at the Translational Genomics Research Institute will make two presentations at this week's 70th Scientific Sessions of the American Diabetes Association, June 25-29, in Orlando, Florida.

28 Jun 2010

CorMedix announces dosing of first patient with CRMD-001 in Phase II clinical trial

CorMedix Inc., a pharmaceutical company focused on developing and commercializing therapeutic products for the prevention and treatment of Cardiorenal disease, today announced dosing of the first patient with CRMD-001 (a proprietary formulation of deferiprone) in a randomized, double-blind, placebo-controlled clinical trial.

25 Jun 2010

Biomarker News and Research

Further Reading

Biomagnetics, LANL collaborate to develop device for tuberculosis diagnosis

Optics Express publishes special focus issue on lung cancer imaging research

Aethlon Medical files provisional patent on behalf of ESI for exosome detection assay

MJFF announces $1.1M for projects to develop biomarker candidates for PD

CPRIT grants RBM $3 million Company Commercialization Award to expand OncologyMAP program

Adeona completes $1 million equity financing and provides update on Zinthionein ZC clinical study

Clusterin associated with development, severity and progression of Alzheimer's disease: Report

Metabolon unveils novel approach to identify patients at preterm delivery risk

Neogenix Oncology files patent application with USPTO for 16C3 antigen

WaferGen Biosystems to raise $7 million in registered direct offering

Aushon BioSystems introduces new Human multiplex biomarker panels

Highly specific assay developed to detect ERG alterations in prostate cancer

ResponseDX: Lung genetic test panel launched to detect EML4-ALK gene variants in lung cancer patients

Molecular Biometrics' ViaMetrics-E procedure accurately predicts implantation rates in SET IVF cycles

USPTO grants Vermillion Alzheimer's disease biomarker patent

New ISR's report highlights current and future adoption of biomarker technologies

New database offers an efficient solution to locate and procure human tissue samples

Aeterna Zentaris, Almac collaborate on study of AEZS-108 doxorubicin LHRH targeted conjugate compound

Researchers discover genetic links to kidney failure, diabetic kidney disease

CorMedix announces dosing of first patient with CRMD-001 in Phase II clinical trial

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