Therapy News and Research

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Scientists discover breakthrough method to treat neuronal diseases

What do stroke, epilepsy, head or spinal cord trauma, Parkinson’s disease and Alzheimer’s disease patients have in common? They all suffer from neuronal cell death brought about by the absence or malfunction of specific genes.

30 Aug 2004

Surgery for angina in the elderly provides long-term mortality

Elderly people who undergo surgery or angioplasty to treat chest pain fare just as well long-term as those treated with medication, researchers report in Circulation: Journal of the American Heart Association.

30 Aug 2004

Early use of aggressive statin therapy may offer some benefit for coronary patients

Statins initiated early after a patient experiences an acute coronary syndrome (ACS) event at dosages above the typical starting dose may help reduce subsequent cardiovascular events, but the high dose regimen used may increase the risk for muscle-related complications, according to the results from the Phase Z portion of the A to Z Trial released on the JAMA website today.

30 Aug 2004

Does estrogen help perception, intuition or reasoning?

Now, a new study at the University of Illinois at Urbana-Champaign suggests that the stress of any given task at least partially determines if hormones will help the mind.

29 Aug 2004

New guidelines today to diagnose and treat acromegaly

The American Association of Clinical Endocrinologists (AACE) released new guidelines today to diagnose and treat acromegaly, a rare and debilitating endocrine disorder. The guidelines are published in the May/June 2004 issue of AACE's peer-reviewed journal Endocrine Practice.

29 Aug 2004

No benefit from early PCI/CABG in high risk unstable angina patients

Patients with chest pain are recognized as being at high risk of subsequent adverse cardiac events when their plasma levels of cardiac troponin are elevated as evidence of myocardial damage.

29 Aug 2004

Atrial fibrillation patients often receive needless treatment

Results of the Euro Heart Survey on atrial fibrillation (AF), demonstrate that many AF patients receive clot-preventing drugs while not at risk for stroke.

29 Aug 2004

Solid evidence that best treatment for multiple sclerosis is pregnancy

For years, doctors have suggested the best treatment for multiple sclerosis is pregnancy. Now, an Oregon study is delivering solid evidence to support the theory.

27 Aug 2004

Statins (HMG-CoA reductase inhibitors), are effective long term

Statins (HMG-CoA reductase inhibitors), a class of drugs that block production of cholesterol in the liver, lower total cholesterol and LDL and are also associated with cardiovascular benefits, are effective in the long term, conclude authors of a study in this week’s issue of THE LANCET.

26 Aug 2004

Success of breast screening varies between women

Breast cancer may be harder to detect and exclude among women with certain personal and lifestyle characteristics, according to research published in this week's BMJ.

26 Aug 2004

Study of new gene and cell therapy to better understand how genetically-engineered cells can help pace the heart

Guidant Corporation, Columbia University and Stony Brook University will collaborate to study a new gene and cell therapy that may ultimately provide better understanding of how genetically-engineered cells can help pace the heart.

26 Aug 2004

FDA reinforces use of Sustiva in first-line HIV combination therapy

Bristol-Myers Squibb has announced that Sustiva® (efavirenz) has received approval from the U.S. Food and Drug Administration to include new long-term virologic and clinical data from BMS Study 006 in its prescribing information.

26 Aug 2004

Botox may help improve movement in children suffering from cerebral palsy

A product that has made headlines for its use in enhancing beauty for the “not-so-young” may help improve movement in children suffering from cerebral palsy according to a University of Auckland PhD student.

26 Aug 2004

Are nicotine patches safe for pregnant women?

A £1 million study, being led by a team of multidisciplinary researchers at The University of Nottingham, is to look at whether nicotine replacement skin patches could help pregnant mums to stop smoking.

26 Aug 2004

Prozac helps treat adolescents with depression

The TADS researchers said that major depressive disorder is common, with one in 20 teens affected at varying levels of severity. Like other forms of depression, major depressive disorder has been associated with increased risk of suicidal behavior and with completed suicide.

26 Aug 2004

Phase 1 clinical trial of new anticancer drug from Human Genome Sciences

Human Genome Sciences has begun dosing patients in a Phase 1 clinical trial of HGS-TR2J, a novel agonistic human monoclonal antibody to TRAIL Receptor 2, in patients with advanced solid malignancies.

25 Aug 2004

Early cholesterol-lowering drug therapy reduces artery-clogging plaque

Early cholesterol-lowering drug therapy after hospitalization for acute coronary syndrome appears to reduce artery-clogging plaque, according to a study reported in Circulation: Journal of the American Heart Association.

25 Aug 2004

Scientists have discovered a protein that could be the key to finding a cure for asthma

Scientists at the University's Department of Pharmacology and the Woolcock Institute of Medical Research have discovered a protein produced in human lung cells that could be the key to finding a cure for asthma.

25 Aug 2004

Researchers have identified multiple changes in the gene-expression patterns of cells involved with tumor progression in liver cancer patients

Virginia Commonwealth University researchers have identified multiple changes in the gene-expression patterns of cells involved with tumor progression in liver cancer patients and in those with cirrhosis, which may help scientists predict a person’s risk of developing primary liver cancer.

25 Aug 2004

Gray matter in brain associated with language processing among people with a family history of dyslexia

Italian researchers have observed significant reductions of gray matter volume in areas of the brain associated with language processing among people with a family history of dyslexia in comparison with controls with no reading problems.

24 Aug 2004