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Study reports promising novel approach to treat therapy resistant pediatric brain tumors

Researchers used an experimental molecular therapy in preclinical laboratory tests to effectively treat several types of deadly pediatric brain cancer and now propose advancing the treatment to clinical testing in children.

17 Apr 2018

Sleep restriction therapy does not interfere with insomnia patient’s driving ability, research shows

The use of Sleep Restriction Therapy to help treat adults with insomnia is under-recognized – despite encouraging results since it was first introduced in the late 1980s.

17 Apr 2018

Versatile mouse model opens doors to new targeted cancer therapies

Researchers from the Seve Ballesteros Foundation-CNIO Brain Tumour Group at the Spanish National Cancer Research Centre have developed an extremely powerful and versatile mouse model that will improve cancer research and accelerate pre-clinical testing of novel targeted therapies. Their work appears in Nature Communications.

13 Apr 2018

Scientists developing new vaccines against heroin and prescription opioids

Heroin and prescription opioid abuse and fatal overdoses are a public health emergency in the United States. Vaccines offer a potential new strategy to treat opioid abuse and prevent fatal opioid overdoses.

12 Apr 2018

New class of drug holds potential to help patients with treatment-resistant cancers

Researchers have discovered a new class of drug that has the potential to help cancer patients who no longer respond to existing therapies.

10 Apr 2018

New $3.2 million grant funds research to advance promising malaria vaccine

The Global Health Innovative Technology Fund has awarded the University of Florida and partners in the United States and Japan $3.2 million to advance a promising vaccine to prevent transmission of malaria.

29 Mar 2018

New computer program provides more thorough preparation for diagnosis of lung diseases

Three-dimensional visualization based on computer tomography imaging provides more thorough preparation for the diagnosis of lung diseases.

5 Mar 2018

NIAID details new strategic plan for creating safe, effective universal influenza vaccine

Developing a universal influenza vaccine -- a vaccine that can provide durable protection for all age groups against multiple influenza strains, including those that might cause a pandemic -- is a priority for the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health.

28 Feb 2018

Home-based semen analysis kit could provide rapid, cost-effective way to test male fertility

It is estimated that of the 70 million cases of infertility worldwide, almost half are caused by factors relating to the male partner. A number of semen parameters – motility, morphology, velocity, volume, concentration, and count – affect male fertility.

28 Feb 2018

Researchers identify promising new drug target for Ewing sarcoma

Screening a class of recently-developed drug compounds -- so-called "CDK inhibitors" capable of blocking CDK7/12/13 proteins -- against hundreds of different human cancer cell lines, researchers at Dana-Farber/Boston Children's Cancer and Blood Disorders Center have found that CDK12 inhibitors pack a particularly lethal punch to Ewing sarcoma, a rare cancer typically affecting children and young adults.

25 Jan 2018

Researchers find new way to halt growth of breast cancer cells

An international team of researchers led from Karolinska Institutet and Science for Life Laboratory in Sweden have found a new way of halting the growth of breast cancer cells.

18 Jan 2018

UAB study shows missense mutations as key risk factor for severe symptoms of neurofibromatosis type 1

Research led by Ludwine Messiaen, Ph.D., professor of genetics at the University of Alabama at Birmingham, shows that missense mutations in a cluster of just five codons in the NF1 gene are an important risk factor for severe symptoms of the genetic disease neurofibromatosis type 1.

28 Dec 2017

Hidden genes hold blueprints for designing new anti-cancer drugs

New research suggests these hidden genes hold the blueprints for designing new, even more effective cancer-targeting compounds.

12 Dec 2017

Investigational ZPIV vaccine found to be safe and immunogenic in trial participants

The investigational Zika purified inactivated virus (ZPIV) vaccine was well-tolerated and induced an immune response in participants, according to initial results from three Phase 1 clinical trials.

5 Dec 2017

Elevated levels of chronic stress hormones may promote EGFR inhibitor resistance in NSCLC patients

Elevated levels of chronic stress hormones, such as those produced by psychological distress, may promote resistance to drugs commonly used to treat lung cancer patients with EGFR mutations, according to new research from The University of Texas MD Anderson Cancer Center.

9 Nov 2017

Study characterizes hypertensive population with excess weight or obesity and sedentary habits

For the last seven years, researchers in the UPV/EHU's Department of Physical and Sports Education have been studying the hypertensive population with excess weight/obesity and sedentary habits. In a recent publication, this group has determined the state of health of this population through various key physical, physiological, clinical and nutritional markers and has separated them by sex and physical condition.

28 Oct 2017

Study could pave way for more effective cancer therapies

Many tumors possess mechanisms to avoid destruction by the immune system. For instance, they misuse the natural "brakes" in the immune defense mechanism, which normally prevent an excessive immune response. Researchers at the University of Bonn have now been able to take off one of these brakes.

17 Oct 2017

New study uncovers 13 previously-unknown genetic risk variants for restless legs syndrome

A new study into the genetics underlying restless legs syndrome has identified 13 previously-unknown genetic risk variants, while helping inform potential new treatment options for the condition.

13 Oct 2017

Highly elastic surgical glue quickly seals wounds without need for staples or sutures

A highly elastic and adhesive surgical glue that quickly seals wounds without the need for common staples or sutures could transform how surgeries are performed.

4 Oct 2017

Rapid, sensitive genetic test successfully detects some aggressive types of pancreatic cancer

A genetic test developed at UPMC proved highly sensitive at determining which pancreatic cysts are most likely to be associated with one of the most aggressive types of pancreatic cancer, UPMC and University of Pittsburgh School of Medicine scientists reported in Gut, the journal of the British Society of Gastroenterology.

3 Oct 2017