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Mass General Brigham launches AI company to enhance clinical trial matching

Mass General Brigham is announcing the spinout of AIwithCare, a company founded by researchers from the health system who developed an artificial intelligence (AI) screening tool that significantly outperformed manual screening for determining a patient's eligibility and enrolling them in a clinical trial.

12 Dec 2025

Mobile health intervention improves quality of life for adolescent and young adult breast cancer survivors

A mobile health (mHealth) intervention for adolescent and young adult breast cancer survivors that offered tailored support by monitoring electronic patient-reported outcomes (ePROs) significantly improved quality of life and symptoms related to vaginal and arm problems, according to results from a randomized clinical trial presented at the San Antonio Breast Cancer Symposium (SABCS), held December 9-12, 2025.

12 Dec 2025

Frequency and quantity of alcohol consumption influence cancer risk

As Americans gear up for the holiday season, new research offers a timely reminder to reflect on the long-term health effects of raising a celebratory glass – or two.

11 Dec 2025

People with epilepsy and learning disabilities face preventable early deaths

A combination of missed prevention opportunities and health inequalities can result in the early deaths of people living with epilepsy and intellectual disabilities, a study has shown.

10 Dec 2025

New AAN guideline offers treatment strategies for functional seizures

To help neurologists, mental health clinicians and other clinicians determine the best ways to help people manage functional seizures, the American Academy of Neurology has issued a new guideline, published on December 10, 2025, in Neurology, the medical journal of the American Academy of Neurology.

10 Dec 2025

Hidden infections may play a key role in driving long COVID symptoms

For millions suffering from long COVID, their persistent breathlessness, brain fog and fatigue remain a maddening mystery, but a group of leading microbiologists think they may have cracked the case.

10 Dec 2025

Family history of cardiometabolic disease linked to early heart damage in adolescents

A new study among more than 1,500 British adolescents is the first in the world to assess the association between familial cardiometabolic diseases and the offspring's risk of premature heart damage by early adulthood.

10 Dec 2025

Machine learning models can help diagnose ALS earlier from a blood sample

Using machine learning models, researchers at Michigan Medicine have identified a potential way to diagnose amyotrophic lateral sclerosis, or ALS, earlier from a blood sample, a study suggests.

10 Dec 2025

Prevention efforts for cannabis-impaired driving should also focus on older adults

With cannabis-related vehicle crashes on the rise, a new study suggests that prevention campaigns shouldn't focus just on young people.

9 Dec 2025

Research ushers in a new era of hope for patients with primary immune thrombocytopenia

More than half of patients in a Phase III clinical trial who received a limited course of the experimental monoclonal antibody ianalumab for primary immune thrombocytopenia (ITP), an autoimmune disorder that can cause life-threatening bleeding, were able to maintain safe platelet counts without serious bleeding episodes for at least one year.

9 Dec 2025

Highly sensitive CRISPR-based method designed to detect low-frequency cancer mutations

Liquid biopsy is increasingly recognized as a promising tool for cancer detection and treatment monitoring, yet its effectiveness is often limited by the extremely low levels of tumor-derived DNA circulating in the blood.

9 Dec 2025

Rural health providers could be collateral damage from $100K Trump visa fee

Bekki Holzkamm has been trying to hire a lab technician at a hospital in rural North Dakota since late summer.

9 Dec 2025

Powerful prognostic marker could enable early identification of high-risk cancer patients

Aggressive T-cell lymphoma is a rare and devastating form of blood cancer with a very low five-year survival rate.

8 Dec 2025

Serious side effects after CAR T cell therapy for multiple myeloma share a common immune root cause

Serious side effects, including neurotoxicity and intestinal inflammation, that appear weeks or months after patients receive CAR T cell therapy for multiple myeloma share a common immune root cause, are associated with high rates of death unrelated to cancer relapse-primarily infection-and may be avoidable.

8 Dec 2025

Aza-ven shows superior outcomes compared to induction chemotherapy in AML patients

In a new trial, patients newly diagnosed with acute myeloid leukemia (AML) fared significantly better with a combined regimen of azacitidine and venetoclax compared with conventional induction chemotherapy.

7 Dec 2025

Smoking fewer cigarettes does not eliminate cardiovascular disease risk

In a study funded by the National Heart, Lung, and Blood Institute, new research from Johns Hopkins Medicine adds to existing evidence that smoking fewer cigarettes does not eliminate cardiovascular disease risk, and quitting entirely is the most effective strategy for improving health.

5 Dec 2025

Medical School News and Research

Mass General Brigham launches AI company to enhance clinical trial matching

Mobile health intervention improves quality of life for adolescent and young adult breast cancer survivors

Frequency and quantity of alcohol consumption influence cancer risk

People with epilepsy and learning disabilities face preventable early deaths

New AAN guideline offers treatment strategies for functional seizures

Hidden infections may play a key role in driving long COVID symptoms

Family history of cardiometabolic disease linked to early heart damage in adolescents

Machine learning models can help diagnose ALS earlier from a blood sample

Prevention efforts for cannabis-impaired driving should also focus on older adults

Research ushers in a new era of hope for patients with primary immune thrombocytopenia

Highly sensitive CRISPR-based method designed to detect low-frequency cancer mutations

Rural health providers could be collateral damage from $100K Trump visa fee

Powerful prognostic marker could enable early identification of high-risk cancer patients

Serious side effects after CAR T cell therapy for multiple myeloma share a common immune root cause

Aza-ven shows superior outcomes compared to induction chemotherapy in AML patients

Smoking fewer cigarettes does not eliminate cardiovascular disease risk

Bacterial enzyme linked to heart complications in pneumonia

Engineered herpes virus activates potent immune responses against glioblastoma

Early pregnancy placenta models show significant effects from PFAS exposure

Rising nighttime heat is linked to shorter and more disrupted sleep

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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