Hormones News and Research

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Scientists decode ovarian aging with groundbreaking molecular atlas

Researchers unveil a comprehensive multi-omics atlas of ovarian aging, highlighting coordinated gene expression changes, mTOR signaling, and cellular communication as key to understanding fertility decline.

26 Nov 2024

Tirzepatide cuts diabetes risk by 90% in obese patients, study shows

Tirzepatide, a new injectable weight-loss drug with the trade name Zepbound, reduced the risk of diabetes in patients with obesity and prediabetes by more than 90% over a three-year period, compared with placebo, according to the results of a new study led by investigators at Weill Cornell Medicine, NewYork-Presbyterian, Yale School of Medicine and other institutions.

26 Nov 2024

Atlas maps plasma proteins to transform disease diagnosis and treatment

Researchers have developed the most comprehensive atlas linking plasma proteins to diseases and traits in over 53,000 individuals, offering groundbreaking insights for precision medicine. This resource uncovers 168,100 protein-disease associations and identifies new therapeutic targets.

25 Nov 2024

New insights into leptin's role in hypothalamic neural circuit development

Researchers from the Vanderbilt University School of Medicine Basic Sciences have uncovered the first example of activity-dependent development of hypothalamic neural circuitry.

25 Nov 2024

How neural and hormonal gut-brain communication shapes metabolism and health

Interoception research reveals how gut-brain communication via neural, hormonal, and microbial pathways regulates metabolism, hunger, and overall health, offering insights for therapeutic innovations.

25 Nov 2024

Probiotics shown to mitigate effects of toxic fire-retardant chemicals

Polybrominated diphenyl ethers, or PBDEs, are fire-retardant chemicals that are found everywhere - upholstery, carpets, curtains, electronics, and even infant products.

23 Nov 2024

CU Boulder study sheds light on sex differences in sleep patterns

Females sleep less, wake up more often and get less restorative sleep than males, according to a new animal study by CU Boulder researchers.

21 Nov 2024

Saliva microbes differ in pregnant women with stress and mental health symptoms

Research links oral cavity microbes to maternal mental health, revealing potential interventions during pregnancy to enhance psychological well-being.

21 Nov 2024

Jaw muscle size linked to sarcopenia risk in older adults

As populations age, the prevalence of sarcopenia - a progressive loss of muscle mass and function - has become an increasingly urgent public health concern. Sarcopenia increases the risk of falls and frailty, reduces the quality of life for older adults, and heightens the likelihood of requiring long-term care. Preventing sarcopenia is, therefore, crucial for alleviating this healthcare burden.

20 Nov 2024

Timing of meals impacts glucose tolerance and health

Although people have always said that having a light and early dinner is better, a study by the Universitat Oberta de Catalunya (UOC) and Columbia University has provided the scientific grounds for this argument.

20 Nov 2024

Hypertension drug may reduce heart failure risk in people recovering from heart attack

New research found that the medication spironolactone, often prescribed for hypertension (high blood pressure), may reduce the risk of heart failure in people recovering from a heart attack.

18 Nov 2024

Hormone therapy and puberty blockers alter skeletal size in transgender individuals

Skeletal size may be altered by gender-affirming hormone therapy only if puberty has also been suppressed during adolescence, according to research presented at the 62nd Annual European Society for Paediatric Endocrinology Meeting in Liverpool.

18 Nov 2024

Growth hormone-releasing hormone transforms therapeutic potential in health and chronic disease

Researchers review the biological activities of growth hormone-releasing hormone and its analogs.

17 Nov 2024

Study reveals high-resolution structure of blood pressure-regulating receptor

Weill Cornell Medicine researchers have determined the full-length structure of a blood pressure-regulating hormone receptor for the first time, uncovering how it functions, which may enable better drug targeting of the receptor for diseases like hypertension and heart failure.

15 Nov 2024

Study highlights air pollution as key environmental factor in autism risk

Air pollution is a key environmental risk factor for autism, influencing neurodevelopment through neuroinflammation, oxidative stress, and epigenetic changes.

14 Nov 2024

Getting enough sleep linked to lower hypertension risk in teens

Adolescents who meet the recommended guidelines of nine to 11 hours of sleep per day were shown to have a significantly lower risk of hypertension, according to a new study from UTHealth Houston.

11 Nov 2024

How gut bacteria regulate stress and sleep cycles

This study reveals that gut microbiota, particularly Lactobacillus species, regulate the daily rhythm of stress hormones like corticosterone, influencing stress responses and brain function at different times of the day. Disruptions in gut bacteria lead to altered stress responses and increased susceptibility to disorders like depression.

10 Nov 2024

Rice bioengineers uncover why IL-12 immunotherapy loses effectiveness

A team of Rice University bioengineers has developed a mathematical model that clarifies why interleukin-12 (IL-12) ⎯ a potent immune-boosting protein that holds promise for cancer treatment ⎯ loses effectiveness over time when used as an immunotherapeutic.

6 Nov 2024

Study uncovers key role of gut microbiota in regulating stress responses

A pioneering study has uncovered the vital role that gut microbiota plays in regulating stress responses by interacting with the body's circadian rhythms.

5 Nov 2024

Babies born to mothers with PCOS and obesity are smaller in size

Women with polycystic ovary syndrome (PCOS) and obesity are at a higher risk of giving birth to smaller babies in terms of birth weight, length, and head circumference, according to a recent study conducted at the Norwegian University of Science and Technology (NTNU).

5 Nov 2024