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Low-intensity ultrasound emerges as key tool in regenerative medicine

Announcing a new article publication for BIO Integration journal. As a mechanical wave capable of transmitting thermal and mechanical energy, ultrasound has emerged as a pivotal tool in regenerative medicine due to its non-invasive nature.

1 Aug 2025

New radioimmunotherapy approach eliminates cancer stem cells in preclinical models of ovarian cancer

A new radioimmunotherapy approach has been shown to successfully eliminate cancer stem cells (CSCs) in preclinical models of ovarian cancer, outperforming the current gold standard.

1 Aug 2025

Researchers uncover PSAT1 gene as key to heart repair post-heart attack

Heart attacks remain a leading cause of death and disability worldwide. The permanent loss of heart muscle cells-known as cardiomyocytes-and the heart's limited regenerative capacity often led to chronic heart failure.

1 Aug 2025

Study sheds light on molecular mechanisms of brain aging

Aging and neurodegeneration are both known to disrupt the production of functional proteins in cells – a process called "proteostasis," or protein homeostasis.

31 Jul 2025

Selective impairment of translation contributes to brain aging in killifish

Aging selectively impairs the production of crucial DNA- and RNA-binding proteins, which contributes to hallmarks of aging in the brains of killifish, according to a new study.

31 Jul 2025

Infant brain activity shows faster maturation after general anesthesia

New research published today in Proceedings of the National Academy of Sciences (PNAS) finds that prolonged and/or repeated exposure to gamma-aminobutyric acid (GABA) anesthetic agents (sevoflurane, propofol) for infants in the first two months of life resulted in an accelerated maturation of brain electrical activity patterns evoked by visual stimuli when recorded at 2-5 months of age, compared to infants who did not have early general anesthesia exposure.

30 Jul 2025

Plant compounds show promise against leishmaniasis through mitochondrial targeting

Leishmaniasis, a neglected tropical disease caused by Leishmania parasites, affects millions globally. Current synthetic treatments face limitations including toxicity, cost, and resistance.

28 Jul 2025

California looked to them to close health disparities, then it backpedaled

Fortina Hernández is called "the one who knows it all." For more than two decades, the community health worker has supported hundreds of families throughout southeast Los Angeles by helping them sign up for food assistance, sharing information about affordable health coverage, and managing medications for their chronic illnesses.

28 Jul 2025

UCSF discovery points to new strategies for Alzheimer's treatment

UCSF scientists have discovered how microglia engulf and break down amyloid beta, a protein that builds up in Alzheimer's, with devastating consequences for the brain.

28 Jul 2025

New model predicts mRNA protein production, accelerating drug and vaccine discovery

A new artificial intelligence model can improve the process of drug and vaccine discovery by predicting how efficiently specific mRNA sequences will produce proteins, both generally and in various cell types. The new advance, developed through an academic-industrial partnership between The University of Texas at Austin and Sanofi, helps predict how much protein cells will produce, which can minimize the need for trial-and-error experimentation, accelerating the next generation of mRNA therapeutics.

26 Jul 2025

Review highlights the evolution of research related to implantable brain-computer interfaces

A review published in Advanced Science highlights the evolution of research related to implantable brain-computer interfaces (iBCIs), which decode brain signals that are then translated into commands for external devices to potentially benefit individuals with impairments such as loss of limb function or speech.

23 Jul 2025

Toti-N-Seq breakthrough enables universal and scalable single-cell profiling

The rapid advancement of single-cell and single-nucleus RNA sequencing (sc/snRNA-seq) has opened unprecedented windows into cellular diversity, yet existing methods for multiplexing samples struggle with scalability and accuracy.

22 Jul 2025

Australian study uncovers first potential prophylactic treatment against HTLV-1

Around 10 million people globally live with the life-threatening virus HTLV-1. Yet it remains a poorly understood disease that currently has no preventative treatments and no cure.

21 Jul 2025

Liver identified as key driver of cancer cachexia

Many people with cancer experience dramatic loss of muscle and fat tissue. In many cases, even the heart muscle is affected, which further weakens the body.

21 Jul 2025

Muscle-derived vesicles heal damaged cells and reverse disease in new study

Researchers discovered that mitochondria-rich extracellular vesicles (Ti-mitoEVs) from skeletal muscle can deliver healthy mitochondria to damaged cells, restoring energy and promoting tissue repair in mice. The approach reversed acute muscle injury and chronic kidney disease, offering a promising new regenerative therapy.

21 Jul 2025

MicroRNAs emerge as key players in soft tissue sarcoma

A new editorial was published in Volume 16 of Oncotarget on July 16, 2025, titled "microRNAs in soft tissue sarcoma: State of the art and barriers to translation."

18 Jul 2025

Cuproptosis offers new hope for treating inflammatory bowel disease and colorectal cancer

Cuproptosis represents a novel mechanism of cell death characterized by intracellular copper ion accumulation.

18 Jul 2025

Study identifies SDR42E1's role in vitamin D pathway

Vitamin D is not only an essential nutrient, but also the precursor of the hormone calcitriol, indispensable for health: it regulates the uptake of phosphate and calcium necessary for bones by the intestines, as well as cell growth and the proper function of muscles, nerve cells, and the immune system.

18 Jul 2025

Prestigious Stephenson Scholar Grants support cutting-edge pancreatic cancer studies

The Stephenson Global Pancreatic Cancer Research Institute and its partner City of Hope, one of the country's largest and most advanced cancer research and treatment organizations, today announced the six inaugural recipients of the prestigious Stephenson Scholar Grants, awarding $5.25 million to support high-impact research aimed at transforming the understanding, early detection and treatment of pancreatic cancer.

16 Jul 2025

UNM researchers get $1 million grant to launch early clinical trial for Alzheimer’s vaccine

University of New Mexico researchers have received funding to launch an early-stage clinical trial of a vaccine engineered to clear pathological tau protein from the brains of patients suffering from Alzheimer's dementia.

15 Jul 2025