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Stanford study finds low risk of secondary blood cancers after CAR-T cell therapy

A large study by researchers at Stanford Medicine has found that the risk of secondary blood cancers after CAR-T cell therapy - a cell-based cancer treatment that exploded on the scene in 2017 as a treatment for intractable blood cancers - is low, despite a Food and Drug Administration warning.

12 Jun 2024

Synthetic cell mimics immune response via symmetry breaking

In a feat aimed at understanding how cells move and creating new ways to shuttle drugs through the body, scientists at Johns Hopkins Medicine say they have built a minimal synthetic cell that follows an external chemical cue and demonstrates a governing principle of biology called "symmetry breaking."

12 Jun 2024

Long-read RNA sequencing reveals novel insights into alternative splicing and disease genetics

Tokyo Medical and Dental University (TMDU) researchers harness long-read RNA sequencing to decode genetic intricacies and disease links.

12 Jun 2024

UC San Diego engineers develop algae-based microrobots for lung cancer treatment

Engineers at the University of California San Diego have developed microscopic robots, known as microrobots, capable of swimming through the lungs to deliver cancer-fighting medication directly to metastatic tumors.

12 Jun 2024

HiDEF-seq technique reveals the origins of DNA mutations in single strands

Mutations are changes in the molecular "letters" that make up the DNA code, the blueprint for all living cells. Some of these changes can have little effect, but others can lead to diseases, including cancer.

12 Jun 2024

Enhancing CAR-T cell therapy with biodegradable scaffolds

CAR-T cell therapies are transforming the treatment of previously incurable blood cancers. Six approved CAR-T products have been administered to more than 20,000 people, and more than 500 clinical trials are underway.

12 Jun 2024

First-in-human trial shows safety and efficacy of CAR T cell therapy for advanced prostate cancer

Treating prostate cancer with immunotherapy is currently difficult to do. But results from a first in-human phase 1 trial using a chimeric antigen receptor (CAR) T cell therapy developed by researchers from City of Hope, one of the largest cancer research and treatment organizations in the United States, showed that patients with advanced prostate cancer can be treated safely with the cellular immunotherapy with promising therapeutic activity, according to the phase 1 trial study published today in Nature Medicine.

12 Jun 2024

Human antibodies show promise against Black widow spider venom

There are various types of widow spiders, including black, red, and brown varieties in North and South America, the Australian redback spider, and several button spider species that inhabit South Africa.

12 Jun 2024

Instron® Launches Next Generation Autoinjector Testing System

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From Instron - USA 12 Jun 2024

Natural antioxidants could delay age-related decline in male testosterone production

Natural polyphenolic compounds to enhance testosterone production and prevent age-related hypogonadism in aging males.

12 Jun 2024

AI revolutionizes malaria diagnosis with 97.57% accuracy using EfficientNet

AI tool that uses deep learning to examine red blood cell images in blood smears for the timely detection of malaria.

12 Jun 2024

Gut bacteria turn dietary phytate into health-boosting fatty acids, study shows

Study reveals that human gut bacteria, particularly Mitsuokella jalaludinii, efficiently degrade dietary phytate into short-chain fatty acids, enhancing health benefits through microbial synergy.

12 Jun 2024

UD researchers pioneer universal, economical method for proteomics sample preparation

Proteins are workhorses that carry out most of the biological functions in our cells. While the genes we inherit from our parents, our so-called genome, are fixed and usually remain unchanged throughout our lives, proteins in our bodies are constantly changing, as we age, under different health conditions and upon stimulation, such as with medical treatment.

11 Jun 2024

H5N1 influenza outbreak in Texas dairy cattle sparks multi-species transmission concerns

Study identifies H5N1 influenza as the cause of an outbreak among dairy cattle in Texas, highlighting the risk of multi-species viral transmission and potential implications for human health.

11 Jun 2024

Researchers engineer water-soluble histidine kinase for enhanced antibiotic drug screens

A bacterial enzyme called histidine kinase is a promising target for new classes of antibiotics. However, it has been difficult to develop drugs that target this enzyme, because it is a "hydrophobic" protein that loses its structure once removed from its normal location in the cell membrane.

11 Jun 2024

Study reveals exploitation mechanism of virus-related nanoparticles for bacterial proliferation

Viruses are ubiquitous in the environment, and organisms have developed various mechanisms to counter their threat.

11 Jun 2024

Newcells Biotech strengthens executive and US team with key appointments

Dr Valeria Chichagova appointed as Director of Technology, Dr Colin Brown as Chief Scientific Officer, and Professor Lyle Armstrong as Scientific Advisor.

From Newcells Biotech 11 Jun 2024

Innovative blood test boosts accuracy of lung cancer screening

A blood-based, cell-free deoxyribonucleic acid (cfDNA) fragmentome assay for lung cancer detection.

11 Jun 2024

Wildfire smoke linked to over 52,000 premature deaths in California, study reveals

Research shows wildfire PM2.5 exposure caused over 52,000 premature deaths in California from 2008 to 2018, with significant economic impacts.

11 Jun 2024

Patient perspectives highlight urgent need for research on smell and taste disorders

Researchers and patient advocates from the Monell Chemical Senses Center, Smell and Taste Association of North America (STANA), and Thomas Jefferson University came together during the COVID-19 pandemic to incorporate patient voices in efforts to prioritize research areas focused on improving care for people with smell and taste disorders.

10 Jun 2024

B Cell News and Research

Stanford study finds low risk of secondary blood cancers after CAR-T cell therapy

Synthetic cell mimics immune response via symmetry breaking

Long-read RNA sequencing reveals novel insights into alternative splicing and disease genetics

UC San Diego engineers develop algae-based microrobots for lung cancer treatment

HiDEF-seq technique reveals the origins of DNA mutations in single strands

Enhancing CAR-T cell therapy with biodegradable scaffolds

First-in-human trial shows safety and efficacy of CAR T cell therapy for advanced prostate cancer

Human antibodies show promise against Black widow spider venom

Instron® Launches Next Generation Autoinjector Testing System

Natural antioxidants could delay age-related decline in male testosterone production

AI revolutionizes malaria diagnosis with 97.57% accuracy using EfficientNet

Gut bacteria turn dietary phytate into health-boosting fatty acids, study shows

UD researchers pioneer universal, economical method for proteomics sample preparation

H5N1 influenza outbreak in Texas dairy cattle sparks multi-species transmission concerns

Researchers engineer water-soluble histidine kinase for enhanced antibiotic drug screens

Study reveals exploitation mechanism of virus-related nanoparticles for bacterial proliferation

Newcells Biotech strengthens executive and US team with key appointments

Innovative blood test boosts accuracy of lung cancer screening

Wildfire smoke linked to over 52,000 premature deaths in California, study reveals

Patient perspectives highlight urgent need for research on smell and taste disorders

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

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