Histology News and Research

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Sectioning of bone as a specialist histology specimen

The significance of histological examination in the classification and diagnosis of clinical conditions is reliant on the expertise of the histology laboratory in managing the wide spectrum of specimen types submitted for analysis.

From Thermo Fisher Scientific Inc. 9 Jul 2012

Routine use of pelvic CT scans in Wilms tumor questioned

Omitting pelvic computed tomography scans from the routine surveillance of off-therapy patients with Wilms tumor could reduce radiation exposure without compromising relapse detection rates, researchers report.

2 Jul 2012

Natural language processing programs can help measure colonoscopy quality

A new study shows that natural language processing programs can "read" dictated reports and provide information to allow measurement of colonoscopy quality in an inexpensive, automated and efficient manner.

23 Jun 2012

Aeterna Zentaris announces perifosine Phase 1 trial on neuroblastoma

Aeterna Zentaris Inc. today announced that Phase 1 trial results for its oral PI3K/Akt inhibitor, perifosine, showed the drug's activity against chemo-resistant and radio-resistant neuroblastoma, while allowing good quality of life and sparing vital organs. Neuroblastoma is a type of childhood cancer which usually begins in nerve tissues.

22 Jun 2012

Lilly announces final results from ALIMTA Phase III study on NSCLC

Final results from PARAMOUNT, a Phase III study of ALIMTA (pemetrexed for injection) in the continuation maintenance setting, demonstrated improved overall survival in patients with advanced nonsquamous non-small cell lung cancer (NSCLC) treated with ALIMTA continuation maintenance, according to data announced today by Eli Lilly and Company.

5 Jun 2012

‘Virtually’ no ulcer bleeding after H. pylori eradication

Rebleeding is rare in patients with complicated peptic ulcers after successful treatment for Helicobacter pylori infection, Spanish clinicians report.

31 May 2012

Lung in Oncology models for drug discovery launched by PRECOS

Preclinical Oncology Services Limited (PRECOS), a leading pre-clinical research and development service provider with a specific focus on oncology, has launched its Lung In ONcology model atlas (LION).

29 May 2012

Heart-wall muscle fibers are locally arranged in a special ‘minimal surface’

A study led by researchers from McGill University provides new insights into the structure of muscle tissue in the heart - a finding that promises to contribute to the study of heart diseases and to the engineering of artificial heart tissue.

29 May 2012

Cook Medical adds 25 gage needle to line of FNB histology portfolio

Cook Medical has added a 25 gage needle to its EchoTip ProCore line of fine needle biopsy (FNB) histology needles, which are designed for use in a procedure known as endoscopic ultrasound, or EUS. The EchoTip ProCore is a single-use, disposable needle for FNB intended for sampling of submucosal lesions, mediastinal masses, lymph nodes and intraperitoneal masses.

21 May 2012

Mount Sinai cancer researchers to present several landmark studies at ASCO meeting

Mount Sinai School of Medicine researchers will present several landmark studies, including data on treatment trends in late-stage cancer, a promising multiple myeloma vaccine, and predictive models of soft tissue sarcomas, prostate and bladder cancer, at the 2012 American Society of Clinical Oncology (ASCO) meeting June 1-5, 2012 in Chicago.

19 May 2012

Math models can be useful tools for study of cancer progression

Using mathematical models, researchers in the Integrated Mathematical Oncology (IMO) program at Moffitt Cancer Center are focusing their research on the interaction between the tumor and its microenvironment and the "selective forces" in that microenvironment that play a role in the growth and evolution of cancer.

3 May 2012

Kras gene triggers metabolic changes that fuel cancer cells

Researchers at Dana-Farber Cancer Institute have shown that advanced pancreatic cancers in mice can't survive without continued expression of a mutant oncogene that "rewires" key metabolic pathways to fuel the cancer cells.

27 Apr 2012

Combination treatment shows promise against NSCLC patients ineligible for bevacizumab

A combination of nab-paclitaxel and carboplatin for the treatment of non-small cell lung cancer may be a promising option for patients ineligible for treatment with bevacizumab, according to data presented at the AACR Annual Meeting 2012, held here March 31 - April 4.

4 Apr 2012

Cell graphs link structure of human tissue to corresponding biological function

Computer scientists and biologists in the Data Science Research Center at Rensselaer Polytechnic Institute have developed a rare collaboration between the two very different fields to pick apart a fundamental roadblock to progress in modern medicine. Their unique partnership has uncovered a new computational model called "cell graphs" that links the structure of human tissue to its corresponding biological function.

3 Apr 2012

Imatinib improves RFS, overall survival in GIST patients after surgery

Among patients with a high risk of recurrence of a gastrointestinal stromal tumor following surgery for its removal, patients who received imatinib (a drug to treat certain cancers) for 3 years instead of 1 had improved recurrence-free survival and overall survival, according to a study in the March 28 issue of JAMA.

28 Mar 2012

Simple genetic test could help predict aggressiveness of rhabdomyosarcoma tumours

A study led by Dr Janet Shipley from The Institute of Cancer Research (ICR) in London in collaboration with Dr Mauro Delorenzi from the SIB Swiss Institute of Bioinformatics in Lausanne has shown that a simple genetic test could help predict the aggressiveness of rhabdomyosarcoma tumours in children

28 Mar 2012

Ventana launches novel platform for special stains

Ventana Medical Systems, Inc., a member of the Roche Group, is now introducing a novel platform for special stains, built on its industry-leading VENTANA BenchMark technology.

19 Mar 2012

DBS introduces novel Multiplex Immunohistochemistry cancer kits

Diagnostic Biosystems, a specialty Immunohistochemistry company, announces its debut as an automated IHC company, introducing the Mosaic 360 System with a product offering of novel Multiplex Immunohistochemistry kits and a complementary line of optimized IHC reagents.

19 Mar 2012

F-DOPA PET/CT imaging alters management plans for patients with brain cancer

Imaging amino acid transporters with positron emission tomography/computed tomography (PET/CT) has been shown to significantly alter intended management plans for patients with brain tumors, according to research in the March issue of The Journal of Nuclear Medicine.

2 Mar 2012

Biocompatible interface scaffolds for improved prosthetics

Sandia National Laboratories researchers, using off-the-shelf equipment in a chemistry lab, have been working on ways to improve amputees' control over prosthetics with direct help from their own nervous systems.

22 Feb 2012