Preclinical News and Research

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Researchers working to develop non-invasive diagnostic technique for detecting Alzheimer's early

The ELEKIN research group of the UPV/EHU-University of the Basque Country is working to develop various non-invasive methodologies for the early detection of Alzheimer's disease.

18 Mar 2015

Pharmalink AB acquires anti-inflammatory drug candidate from Synartro AB

Pharmalink AB, a specialty pharma company, announces that it has acquired a novel product candidate in development for treating inflammation from Synartro AB. No financial details are disclosed.

18 Mar 2015

New drug-like molecule shows promise in preventing MS progression

Walter and Eliza Hall Institute scientists have developed a new drug-like molecule that can halt inflammation and has shown promise in preventing the progression of multiple sclerosis (MS).

17 Mar 2015

TSRI scientists confirm ribosome assembly as new target for anti-cancer drugs

Ribosomes, ancient molecular machines that produce proteins in cells, are required for cell growth in all organisms, accomplishing strikingly complex tasks with apparent ease. But defects in the assembly process and its regulation can lead to serious biological problems, including cancer.

17 Mar 2015

NantWorks, Sorrento collaborate to discover and develop novel anti-cancer immunotherapies

NantWorks, Inc. and Sorrento Therapeutics, Inc., announced today that they have entered into a binding agreement to initiate a global collaboration to discover and develop novel anti-cancer immunotherapies derived from Sorrento's proprietary G-MAB library against neoepitopes of tumor-specific antigens discovered using NantWorks' proprietary pan-omics based, precision medicine approach.

16 Mar 2015

New vaccine for post exposure treatment of rabies infection enters human clinical trial

Yisheng Biopharma Co., Ltd., a biopharmaceutical company focusing on the research, development, manufacturing, sales and marketing of vaccine products, announced that a new vaccine for the post exposure treatment of the rabies infection was entering human clinical trial after a six-year long collaboration with a number of research institutes worldwide.

16 Mar 2015

Creatine monohydrate disappoints in Parkinson’s disease

Creatine monohydrate fails to live up to its early promise in patients with Parkinson’s disease, show the results of the Long-term Study 1.

13 Mar 2015

BioSpecifics Technologies provides corporate update, reports Q4 and FY 2014 financial results

BioSpecifics Technologies Corp., a biopharmaceutical company developing first in class collagenase-based products marketed as XIAFLEX (collagenase clostridium histolyticum or CCH) in the U.S. and XIAPEX® in the EU, today announced its financial results for the fourth quarter and full year ended December 31, 2014 and provided a corporate update.

13 Mar 2015

Samsung Bioepis submits second biosimilar candidate MAA to EMA

Samsung Bioepis Co., Ltd., today announced that the Marketing Authorization Application (MAA) for SB2, its Remicade (Infliximab) biosimilar candidate, has been submitted to the European Medicines Agency (EMA).

13 Mar 2015

Vrije University Brussels installs MILabs PET-SPECT-CT-MRI platform for nanobody research

The comprehensive MILabs PET-SPECT-CT-MR preclinical platform combines the best PET-SPECT functional imaging capabilities (sub-half-mm SPECT resolution and sub-mm PET resolution) with high resolution anatomical imaging from an integrated X-ray CT subsystem and/or a compact cryogen free 1.5 T MRI unit

13 Mar 2015

'Turbocharged' protein holds promise in hemophilia gene therapy

Using gene therapy to produce a mutant human protein with unusually high blood-clotting power, scientists have successfully treated dogs with the bleeding disorder hemophilia, without triggering an unwanted immune response.

13 Mar 2015

Melbourne researchers develop new genome editing technology to kill blood cancer cells

Melbourne researchers have developed a new genome editing technology that can target and kill blood cancer cells with high accuracy.

12 Mar 2015

Existing epilepsy drug reverses aMCI in elderly patients at risk for Alzheimer's disease

A novel therapeutic approach for an existing drug reverses a condition in elderly patients who are at high risk for dementia due to Alzheimer's disease, researchers at Johns Hopkins University found.

12 Mar 2015

Ablative Solutions named recipient of CRT's Top Cardiovascular Innovation Award

Ablative Solutions, Inc., a venture-backed, privately-held clinical stage company headquartered in Kalamazoo, MI, with offices in Menlo Park, CA, announced today that it was the recipient of a "Top Cardiovascular Innovation Award" from Cardiovascular Research Technologies for the Peregrine System.

12 Mar 2015

Glucocorticoid therapies promote functional recovery of blood-brain barrier after blast injury

Barclay Morrison III, associate professor of biomedical engineering at Columbia Engineering, has led the first study to determine underlying biological mechanisms that promote functional recovery of the blood-brain barrier (BBB) after blast injury. The research demonstrates that treatment with the glucocorticoid, dexamethasone, after primary blast injury promotes rapid recovery of an in vitro model of the BBB, a highly restrictive semi-permeable barrier whose primary function is to maintain the brain's microenvironment and protect it from potentially toxic substances.

12 Mar 2015

InMed, University of Debrecen partner to develop novel therapies to treat ocular allergies

InMed Pharmaceuticals Inc. announces it has formed an exclusive strategic collaboration with the University of Debrecen, Hungary, to develop novel phytocannabinoid-based therapies to treat ocular allergic symptoms.

10 Mar 2015

NMR screening solution specifically for the analysis of honey launched by Bruker

This new NMR screening solution specifically for the analysis of honey is the most recent module of Bruker’s well-established FoodScreener™ product line to be released in April.

From Bruker 10 Mar 2015

Wine-Profiling solution based on NMR introduced by Bruker

This substantially enhanced second-generation module of the FoodScreener™ for wine profiling allows easy and cost-efficient NMR-based wine analysis, now for the first time also for key regions in France, Italy and Spain. In addition to geographical origin, NMR Wine Profiling can determine further key authenticity parameters such as grape variety, vintage year and possible water addition. This comprehensive solution offers a quick, fully automated and cost-efficient tool to ensure wine quality and authenticity, protecting brand integrity and consumer confidence.

From Bruker 10 Mar 2015

Phico Therapeutics gets £2.25M Translation Award to develop SASPject PT4 antibiotic for E. coli, K. pneumoniae

Phico Therapeutics, a biotechnology company developing a novel platform technology for a new generation of antibiotics aimed at overcoming antibacterial resistance, has been awarded a £2.25M Translation Award by the Wellcome Trust to develop its SASPject PT4 antibiotic, aimed at Escherichia coli and Klebsiella pneumoniae.

9 Mar 2015

Oxytocin nasal spray helps healthy men reduce consumption of fatty foods

A synthetic nasal formulation of the hormone oxytocin reduced caloric intake in healthy men, particularly consumption of fatty foods, after a single treatment, a new study finds. The results, to be presented Sunday at The Endocrine Society's 97th annual meeting in San Diego, confirm those of animal studies showing oxytocin reduces food intake.

6 Mar 2015

Preclinical News and Research

Researchers working to develop non-invasive diagnostic technique for detecting Alzheimer's early

Pharmalink AB acquires anti-inflammatory drug candidate from Synartro AB

New drug-like molecule shows promise in preventing MS progression

TSRI scientists confirm ribosome assembly as new target for anti-cancer drugs

NantWorks, Sorrento collaborate to discover and develop novel anti-cancer immunotherapies

New vaccine for post exposure treatment of rabies infection enters human clinical trial

Creatine monohydrate disappoints in Parkinson’s disease

BioSpecifics Technologies provides corporate update, reports Q4 and FY 2014 financial results

Samsung Bioepis submits second biosimilar candidate MAA to EMA

Vrije University Brussels installs MILabs PET-SPECT-CT-MRI platform for nanobody research

'Turbocharged' protein holds promise in hemophilia gene therapy

Melbourne researchers develop new genome editing technology to kill blood cancer cells

Existing epilepsy drug reverses aMCI in elderly patients at risk for Alzheimer's disease

Ablative Solutions named recipient of CRT's Top Cardiovascular Innovation Award

Glucocorticoid therapies promote functional recovery of blood-brain barrier after blast injury

InMed, University of Debrecen partner to develop novel therapies to treat ocular allergies

NMR screening solution specifically for the analysis of honey launched by Bruker

Wine-Profiling solution based on NMR introduced by Bruker

Phico Therapeutics gets £2.25M Translation Award to develop SASPject PT4 antibiotic for E. coli, K. pneumoniae

Oxytocin nasal spray helps healthy men reduce consumption of fatty foods

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