Antigen News and Research

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Reprogrammed endothelial cells for treatment of vascular disorders

A research team at Weill Cornell Medical College has discovered a way to utilize diagnostic prenatal amniocentesis cells, reprogramming them into abundant and stable endothelial cells capable of regenerating damaged blood vessels and repairing injured organs.

19 Oct 2012

Long-term multivitamin use associated with prevention of cancer in middle-aged and older men

In a randomized trial that included nearly 15,000 male physicians, long-term daily multivitamin use resulted in a modest but statistically significant reduction in cancer after more than a decade of treatment and follow-up, according to a study appearing in JAMA.

19 Oct 2012

Therapeutic HPV16 and HPV18 vaccine ‘may eliminate infection’

A candidate vaccine against human papillomavirus serotypes 16 and 18 appears to induce robust immune responses to antigens, potentially leading to the elimination of virus-infected cells and regression of dysplasia, say US investigators.

15 Oct 2012

Regulatory B cells may provide effective treatment for severe autoimmune diseases

Reproducing a rare type of B cell in the laboratory and infusing it back into the body may provide an effective treatment for severe autoimmune diseases such as multiple sclerosis or rheumatoid arthritis, according to researchers at Duke University Medical Center.

15 Oct 2012

UCI neuro-oncologist to lead DCVax Phase II trial in glioblastoma multiforme

UC Irvine doctors are enrolling patients with the deadly brain tumor glioblastoma multiforme in a clinical trial of a vaccine that may prevent the cancer's return or spread after surgery.

11 Oct 2012

Feline leukemia virus becoming uncommon with lymphoma

Rates of feline leukemia virus in domestic cats with lymphoma have decreased in recent years, suggesting alternative etiologies for this cancer subtype, show German study results.

10 Oct 2012

Genocea raises $30M in Series C financing round

Genocea Biosciences, Inc., a clinical-stage company advancing innovative T cell vaccines for infectious diseases, has raised $30 million in a Series C financing round.

10 Oct 2012

GSK, Aeras to advance clinical development of TB vaccine

Aeras announces that it has signed an agreement with GlaxoSmithKline Vaccines, S.A. (GSK) to jointly advance the clinical development of an investigational tuberculosis (TB) vaccine containing GSK's proprietary M72 antigen and AS01E adjuvant.

10 Oct 2012

Researchers discover 8 new loci associated with susceptibility to atopic dermatitis

Researchers at the RIKEN Center for Genomic Medicine (CGM) and their colleagues have identified 8 new loci associated with susceptibility to atopic dermatitis in the Japanese population.

8 Oct 2012

CytoDyn announces update on feline immunodeficiency virus therapeutic antibody program

CytoDyn Inc., a biotechnology company focused on the development of new therapies for combating infection with immune deficiency viruses, announced today that it is presenting an update on its Feline Immunodeficiency Virus (FIV) therapeutic antibody program at the 19th West Coast Retrovirus meeting in Palm Springs, California.

8 Oct 2012

NIH awards $2.1M grant to study possible ways to fight cancer

A professor with the University of Houston Cullen College of Engineering has won a $2.1 million grant to study the best ways to modify human immune cells to fight against cancer.

6 Oct 2012

Emergent receives BARDA contract to advance development of novel rPA anthrax vaccine

Emergent BioSolutions announced today that, after completion of an inter-agency In Process Review, the Biomedical Advanced Research Development Authority (BARDA) of the U.S. Department of Health and Human Services (HHS) has exercised a contract option to further advance the development of PreviThrax (Recombinant Protective Antigen Anthrax Vaccine, Purified), the company's novel rPA anthrax vaccine candidate.

5 Oct 2012

FDA licenses Quotient’s ALBAsera products

Quotient Biodiagnostics, Inc., a supplier of innovative and high-quality transfusion diagnostic products to hospitals, blood banks and other healthcare institutions, is pleased to announce that its range of ALBAsera Rare Antisera products have been licensed for sale by the U.S. Food and Drug Administration (FDA).

5 Oct 2012

Sublingual immunotherapy highly effective for chronic allergy and asthma sufferers

Could it be that those with allergic rhinitis (hay fever) and childhood nasal allergies can finally get a break from their allergies and their allergy shots? Chicago's leading allergy, asthma, and immunology expert, Dr. Brian Rotskoff, who treats a large number of Chicago pediatric allergy patients, is happy to say, "Yes!"

5 Oct 2012

Circassia commences ToleroMune phase 3 trial in cat allergen-induced rhinoconjunctivitis

Circassia Ltd, a specialty biopharmaceutical company focused on allergy, today announced the start of a pivotal phase 3 trial of its investigational ToleroMune cat allergy treatment for cat allergen-induced rhinoconjunctivitis.

4 Oct 2012

Routine screening influences outcomes in prostate cancer after surgery

Men who undergo radical prostatectomy for a tumor that was detected by screening show better long-term outcomes than their peers who undergo the surgery after opportunistic diagnosis, study results show.

3 Oct 2012

Haploidentical bone marrow transplants for sickle cell disease: an interview with Dr. Javier Bolaños Meade

Bone marrow transplant (also called stem cell transplant) is a medical intervention that allows a physician to deliver very high doses of chemotherapy (if needed) but more importantly, deliver a new immune system to the patient to fight a disease (such as cancer).

3 Oct 2012

Mothers’ CD4 cells ‘remember’ their babies

A breakthrough in understanding a mother’s immune response during pregnancy suggests a new direction for treating autoimmune diseases.

2 Oct 2012

Novel therapy shows promise in treating multiple myeloma following stem cell transplants

A novel therapy in the early stages of development at Virginia Commonwealth University Massey Cancer Center shows promise in providing lasting protection against the progression of multiple myeloma following a stem cell transplant by making the cancer cells easier targets for the immune system.

2 Oct 2012

Autoimmune disease myasthenia gravis halted in mice

Working with mice, Johns Hopkins researchers say they have developed a gene-based therapy to stop the rodent equivalent of the autoimmune disease myasthenia gravis by specifically targeting the destructive immune response the disorder triggers in the body.

1 Oct 2012

Antigen News and Research

Reprogrammed endothelial cells for treatment of vascular disorders

Long-term multivitamin use associated with prevention of cancer in middle-aged and older men

Therapeutic HPV16 and HPV18 vaccine ‘may eliminate infection’

Regulatory B cells may provide effective treatment for severe autoimmune diseases

UCI neuro-oncologist to lead DCVax Phase II trial in glioblastoma multiforme

Feline leukemia virus becoming uncommon with lymphoma

Genocea raises $30M in Series C financing round

GSK, Aeras to advance clinical development of TB vaccine

Researchers discover 8 new loci associated with susceptibility to atopic dermatitis

CytoDyn announces update on feline immunodeficiency virus therapeutic antibody program

NIH awards $2.1M grant to study possible ways to fight cancer

Emergent receives BARDA contract to advance development of novel rPA anthrax vaccine

FDA licenses Quotient’s ALBAsera products

Sublingual immunotherapy highly effective for chronic allergy and asthma sufferers

Circassia commences ToleroMune phase 3 trial in cat allergen-induced rhinoconjunctivitis

Routine screening influences outcomes in prostate cancer after surgery

Haploidentical bone marrow transplants for sickle cell disease: an interview with Dr. Javier Bolaños Meade

Mothers’ CD4 cells ‘remember’ their babies

Novel therapy shows promise in treating multiple myeloma following stem cell transplants

Autoimmune disease myasthenia gravis halted in mice

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