Clinical Trial News and Research

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Researchers use genetics to identify potential drugs for early management of COVID-19

A new study using human genetics suggests researchers should prioritize clinical trials of drugs that target two proteins to manage COVID-19 in its early stages.

9 Apr 2021

Toward a transformative therapy for sickle cell patients

For the millions of people worldwide who have sickle cell disease, there are only a few treatment options, which include risky bone marrow transplants, gene therapy or other treatments that address a subset of symptoms.

9 Apr 2021

Researchers reveal blood clot risk and anticoagulation benefits in discharged COVID-19 patients

In the largest study of its kind, Feinstein Institutes for Medical Research and Northwell COVID-19 Research Consortium researchers reveal blood clot risk and anticoagulation benefits in hospitalized coronavirus disease 2019 (COVID-19) patients who have been recently discharged from the hospital.

9 Apr 2021

Phase 2 clinical trial launched in Thailand to evaluate IL-15 agonist as therapy to reduce HIV reservoir

The U.S. Military HIV Research Program (MHRP) at the Walter Reed Army Institute of Research last week launched a Phase 2 clinical trial in Thailand to evaluate an interleukin-15 (IL-15) superagonist, ImmunityBio's Anktiva (also called N-803), administered during acute HIV infection as an experimental therapy to target establishment of the HIV reservoir at a very early stage.

8 Apr 2021

Phase 3 clinical trial tests new treatment for brain metastases from small-cell lung cancer

A new phase 3 randomized clinical trial overseen by CU Cancer Center member Chad Rusthoven, MD, and Vinai Gondi, MD, from Northwestern University, is testing whether a new treatment approach could result in improved outcomes for patients with small cell lung cancer (SCLC) that has spread to the brain.

8 Apr 2021

Moderna COVID-19 vaccine ensures long-term protection against SARS-CoV-2 infection, suggests study

A recent report published in the New England Journal of Medicine has revealed that the COVID-19 vaccine developed by Moderna, Inc, USA, is capable of inducing robust and durable antibody responses for at least six months post-vaccination.

8 Apr 2021

Targeted therapy achieves excellent outcomes, reduces side effects in high-risk Hodgkin lymphoma

Scientists are reporting results of the first frontline clinical trial to use targeted therapy to treat high-risk pediatric Hodgkin lymphoma.

8 Apr 2021

Compassion training can improve the well-being of relatives of people with mental illness

If relatives of people with mental illness become better at accepting the difficult emotions and life events they experience - which is what training in compassion is about - their anxiety, depression and stress is reduced.

8 Apr 2021

Michigan Medicine to kick off first national study on allergic reactions to COVID-19 vaccines

In a carefully controlled study, Michigan Medicine researchers will kick off the first national trial to study allergic reactions to the COVID-19 mRNA vaccines.

7 Apr 2021

NIH-funded clinical trial begins study of systemic allergic reactions to COVID-19 vaccines

A clinical trial is underway to determine whether people who are highly allergic or have a mast cell disorder are at increased risk for an immediate, systemic allergic reaction to the Moderna or Pfizer-BioNTech COVID-19 vaccines.

7 Apr 2021

Pandemic's mitigation efforts may have contributed to drop in clinical trial completion rates

Social distancing and lockdowns may have reduced the spread of COVID-19, but researchers from Penn State College of Medicine also report those actions may have affected clinical researchers' ability to finish trials.

7 Apr 2021

A proprioceptive control strategy for management of low back pain

Low back pain in the elderly is the result of poor “proprioception,” or the body’s ability to perceive its own position in space, caused by a deterioration of sensory receptors in their muscles called proprioceptors.

7 Apr 2021

SlowMo therapy helps treat paranoid thoughts in people experiencing psychosis

A new clinical trial from King's College London's Institute of Psychiatry, Psychology, & Neuroscience, in collaboration with Oxford University, Oxford Health NHS Foundation Trust, Sussex University, and Sussex Partnership NHS Foundation Trust has established an innovative therapy as an effective means of treating paranoid thoughts in people experiencing psychosis.

7 Apr 2021

New stem cell therapy shows promise to prevent diabetes-related amputations

According to the results of a phase 1 clinical trial just published in STEM CELLS Translational Medicine, a new stem cell therapy shows promise of making diabetes-related amputations a thing of the past.

7 Apr 2021

New test for Lyme disease can reliably distinguish between early- and late-stage patients

For those who live in an area blighted by ticks, the threat of Lyme disease can cast a shadow over the joy of spring and summer.

7 Apr 2021

Advancing the Diagnosis and Treatment of Ovarian Cancer

In this interview, News-Medical talks to Dr. Marcos Quintela Vasquez about the work he is conducting regarding the diagnosis and treatment of ovarian cancer in partnership with Porvair Sciences.

From Porvair Sciences Limited 7 Apr 2021

CoVIg-19 Plasma Alliance announces outcomes of NIH-funded Phase 3 ITAC clinical trial

The CoVIg-19 Plasma Alliance today announced that the Phase 3 Inpatient Treatment with Anti-Coronavirus Immunoglobulin (ITAC) clinical trial sponsored and funded by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), did not meet its endpoints. No serious safety signals were raised in the trial.

7 Apr 2021

Study reveals new mutations that make cancer resistant to KRAS-targeted therapies

A gene called KRAS is one of the most commonly mutated genes in all human cancers, and targeted drugs that inhibit the protein expressed by mutated KRAS have shown promising results in clinical trials, with potential approvals by the U.S. Food and Drug Administration anticipated later this year.

7 Apr 2021

Expert calls for swift action to avoid chronic health conditions caused by COVID-19

A tsunami of chronic health conditions as a result of the SARS-CoV-2 pandemic, especially cardiometabolic disease, may produce an enormous wave of death and disability that demands immediate, comprehensive strategies.

7 Apr 2021

Phase 1 clinical trial to test a new, potential method against cancer

A potential new weapon against cancer is entering the first phase of clinical trials thanks to a collaboration between Spectrum Health, the Lansing-based company Niowave and Michigan State University.

7 Apr 2021

Clinical Trial News and Research

Researchers use genetics to identify potential drugs for early management of COVID-19

Toward a transformative therapy for sickle cell patients

Researchers reveal blood clot risk and anticoagulation benefits in discharged COVID-19 patients

Phase 2 clinical trial launched in Thailand to evaluate IL-15 agonist as therapy to reduce HIV reservoir

Phase 3 clinical trial tests new treatment for brain metastases from small-cell lung cancer

Moderna COVID-19 vaccine ensures long-term protection against SARS-CoV-2 infection, suggests study

Targeted therapy achieves excellent outcomes, reduces side effects in high-risk Hodgkin lymphoma

Compassion training can improve the well-being of relatives of people with mental illness

Michigan Medicine to kick off first national study on allergic reactions to COVID-19 vaccines

NIH-funded clinical trial begins study of systemic allergic reactions to COVID-19 vaccines

Pandemic's mitigation efforts may have contributed to drop in clinical trial completion rates

A proprioceptive control strategy for management of low back pain

SlowMo therapy helps treat paranoid thoughts in people experiencing psychosis

New stem cell therapy shows promise to prevent diabetes-related amputations

New test for Lyme disease can reliably distinguish between early- and late-stage patients

Advancing the Diagnosis and Treatment of Ovarian Cancer

CoVIg-19 Plasma Alliance announces outcomes of NIH-funded Phase 3 ITAC clinical trial

Study reveals new mutations that make cancer resistant to KRAS-targeted therapies

Expert calls for swift action to avoid chronic health conditions caused by COVID-19

Phase 1 clinical trial to test a new, potential method against cancer

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