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Regularly sharing experiences enhances hospital and hospice staff's wellbeing

Healthcare staff who regularly share the emotional, social or ethical challenges they face in the workplace experience less psychological distress, improved teamwork and increased empathy and compassion for patients and colleagues, a new study commissioned by the National Institute for Health Research reports.

31 Oct 2017

Seeking a peaceful death amid the flames

Even when fire threatened her home in downtown Sonoma, the elderly woman inside who was suffering from late-stage cancer refused to leave.

27 Oct 2017

Penn researchers awarded $3.75 million grant to investigate how meal timings affect human health

Disrupting sleep-wake cycles from a predominantly daytime to a delayed eating lifestyle, -- i.e., skipping breakfast and making lunch the first meal of the day, plus eating late dinner, disrupts the body's natural circadian (24-hour) rhythm, the cycle that tells us when to sleep, wake up, eat, and influences hormones and other functions.

26 Oct 2017

Penn study sheds light on genetic cause of early hearing loss

From the moment a baby is born, they are put through a battery of screenings to test for all sorts of characteristics, which includes the sense of hearing.

26 Oct 2017

Penn researchers provide new insights into how Notch drives growth of B-cell cancers

Notch is one of the most frequently mutated genes in chronic lymphocytic leukemia (CLL), the most common leukemia in adults in the United States. It is also often mutated in other common B cell tumors, such as mantle cell lymphoma.

23 Oct 2017

Proton beam therapy has lower rates of toxicity in pediatric patients with head and neck cancer

Pediatric patients with head and neck cancer can be treated with proton beam therapy (PBT) instead of traditional photon radiation, and it will result in similar outcomes with less impact on quality of life.

23 Oct 2017

Amid for-profit surge, rural hospice has offered free care for 40 years

Rose Crumb can't even count the number of people she's helped die. The former nurse, 91, who retired in her mid-80s, considers the question and then shakes her head, her blue eyes sharp above oval spectacles.

20 Oct 2017

New CAR-T cell therapy offers effective option for certain blood cancer patients

Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine in St. Louis is one of the first centers nationwide to offer a new immunotherapy that targets certain blood cancers.

19 Oct 2017

Penn researchers functionally dissect gene variant linked to FTLD

Seven years ago, Penn Medicine researchers showed that mutations in the TMEM106B gene significantly increased a person's risk of frontotemporal lobar degeneration (FTLD), the second most common cause of dementia in those under 65.

19 Oct 2017

Researchers examine how palliative care impacts heart failure patients

Patients living with heart failure receive palliative care significantly less often than patients with other illnesses, including cancer, despite evidence that such care improves symptom management and quality of life.

18 Oct 2017

Specific regions of silenced DNA help define cell's identity, study suggests

The fundamental mechanisms governing how cells form an identity such as becoming a muscle cell or a nerve cell are not fully understood. Multiple diseases, including cancer, have been linked to cells going down the wrong developmental path during maturation.

13 Oct 2017

Study pinpoints racial disparities linked to severity and effects of peripartum cardiomyopathy

African American women were found to be twice as likely to be diagnosed with peripartum cardiomyopathy as compared to women of Caucasian, Hispanic/Latina, Asian, and other ethnic backgrounds, according to a new study--the largest of its kind--published today in JAMA Cardiology by researchers from the Perelman school of Medicine at the University of Pennsylvania.

11 Oct 2017

Study reveals unique norovirus characteristic of hiding from host immune system

Noroviruses are the leading cause of non-bacterial gastroenteritis in the world and are estimated to cause 267 million infections and 20,000 deaths each year. This virus causes severe diarrhea, nausea, and stomach pain.

11 Oct 2017

Penn’s ITMAT 12th Annual International Symposium focuses on pain biology, aging, and brain disorders

The latest science in why pain afflicts people differently, precision medicine and brain disorders, and how the bat genome informs the study of human aging, among many other topics, will be covered at the University of Pennsylvania's Institute for Translational Medicine and Therapeutics' 12th Annual International Symposium.

9 Oct 2017

Penn Medicine professor receives New Innovator Award from NIH

Hao Wu, PhD, an assistant professor of Genetics in the Perelman School of Medicine at the University of Pennsylvania has received a New Innovator Award from the National Institutes of Health. These awards provide each recipient $1.5 million over five years to pursue high-risk, high-reward investigations that could have implications for human health.

9 Oct 2017

Analysis of survey data finds no significant racial differences in quality of end-of-life care

An analysis of survey data found no significant racial differences in various aspects of the quality of end-of-life care, although survey respondents reported deficiencies in the quality of end-of-life care for both black and white patients who died, including unmet symptom needs, problems with communication and less than optimal decision-making, according to an article published by JAMA Internal Medicine.

9 Oct 2017

New DNA-based Zika vaccine demonstrates safety and ability to elicit immune response

A new generation DNA-based Zika vaccine is the first to demonstrate both safety and the ability to elicit an immune response against Zika in humans, according to new research from the Perelman School of Medicine at the University of Pennsylvania, conducted in partnership with The Wistar Institute, Inovio Pharmaceuticals, and GeneOne Life Science, Inc.

5 Oct 2017

Study on cell stress response may hold promise for treating inflammation-related disorders

Stress – defined broadly – can have a profoundly deleterious effect on the human body. Even individual cells have their own way of dealing with environmental strains such as ultraviolet radiation from the sun or germs.

4 Oct 2017

Penn researchers develop predictive model to help lung cancer patients avoid ED visits

A pilot program that uses big data to predict which lung cancer patients will require a trip to an emergency department successfully anticipated a third of all ED visits over a two-week trial period, and was further able to identify which patients were at high risk and low risk of requiring such care.

27 Sep 2017

Penn study finds sustained use of activity trackers for at least 6 months among 80% of users

Use of activity trackers, such as wearable devices and smartphone apps, is on the rise, and a new study shows that 80 percent of users stuck with the device for at least six months.

27 Sep 2017

Hospice News and Research

Regularly sharing experiences enhances hospital and hospice staff's wellbeing

Seeking a peaceful death amid the flames

Penn researchers awarded $3.75 million grant to investigate how meal timings affect human health

Penn study sheds light on genetic cause of early hearing loss

Penn researchers provide new insights into how Notch drives growth of B-cell cancers

Proton beam therapy has lower rates of toxicity in pediatric patients with head and neck cancer

Amid for-profit surge, rural hospice has offered free care for 40 years

New CAR-T cell therapy offers effective option for certain blood cancer patients

Penn researchers functionally dissect gene variant linked to FTLD

Researchers examine how palliative care impacts heart failure patients

Specific regions of silenced DNA help define cell's identity, study suggests

Study pinpoints racial disparities linked to severity and effects of peripartum cardiomyopathy

Study reveals unique norovirus characteristic of hiding from host immune system

Penn’s ITMAT 12th Annual International Symposium focuses on pain biology, aging, and brain disorders

Penn Medicine professor receives New Innovator Award from NIH

Analysis of survey data finds no significant racial differences in quality of end-of-life care

New DNA-based Zika vaccine demonstrates safety and ability to elicit immune response

Study on cell stress response may hold promise for treating inflammation-related disorders

Penn researchers develop predictive model to help lung cancer patients avoid ED visits

Penn study finds sustained use of activity trackers for at least 6 months among 80% of users

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