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New insight into SARS-CoV-2 nsp14 protein opens door to new drugs

In a recent research paper currently available on bioRxiv* preprint server, scientists from the University of Oxford in the United Kingdom and the University of Auckland in New Zealand identified several structural specificities of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that may serve as viable starting points for the development and optimization of viral inhibitors against coronavirus disease 2019 (COVID-19) and other future threats.

16 Mar 2022

Detailed molecular map of stratum corneum can help develop new skin treatments

Scientists have accurately analyzed the tough barrier layer of the skin giving the most detailed molecular map of its structure that will help in the development of new skin products and treatments.

14 Mar 2022

Irradiation of tumors with laser protons tested for the first time

Irradiation with fast protons is a more effective and less invasive cancer treatment than X-rays. However, modern proton therapy requires large particle accelerators, which has experts investigating alternative accelerator concepts, such as laser systems to accelerate protons.

14 Mar 2022

Malaria drug could help treat chemotherapy-resistant head and neck cancers

A new study suggests that the malaria drug hydroxychloroquine inhibits pathways that drive resistance to the chemotherapy agent cisplatin in head and neck cancers and restores tumor-killing effects of cisplatin in animal models.

14 Mar 2022

Study may provide insight into the evolution of D-amino acid function in marine invertebrates

Amino acids are the basic building blocks of living organisms and typically occur in a configuration known as the L-form. However, there are a few exceptional examples of the structural mirror image of the L-form (known as the D-form) being present in animals.

11 Mar 2022

Merck and Waters to Collaborate on Extractables and Leachables Reference Library

Merck, a leading science and technology company, today announced that its Life Science business sector has entered into a collaboration with Waters Corporation to build and expand an Extractables and Leachables (E&L) Reference Library to include ion mobility measurements.

From Merck 11 Mar 2022

Targeting regulation of subcellular architecture may hold opportunities to treat metabolic diseases

Cells use their molecular architecture to regulate their metabolic functions, and repairing diseased cells' architecture to a healthier state can also repair metabolism, according to a study led by Harvard T.H. Chan School of Public Health researchers.

10 Mar 2022

Pain neuron-derived peptide protects mice from endotoxic death by enhancing brain ATP production

Sepsis is a high-mortality disease that arises when the body's immune reaction to pathogens causes multi-organ defects.

9 Mar 2022

Durable selenium nanoparticle fabrics with antiviral and antibacterial properties

Researchers graft SeNPs on polyester fabric through a flat screen-printing technique and observed their antimicrobial activity.

8 Mar 2022

Researchers take pioneering efforts to optimize the functionality of pancreatic cells produced from stem cells

Helsingin yliopisto (University of Helsinki) Insulin is a vital hormone produced by pancreatic beta cells. Type 1 diabetes is caused by the destruction of these cells, which results in patients having to replace the lost insulin with multiple daily injections.

4 Mar 2022

Gas chromatography-ion mobility spectrometry helps diagnose COVID-19 and predict disease severity

Researchers assess the ability of GC-IMS to differentiate between COVID-19 and other respiratory infections, as well as predict disease severity.

4 Mar 2022

Metabolites could be used as biomarkers for forensic diagnosis of diabetes mellitus

Determining the cause of death is one of the most crucial and challenging parts of a forensic investigation.

28 Feb 2022

New trial aims to test a non-invasive treatment for early-stage liver cancer

Researchers are set to trial a non-invasive treatment for inoperable early-stage liver cancer, thanks to an injection of over $2 million in federal government funding.

25 Feb 2022

Researchers show how the biological system can be steered with artificial organic neurons

For the first time, researchers demonstrate an artificial organic neuron, a nerve cell, that can be integrated with a living plant and an artificial organic synapse.

23 Feb 2022

Other states keep watchful eye on snags in Washington’s pioneering public-option plan

With prospects dim for the U.S. to adopt a single-payer "Medicare for All" program, health care reform advocates turned instead to an insurance plan designed by the government that could compete with private insurance plans sold on the health care exchanges.

23 Feb 2022

Ion News and Research

New insight into SARS-CoV-2 nsp14 protein opens door to new drugs

Detailed molecular map of stratum corneum can help develop new skin treatments

Irradiation of tumors with laser protons tested for the first time

Malaria drug could help treat chemotherapy-resistant head and neck cancers

Study may provide insight into the evolution of D-amino acid function in marine invertebrates

Merck and Waters to Collaborate on Extractables and Leachables Reference Library

Targeting regulation of subcellular architecture may hold opportunities to treat metabolic diseases

Pain neuron-derived peptide protects mice from endotoxic death by enhancing brain ATP production

Durable selenium nanoparticle fabrics with antiviral and antibacterial properties

Researchers take pioneering efforts to optimize the functionality of pancreatic cells produced from stem cells

Gas chromatography-ion mobility spectrometry helps diagnose COVID-19 and predict disease severity

Metabolites could be used as biomarkers for forensic diagnosis of diabetes mellitus

New trial aims to test a non-invasive treatment for early-stage liver cancer

Researchers show how the biological system can be steered with artificial organic neurons

Other states keep watchful eye on snags in Washington’s pioneering public-option plan

Exploring the potential of mosaic RBD nanoparticles to fight SARS-CoV-2

TTUHSC expert wins NIH renewal grant to continue research on neurological disorders

Novel glycation patterns help understand Omicron immune escape

Study reveals that 1PBC and niclosamide bind the same drug-binding pocket

Colchicine holds promise to reduce the risk of severe COVID-19

Enhancing confidence in chemical ionization spectrometry data eBook

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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