Oxygen News and Research

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Breast cancer cells hijack iron-handling macrophages to promote bone metastasis and anemia

Breast cancers frequently spread to the bone, establishing tumors that are largely impervious to treatment and are associated with poor patient prognoses.

4 Sep 2025

Penn State team develops wearable sensor to track health through minimal sweat

Available on-demand, in abundance and containing multiple biomarkers, sweat is an increasingly appealing medium for monitoring health, according to researchers at Penn State.

3 Sep 2025

Novel vascularized cancer-on-a-chip model reflects the microenvironment of liver tumors

Dr. Vadim Jucaud's lab at the Terasaki Institute has developed a human vascularized liver cancer-on-a-chip model to evaluate vessel remodeling and cell death in response to embolic agents.

3 Sep 2025

Dual antiplatelet therapy after heart bypass surgery offers no added benefit over aspirin alone

Dual antiplatelet therapy after heart bypass surgery is not more effective than aspirin alone - and it increases the risk of excessive bleeding. This has now been shown in a study of 2,201 patients at 22 Nordic heart surgery units.

1 Sep 2025

Can honey protect your brain? Study reviews its potential against Alzheimer's

This review examined 27 preclinical studies on honey and Alzheimer’s disease, showing honey’s bioactive compounds counter oxidative stress, inflammation, and amyloid buildup. Despite promising lab results, no human trials exist, underscoring the need for clinical research.

1 Sep 2025

Miniature camera and AI reveal hidden dangers inside the coronary arteries

Measurements with a miniature camera inside the coronary arteries can accurately predict whether someone will suffer a recurrent heart attack.

1 Sep 2025

Aficamten outperforms beta-blockers in treating patients with obstructive hypertrophic cardiomyopathy

Aficamten treatment was associated with significant improvements in exercise capacity and symptoms compared with metoprolol in patients with symptomatic obstructive hypertrophic cardiomyopathy (HCM), according to late-breaking research presented in a Hot Line session today at ESC Congress 2025 and simultaneously published in New England Journal of Medicine.

1 Sep 2025

Ivabradine fails to prevent myocardial injury after noncardiac surgery in large clinical trial

Ivabradine did not reduce the occurrence of myocardial injury after noncardiac surgery (MINS), according to late-breaking research presented in a Hot Line session today at ESC Congress 2025.

1 Sep 2025

Trial shows no meaningful gains with mavacamten in nonobstructive hypertrophic cardiomyopathy

Mavacamten treatment at 48 weeks was not associated with significant improvements in patient-reported health status or peak oxygen consumption compared with placebo in patients with symptomatic nonobstructive hypertrophic cardiomyopathy, according to late-breaking research presented in a Hot Line session today at ESC Congress 2025 and simultaneously published in New England Journal of Medicine.

1 Sep 2025

How plant compounds could target Alzheimer’s disease from multiple angles

This review highlights how dietary polyphenols modulate Alzheimer’s disease biology through antioxidant, anti-inflammatory, and multi-target mechanisms, supported by in-silico docking analyses. Despite promise, challenges in bioavailability and brain delivery remain key hurdles to clinical translation.

31 Aug 2025

REBOOT trial finds no benefit of beta blockers after uncomplicated heart attacks

Beta blockers-drugs commonly prescribed for a range of cardiac conditions, including heart attacks-provide no clinical benefit for patients who have had an uncomplicated myocardial infarction with preserved heart function.

30 Aug 2025

New reaction approach expands possibilities for drug discovery building blocks

A new approach to an established reaction boosts the ability to synthesize vinylic ethers - key building blocks for many molecules important to human health.

28 Aug 2025

Researchers develop novel exosome-based therapeutic agent for treating traumatic CNS injuries

Traumatic injuries of the central nervous system (CNS)-such as traumatic brain injury (TBI) and traumatic spinal cord injury (SCI)-are characterized by oxidative damage and neuroinflammation.

28 Aug 2025

Omega-3 supplements lower heart rate in male athletes

Six weeks of omega-3 supplementation increases the omega-3 index and lowers heart rate in athletes, yet shows no performance advantage in endurance trials.

28 Aug 2025

Routine eye exams may help detect Alzheimer’s years before symptoms appear

Within the next few years, doctors may be able to spot signs of Alzheimer's disease and other dementias using routine eye exams well before symptoms appear, a new study suggests.

27 Aug 2025

AUF1 protein shown to suppress cellular senescence and altered metabolism

A new research paper was published in Volume 17, Issue 7 of Aging (Aging-US) on July 24, 2025, titled "RNA-binding protein AUF1 suppresses cellular senescence and glycolysis by targeting PDP2 and PGAM1 mRNAs."

27 Aug 2025

Gene editing therapy exa-cel improves quality of life in sickle cell disease and beta thalassemia

Treatment with exagamglogene autotemcel (exa-cel) led to robust and sustained improvements in quality of life for patients with severe sickle cell disease (SCD) or transfusion-dependent beta thalassemia, according to two studies published in Blood Advances.

27 Aug 2025

Oxygen News and Research

Breast cancer cells hijack iron-handling macrophages to promote bone metastasis and anemia

Penn State team develops wearable sensor to track health through minimal sweat

Novel vascularized cancer-on-a-chip model reflects the microenvironment of liver tumors

Dual antiplatelet therapy after heart bypass surgery offers no added benefit over aspirin alone

Can honey protect your brain? Study reviews its potential against Alzheimer's

Miniature camera and AI reveal hidden dangers inside the coronary arteries

Aficamten outperforms beta-blockers in treating patients with obstructive hypertrophic cardiomyopathy

Ivabradine fails to prevent myocardial injury after noncardiac surgery in large clinical trial

Trial shows no meaningful gains with mavacamten in nonobstructive hypertrophic cardiomyopathy

How plant compounds could target Alzheimer’s disease from multiple angles

REBOOT trial finds no benefit of beta blockers after uncomplicated heart attacks

New reaction approach expands possibilities for drug discovery building blocks

Researchers develop novel exosome-based therapeutic agent for treating traumatic CNS injuries

Omega-3 supplements lower heart rate in male athletes

Routine eye exams may help detect Alzheimer’s years before symptoms appear

AUF1 protein shown to suppress cellular senescence and altered metabolism

Gene editing therapy exa-cel improves quality of life in sickle cell disease and beta thalassemia

Research uncovers key role of the brain's blood flow dynamics in Alzheimer’s disease

New insights into bone remodeling process in orthodontic tooth movement under hypoxia

ATOX1 drives hepatocellular carcinoma progression through c-Myb and PI3K/AKT activation

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